(Q55228036)

English

Estrogen receptor modulators genistein, daidzein and ERB-041 inhibit cell migration, invasion, proliferation and sphere formation via modulation of FAK and PI3K/AKT signaling in ovarian cancer.

scientific article published in May 2018

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

27 June 2018

http://europepmc.org/abstract/PMC/5930957

Estrogen receptor modulators genistein, daidzein and ERB-041 inhibit cell migration, invasion, proliferation and sphere formation via modulation of FAK and PI3K/AKT signaling in ovarian cancer. (English)

1 reference

Europe PubMed Central

PMC publication ID

27 June 2018

http://europepmc.org/abstract/PMC/5930957

1 reference

based on heuristic

inferred from title

Hextan Y S Ngan

object named as

Hextan Y S Ngan

6

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author name string

Karen K L Chan

1

1 reference

Europe PubMed Central

PMC publication ID

27 June 2018

http://europepmc.org/abstract/PMC/5930957

Michelle K Y Siu

2

1 reference

Europe PubMed Central

PMC publication ID

27 June 2018

http://europepmc.org/abstract/PMC/5930957

Yu-Xin Jiang

3

1 reference

Europe PubMed Central

PMC publication ID

27 June 2018

http://europepmc.org/abstract/PMC/5930957

Jing-Jing Wang

4

1 reference

Europe PubMed Central

PMC publication ID

27 June 2018

http://europepmc.org/abstract/PMC/5930957

Thomas H Y Leung

5

1 reference

Europe PubMed Central

PMC publication ID

27 June 2018

http://europepmc.org/abstract/PMC/5930957

publication date

1 May 2018

1 reference

Europe PubMed Central

PMC publication ID

27 June 2018

http://europepmc.org/abstract/PMC/5930957

Cancer Cell International

1 reference

Europe PubMed Central

PMC publication ID

27 June 2018

http://europepmc.org/abstract/PMC/5930957

18

1 reference

Europe PubMed Central

PMC publication ID

27 June 2018

http://europepmc.org/abstract/PMC/5930957

65

1 reference

Europe PubMed Central

PMC publication ID

27 June 2018

http://europepmc.org/abstract/PMC/5930957

copyright license

Creative Commons Attribution 4.0 International

1 May 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

https://scigraph.springernature.com/pub.10.1186/s12935-018-0559-2

0 references

Effect of estrogen receptor β agonists on proliferation and gene expression of ovarian cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

Agonists and knockdown of estrogen receptor β differentially affect invasion of triple-negative breast cancer cells in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

Metformin induces degradation of cyclin D1 via AMPK/GSK3β axis in ovarian cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

Understanding genistein in cancer: The "good" and the "bad" effects: A review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

An updated review of dietary isoflavones: Nutrition, processing, bioavailability and impacts on human health

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

Genistein suppressed epithelial-mesenchymal transition and migration efficacies of BG-1 ovarian cancer cells activated by estrogenic chemicals via estrogen receptor pathway and downregulation of TGF-β signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

Genistein and cancer: current status, challenges, and future directions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

PI3K/Akt/mTOR signaling pathway in cancer stem cells: from basic research to clinical application

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

Diosgenin induces G2/M cell cycle arrest and apoptosis in human hepatocellular carcinoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

FAK in cancer: mechanistic findings and clinical applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

PI3K/AKT/mTOR signaling pathway as a therapeutic target for ovarian cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

7-difluoromethoxyl-5,4'-di-n-octyl genistein inhibits ovarian cancer stem cell characteristics through the downregulation of FOXM1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

Targeting estrogen receptor subtypes (ERα and ERβ) with selective ER modulators in ovarian cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

Genistein as a Potential Anticancer Agent against Ovarian Cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

Genistein-inhibited cancer stem cell-like properties and reduced chemoresistance of gastric cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

Targeting estrogen receptor-β for the prevention of nonmelanoma skin cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

