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Mechanisms of ferroptosis

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31 March 2020

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8 February 2021

Mechanisms of ferroptosis (English)

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31 March 2020

2 references

3 April 2019

8 February 2021

glutathione peroxidase

1 reference

28 September 2019

plasma membrane

1 reference

12 October 2019

reactive oxygen species

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4 November 2019

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20 November 2019

1 reference

1 reference

based on heuristic

inferred from title

2

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31 March 2020

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Jennifer Yinuo Cao

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1 June 2016

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8 February 2021

Cellular and Molecular Life Sciences

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3 April 2019

28 September 2019

12 October 2019

4 November 2019

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2195-2209

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11-12

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6 references

Europe PubMed Central

3 April 2019

Europe PubMed Central

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Europe PubMed Central

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Selective inhibition of hypoxia-inducible factor (HIF) prolyl-hydroxylase 1 mediates neuroprotection against normoxic oxidative death via HIF- and CREB-independent pathways

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Cloning and expression of a plasma membrane cystine/glutamate exchange transporter composed of two distinct proteins

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Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death

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HSPB1 as a novel regulator of ferroptotic cancer cell death

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Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

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Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine)

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12-Lipoxygenase plays a key role in cell death caused by glutathione depletion and arachidonic acid in rat oligodendrocytes

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The 5-Lipoxygenase Inhibitor Zileuton Confers Neuroprotection against Glutamate Oxidative Damage by Inhibiting Ferroptosis

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28 September 2017

Loss of cysteinyl-tRNA synthetase (CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation

1 reference

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28 September 2017

Glutaminolysis and Transferrin Regulate Ferroptosis

1 reference

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28 September 2017

Ferroptosis is Involved in Acetaminophen Induced Cell Death

1 reference

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28 September 2017

T cell lipid peroxidation induces ferroptosis and prevents immunity to infection.

1 reference

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28 September 2017

Ferroptosis as a p53-mediated activity during tumour suppression

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xCT, not just an amino-acid transporter: a multi-functional regulator of microbial infection and associated diseases

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Measuring glutathione redox potential of HIV-1-infected macrophages

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28 September 2017

Synchronized renal tubular cell death involves ferroptosis.

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28 September 2017

Sorafenib induces ferroptosis in human cancer cell lines originating from different solid tumors.

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Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms.

1 reference

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28 September 2017

Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis

1 reference

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28 September 2017

Unravelling mechanisms of p53-mediated tumour suppression

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28 September 2017

Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models

1 reference

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28 September 2017

Regulation of ferroptotic cancer cell death by GPX4

1 reference

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28 September 2017

The role of iron and reactive oxygen species in cell death

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Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia

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Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses

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Iron-dependent cell death of hepatocellular carcinoma cells exposed to sorafenib

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The plasma membrane channel ORAI1 mediates detrimental calcium influx caused by endogenous oxidative stress

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28 September 2017

Ferroptosis: an iron-dependent form of nonapoptotic cell death

1 reference

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28 September 2017

Development of small-molecule probes that selectively kill cells induced to express mutant RAS

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Programmed cell death in animal development and disease

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28 September 2017

Modulatory profiling identifies mechanisms of small molecule-induced cell death.

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Distinct p53 transcriptional programs dictate acute DNA-damage responses and tumor suppression

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Selective killing of K-ras mutant cancer cells by small molecule inducers of oxidative stress

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28 September 2017

Bid-mediated mitochondrial damage is a key mechanism in glutamate-induced oxidative stress and AIF-dependent cell death in immortalized HT-22 hippocampal neurons

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Apoptosis and glutathione: beyond an antioxidant.

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28 September 2017

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28 September 2017

The cystine/cysteine cycle: a redox cycle regulating susceptibility versus resistance to cell death

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28 September 2017

RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels

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28 September 2017

What is responsible for the initiating chemistry of iron-mediated lipid peroxidation: an update

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28 September 2017

Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5.

