(Q55884156)

1

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Kwok-Fai Lau

2

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Declan M. McLoughlin

3

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Janet Brownlees

4

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Steven Ackerley

5

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Christopher E. Shaw

7

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Christopher C. J. Miller

European Journal of Neuroscience

8

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language of work or name

English

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publication date

January 2001

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published in

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volume

13

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issue

2

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page(s)

241-247

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cites work

Hyperphosphorylated tau and neurofilament and cytoskeletal disruptions in mice overexpressing human p25, an activator of cdk5

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

The proteolytic fragments of the Alzheimer's disease-associated presenilin-1 form heterodimers and occur as a 100-150-kDa molecular mass complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

The cyclin-dependent kinase Cdk5 controls multiple aspects of axon patterning in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

Tyrosine phosphorylation and cadherin/catenin function

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

Regulation of exocytosis by cyclin-dependent kinase 5 via phosphorylation of Munc18

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

Presenilin-1 forms complexes with the cadherin/catenin cell-cell adhesion system and is recruited to intercellular and synaptic contacts

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

Regulation of beta-catenin signaling in the Wnt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

Regulation of N-cadherin-mediated adhesion by the p35-Cdk5 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

Neuronal Cdc2-like kinase (Nclk) binds and phosphorylates the retinoblastoma protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

Neurotoxicity induces cleavage of p35 to p25 by calpain

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

A brain-specific activator of cyclin-dependent kinase 5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

Expression of beta-catenin and the adenomatous polyposis coli tumour suppressor protein in mouse neocortical cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of beta-catenin, a component of the presenilin protein complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

Association of neurofilament proteins with neuronal Cdk5 activator

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

cdc2-like kinase from rat spinal cord specifically phosphorylates KSPXK motifs in neurofilament proteins: isolation and characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

Phosphorylation of the high molecular weight neurofilament protein (NF-H) by Cdk5 and p35

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

Precursor of cdk5 activator, the 23 kDa subunit of tau protein kinase II: its sequence and developmental change in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

The role of beta-catenin stability in mutant PS1-associated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

Presenilin 1 interaction in the brain with a novel member of the Armadillo family

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

Processing of cdk5 Activator p35 to Its Truncated Form (p25) by Calpain in Acutely Injured Neuronal Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X

The p35/Cdk5 kinase is a neuron-specific Rac effector that inhibits Pak1 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1460-9568.2001.01376.X