Genistein decreases the breast cancer stem-like cell population through Hedgehog pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

Erb-041, an estrogen receptor-β agonist, inhibits skin photocarcinogenesis in SKH-1 hairless mice by downregulating the WNT signaling pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

Daidzein causes cytochrome c-mediated apoptosis via the Bcl-2 family in human hepatic cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

Genistein and daidzein: different molecular effects on prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

Isoflavones: estrogenic activity, biological effect and bioavailability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

Hormone response in ovarian cancer: time to reconsider as a clinical target?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

Potential role of estrogen receptor beta as a tumor suppressor of epithelial ovarian cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

Cancer statistics, 2012

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

Development of subtype-selective oestrogen receptor-based therapeutics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

Focal adhesion kinase and its signaling pathways in cell migration and angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

p21-activated kinase 4 regulates ovarian cancer cell proliferation, migration, and invasion and contributes to poor prognosis in patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

Daidzein induces MCF-7 breast cancer cell apoptosis via the mitochondrial pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

Inhibitory effects of genistein on metastasis of human hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

Genistein induces G2/M cell cycle arrest and apoptosis of human ovarian cancer cells via activation of DNA damage checkpoint pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

MEK4 function, genistein treatment, and invasion of human prostate cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

Estrogen Receptors alpha and beta as determinants of gene expression: influence of ligand, dose, and chromatin binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

Estrogen receptor {beta}1 exerts antitumoral effects on SK-OV-3 ovarian cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

Estrogen receptor (ER)-beta isoforms: a key to understanding ER-beta signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

Design and synthesis of aryl diphenolic azoles as potent and selective estrogen receptor-beta ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

Genistein-induced cell cycle arrest and apoptosis in a head and neck squamous cell carcinoma cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 June 2018

A Selective Estrogen Receptor Beta Agonist for the Treatment of Hot Flushes: Phase 2 Clinical Trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

13 August 2018

Stem cell transcription factor NANOG controls cell migration and invasion via dysregulation of E-cadherin and FoxJ1 and contributes to adverse clinical outcome in ovarian cancers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

13 August 2018

Targeting the AKT/GSK3β/cyclin D1/Cdk4 survival signaling pathway for eradication of tumor radioresistance acquired by fractionated radiotherapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

13 August 2018

Genistein-induced neuronal apoptosis and G2/M cell cycle arrest is associated with MDC1 up-regulation and PLK1 down-regulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

13 August 2018

Soy isoflavones suppress invasiveness of breast cancer cells by the inhibition of NF-kappaB/AP-1-dependent and -independent pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

13 August 2018

Soy and isoflavone intake are associated with reduced risk of ovarian cancer in southeast china

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

13 August 2018

Isoflavones inhibit proliferation of ovarian cancer cells in vitro via an estrogen receptor-dependent pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

13 August 2018

Effects of structurally related flavonoids on cell cycle progression of human melanoma cells: regulation of cyclin-dependent kinases CDK2 and CDK1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

13 August 2018

Estrogen Receptor Subtypes in Ovarian Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5930957

30 November 2018

Correlation between Steroid Hormone Receptors, Histological and Clinical Parameters in Ovarian Carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/29743815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genistein arrests cell cycle progression at G2-M

1 reference

https://pubmed.ncbi.nlm.nih.gov/29743815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preclinical characterization of selective estrogen receptor beta agonists: new insights into their therapeutic potential

1 reference

https://pubmed.ncbi.nlm.nih.gov/29743815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer stem cells: an evolving concept

1 reference

https://pubmed.ncbi.nlm.nih.gov/29743815

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/S12935-018-0559-2

1 reference

Europe PubMed Central

PMC publication ID

27 June 2018

http://europepmc.org/abstract/PMC/5930957

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

27 June 2018

http://europepmc.org/abstract/PMC/5930957

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

27 June 2018

http://europepmc.org/abstract/PMC/5930957

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