(Q55436455)

9 July 2018

title

Environmental change exposes beneficial epistatic interactions in a catalytic RNA. (English)

1 reference

9 July 2018

1 reference

Eric J Hayden

1

1 reference

9 July 2018

Andreas Wagner

series ordinal

2

1 reference

9 July 2018

publication date

20 June 2012

1 reference

9 July 2018

Proceedings of the Royal Society B

number of pages

8

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

9 July 2018

volume

279

1 reference

9 July 2018

page(s)

3418-3425

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9 July 2018

issue

1742

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9 July 2018

Cryptic genetic variation promotes rapid evolutionary adaptation in an RNA enzyme

cites work

1 reference

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Diminishing returns epistasis among beneficial mutations decelerates adaptation

9 July 2018

1 reference

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Second-order selection for evolvability in a large Escherichia coli population

9 July 2018

1 reference

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Gene-environment interactions in human disease: nuisance or opportunity?

9 July 2018

1 reference

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Artificial gene amplification reveals an abundance of promiscuous resistance determinants in Escherichia coli

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

The rate of fitness-valley crossing in sexual populations.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

Mutational effects and the evolution of new protein functions.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

Gene--environment-wide association studies: emerging approaches

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

Finding the missing heritability of complex diseases

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

In the light of directed evolution: pathways of adaptive protein evolution

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

The rate at which asexual populations cross fitness valleys

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

Epistasis--the essential role of gene interactions in the structure and evolution of genetic systems

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

Constructing and analyzing the fitness landscape of an experimental evolutionary process

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

Genome-wide association studies for complex traits: consensus, uncertainty and challenges

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

Beneficial mutation selection balance and the effect of linkage on positive selection

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

The speed of evolution and maintenance of variation in asexual populations

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

Empirical fitness landscapes reveal accessible evolutionary paths

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

Darwinian evolution can follow only very few mutational paths to fitter proteins

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

The biochemical architecture of an ancient adaptive landscape

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

Perspective: Sign epistasis and genetic constraint on evolutionary trajectories

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

Assembly PCR oligo maker: a tool for designing oligodeoxynucleotides for constructing long DNA molecules for RNA production.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

The 'evolvability' of promiscuous protein functions

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

Stability and the evolvability of function in a model protein

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

Stochastic tunnels in evolutionary dynamics

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

The non-Watson-Crick base pairs and their associated isostericity matrices

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

The rate of compensatory evolution

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

Activity and thermostability of the small self-splicing group I intron in the pre-tRNA(lle) of the purple bacterium Azoarcus

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

Thermodynamic effects of formamide on DNA stability

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

Natural Selection and the Concept of a Protein Space

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

The intervening sequence RNA of Tetrahymena is an enzyme

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

Towards a general theory of adaptive walks on rugged landscapes.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

Negative epistasis between beneficial mutations in an evolving bacterial population

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

Compensatory evolution in mitochondrial tRNAs navigates valleys of low fitness

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

Sizing up human height variation.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

Thermodynamic characterization of single mismatches found in naturally occurring RNA.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

Rapid evolutionary escape by large populations from local fitness peaks is likely in nature.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

Equally parsimonious pathways through an RNA sequence space are not equally likely.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3396916

Molecular Evolution Over the Mutational Landscape

12 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1098%2FRSPB.2012.0956

A systems analysis of mutational effects in HIV-1 protease and reverse transcriptase

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1098%2FRSPB.2012.0956

Impact of epistasis and pleiotropy on evolutionary adaptation

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22719036

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1098/RSPB.2012.0956

1 reference

9 July 2018

release_v5v7n5qo4jd5djh2mq2zplg53i

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/v5v7n5qo4jd5djh2mq2zplg53i

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMCID

3396916

1 reference

9 July 2018

PubMed ID

22719036

1 reference

9 July 2018