(Q55527156)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29988039%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

title

Glutathione depletion induces ferroptosis, autophagy, and premature cell senescence in retinal pigment epithelial cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29988039%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

1 reference

1 reference

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29988039%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

Yizhi Liu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29988039%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

author name string

Yun Sun

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29988039%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

Yingfeng Zheng

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29988039%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

Chunxiao Wang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29988039%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

publication date

9 July 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29988039%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

published in

Cell Death and Disease

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29988039%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29988039%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29988039%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

page(s)

753

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29988039%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

5 April 2020

copyright license

start time

1 July 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6037763/fullTextXML

inferred from PubMed Central ID database lookup

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Oxidative stress-induced premature senescence dysregulates VEGF and CFH expression in retinal pigment epithelial cells: Implications for Age-related Macular Degeneration.

15 July 2018

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15 July 2018

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Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

15 July 2018

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Synchronized renal tubular cell death involves ferroptosis.

15 July 2018

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15 July 2018

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15 July 2018

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15 July 2018

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15 July 2018

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15 July 2018

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Stimulation of GSH synthesis to prevent oxidative stress-induced apoptosis by hydroxytyrosol in human retinal pigment epithelial cells: activation of Nrf2 and JNK-p62/SQSTM1 pathways

15 July 2018

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15 July 2018

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15 July 2018

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15 July 2018

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15 July 2018

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PI3K/Akt and mTOR/p70S6K pathways mediate neuroprotectin D1-induced retinal pigment epithelial cell survival during oxidative stress-induced apoptosis

15 July 2018

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15 July 2018

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15 July 2018

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Protective effect of clusterin from oxidative stress-induced apoptosis in human retinal pigment epithelial cells

15 July 2018

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15 July 2018

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Prematurely senescent ARPE-19 cells display features of age-related macular degeneration

15 July 2018

1 reference

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15 July 2018

1 reference

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Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4

15 July 2018

1 reference

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Activation of mitogen-activated protein kinases is essential for hydrogen peroxide -induced apoptosis in retinal pigment epithelial cells

15 July 2018

1 reference

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Different death stimuli evoke apoptosis via multiple pathways in retinal pigment epithelial cells

15 July 2018

1 reference

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15 July 2018

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Pigment epithelium-derived factor inhibits oxidative stress-induced cell death by activation of extracellular signal-regulated kinases in cultured retinal pigment epithelial cells

15 July 2018

1 reference

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Lipids and lipid peroxidation products in the pathogenesis of age-related macular degeneration

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037763

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15 July 2018

1 reference

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Oxidative stress-induced mitochondrial DNA damage in human retinal pigment epithelial cells: a possible mechanism for RPE aging and age-related macular degeneration

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037763

Increased oxidant-induced apoptosis in cultured nondividing human retinal pigment epithelial cells

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037763

Plasma malondialdehyde and nitric oxide levels in age related macular degeneration

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037763

Structure, function, and regulation of human cystine/glutamate transporter in retinal pigment epithelial cells

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037763

Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037763

The role of oxidative stress in the pathogenesis of age-related macular degeneration.

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037763

Glutathione, oxidative stress and neurodegeneration

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037763

Oxidative damage and protection of the RPE.

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037763

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

15 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037763

Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037763

How do we fit ferroptosis in the family of regulated cell death?

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037763

Autophagy impairment with lysosomal and mitochondrial dysfunction is an important characteristic of oxidative stress-induced senescence

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037763

xCT deficiency induces autophagy via endoplasmic reticulum stress activated p38-mitogen-activated protein kinase and mTOR in sut melanocytes.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037763

Dehydroepiandrosterone prevents linoleic acid-induced endothelial cell senescence by increasing autophagy.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037763

Glutathione Depletion Induces Spermatogonial Cell Autophagy

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037763

Apoptosis and autophagy have opposite roles on imatinib-induced K562 leukemia cell senescence.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037763

Autophagy mediates the process of cellular senescence characterizing bile duct damages in primary biliary cirrhosis

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037763

Subtoxic oxidative stress induces senescence in retinal pigment epithelial cells via TGF-beta release

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037763

Oxidation as a post-translational modification that regulates autophagy.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037763

Oxidant-mediated Akt activation in human RPE cells.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037763

Hepatocyte growth factor protects RPE cells from apoptosis induced by glutathione depletion

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037763

Cysteine starvation activates the redox-dependent mitochondrial permeability transition in retinal pigment epithelial cells

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037763

Lipid diffusion in sperm plasma membranes exposed to peroxidative injury from oxygen free radicals

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037763

Association of increased autophagic inclusions labeled for beta-galactosidase with fibroblastic aging

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037763

Hydrogen peroxide-induced cell death in a human retinal pigment epithelial cell line, ARPE-19.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037763

Prevention of oxidant-induced cell death by lysosomotropic iron chelators

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037763

Prevention of glutathione depletion-induced apoptosis in cultured human RPE cells by flupirtine.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037763

Bcl-2 overexpression increases survival in human retinal pigment epithelial cells exposed to H(2)O(2).

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037763

Protection of retinal pigment epithelium from oxidative injury by glutathione and precursors.

12 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6037763

A specific, sensitive, and rapid method for the determination of glutathione and its application in ocular tissues

12 August 2018

1 reference

https://api.crossref.org/works/10.1038%2FS41419-018-0794-4

7 January 2021

Subcellular compartmentation of glutathione and glutathione precursors. A high resolution immunogold analysis of the outer retina of guinea pig

1 reference

https://api.crossref.org/works/10.1038%2FS41419-018-0794-4

7 January 2021

Antioxidant enzymes in the aging human retinal pigment epithelium

1 reference

https://api.crossref.org/works/10.1038%2FS41419-018-0794-4

7 January 2021

Autophagy may precede cellular senescence of bile ductular cells in ductular reaction in primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1038%2FS41419-018-0794-4

7 January 2021

Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method

1 reference

https://api.crossref.org/works/10.1038%2FS41419-018-0794-4

7 January 2021

Metallothionein shows an age-related decrease in human macular retinal pigment epithelium

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29988039

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/S41419-018-0794-4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29988039%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29988039%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

1 reference