1 reference

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Amino acid metabolism in mammalian cell cultures

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Oxytosis: A novel form of programmed cell death

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28 September 2017

Use of isogenic human cancer cells for high-throughput screening and drug discovery

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28 September 2017

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1 reference

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28 September 2017

Oxidative stress induces a form of programmed cell death with characteristics of both apoptosis and necrosis in neuronal cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887533

28 September 2017

A role for 12-lipoxygenase in nerve cell death caused by glutathione depletion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887533

28 September 2017

Glutathione deficiency is associated with impaired survival in HIV disease

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28 September 2017

The selenoenzyme phospholipid hydroperoxide glutathione peroxidase

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28 September 2017

Oncogenic RAS Mutants Confer Resistance of RMS13 Rhabdomyosarcoma Cells to Oxidative Stress-Induced Ferroptotic Cell Death

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31 May 2018

Identification of artesunate as a specific activator of ferroptosis in pancreatic cancer cells

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31 May 2018

Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression

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31 May 2018

The pantheon of the fallen: why are there so many forms of cell death?

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31 May 2018

Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence

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31 May 2018

System x(c)- and thioredoxin reductase 1 cooperatively rescue glutathione deficiency

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31 May 2018

Role for glutathione peroxidase-4 in brain development and neuronal apoptosis: specific induction of enzyme expression in reactive astrocytes following brain injury.

1 reference

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31 May 2018

Glutathione depletion is an early and calcium elevation is a late event of thymocyte apoptosis.

1 reference

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31 May 2018

Apoptosis or necrosis: intracellular levels of glutathione influence mode of cell death

1 reference

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31 May 2018

Immature cortical neurons are uniquely sensitive to glutamate toxicity by inhibition of cystine uptake

1 reference

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31 May 2018

Impairment of antioxidant defense via glutathione depletion sensitizes acute lymphoblastic leukemia cells for Smac mimetic-induced cell death

1 reference

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28 November 2018

Glutathione depletion by buthionine sulfoximine induces oxidative damage to DNA in organs of rabbits in vivo

1 reference

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28 November 2018

Intralysosomal iron chelation protects against oxidative stress-induced cellular damage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4887533

28 November 2018

Thioredoxin reductase reduces lipid hydroperoxides and spares alpha-tocopherol

1 reference

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28 November 2018

Effect of glutathione depletion on antitumor drug toxicity (apoptosis and necrosis) in U-937 human promonocytic cells. The role of intracellular oxidation

1 reference

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28 November 2018

Sulfasalazine, a potent suppressor of lymphoma growth by inhibition of the x(c)- cystine transporter: a new action for an old drug

1 reference

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28 November 2018

Salmonella induces macrophage death by caspase-1-dependent necrosis.

1 reference

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28 November 2018

Cystine deprivation induces oligodendroglial death: rescue by free radical scavengers and by a diffusible glial factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/27048822

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nutrition needs of mammalian cells in tissue culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/27048822

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The environment of the lipoxygenase iron binding site explored with novel hydroxypyridinone iron chelators

1 reference

https://pubmed.ncbi.nlm.nih.gov/27048822

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/27048822

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effect of levamisole and its sulfhydryl metabolite OMPI against cell death induced by glutathione depletion

1 reference

https://pubmed.ncbi.nlm.nih.gov/27048822

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Iron chelators inhibit human platelet aggregation, thromboxane A2 synthesis and lipoxygenase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/27048822

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of growth stimulation of L1210 cells by 2-mercaptoethanol in vitro. Role of the mixed disulfide of 2-mercaptoethanol and cysteine

1 reference

https://pubmed.ncbi.nlm.nih.gov/27048822

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of antioxidants on cultured human diploid fibroblasts exposed to cystine-free medium

1 reference

https://pubmed.ncbi.nlm.nih.gov/27048822

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The biosynthesis of cystine in human cell cultures

1 reference

https://pubmed.ncbi.nlm.nih.gov/27048822

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sorafenib-Induced Hepatocellular Carcinoma Cell Death Depends on Reactive Oxygen Species Production In Vitro and In Vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/27048822

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00018-016-2194-1

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27048822%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Dimensions Publication ID

0 references

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27048822%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27048822%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

ResearchGate publication ID

0 references

Sitelinks

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