(Q56454444)

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Supramolecular hosts that recognize methyllysines and disrupt the interaction between a modified histone tail and its epigenetic reader protein

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scholarly article

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Supramolecular hosts that recognize methyllysines and disrupt the interaction between a modified histone tail and its epigenetic reader protein (English)

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object named as

Fraser Hof

9

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Robert E. Campbell

object named as

Robert E. Campbell

8

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author name string

Kevin D. Daze

1

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Thomas Pinter

2

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Cory S. Beshara

3

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Andreas Ibraheem

4

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Samuel A. Minaker

5

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Manuel C. F. Ma

6

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Rebecca J. M. Courtemanche

7

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publication date

2012

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Chemical Science

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3

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9

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2695

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The diverse functions of histone lysine methylation

1 reference

https://api.crossref.org/works/10.1039%2FC2SC20583A

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The many faces of histone lysine methylation

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Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells

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Cancer treatment of the future: inhibitors of histone methyltransferases

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Epigenetic therapy of cancer: past, present and future

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Protein methyltransferases as a target class for drug discovery

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21 January 2018

Structural basis for the product specificity of histone lysine methyltransferases

1 reference

https://api.crossref.org/works/10.1039%2FC2SC20583A

21 January 2018

Regulation of p53 activity through lysine methylation

1 reference

https://api.crossref.org/works/10.1039%2FC2SC20583A

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Biochemistry of anionic calix[n]arenes

1 reference

https://api.crossref.org/works/10.1039%2FC2SC20583A

21 January 2018

Biochemistry of the para-sulfonato-calix[n]arenes

1 reference

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Inclusion of naturally occurring amino acids in water soluble calix[4]arenes: a microcalorimetric and 1H NMR investigation supported by molecular modeling

1 reference

https://api.crossref.org/works/10.1039%2FC2SC20583A

21 January 2018

A simple calixarene recognizes post-translationally methylated lysine

1 reference

https://api.crossref.org/works/10.1039%2FC2SC20583A

21 January 2018

Recognition and Specificity Determinants of the Human Cbx Chromodomains

1 reference

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21 January 2018

Structure of the HP1 chromodomain bound to histone H3 methylated at lysine 9

1 reference

https://api.crossref.org/works/10.1039%2FC2SC20583A

21 January 2018

Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains

1 reference

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Recognition of trimethyllysine by a chromodomain is not driven by the hydrophobic effect

1 reference

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Recognition of amino acids by functionalized calixarenes.

1 reference

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21 January 2018

A shape-dependent hydrophobic effect for tetrazoles.

1 reference

https://api.crossref.org/works/10.1039%2FC2SC20583A

21 January 2018

A bacteria colony-based screen for optimal linker combinations in genetically encoded biosensors

1 reference

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Genetically encoded fluorescent reporters of histone methylation in living cells

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How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers

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Using physical chemistry to differentiate nicotinic from cholinergic agonists at the nicotinic acetylcholine receptor

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Finding Inspiration in the Protein Data Bank to Chemically Antagonize Readers of the Histone Code

1 reference

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Pharmacophore screening of the protein data bank for specific binding site chemistry.

1 reference

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21 January 2018

Small-Molecule Ligands of Methyl-Lysine Binding Proteins

1 reference

https://api.crossref.org/works/10.1039%2FC2SC20583A

21 January 2018

A small molecule receptor that selectively recognizes trimethyl lysine in a histone peptide with native protein-like affinity

1 reference

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21 January 2018

Epigenetic protein families: a new frontier for drug discovery

1 reference

https://api.crossref.org/works/10.1039%2FC2SC20583A

21 January 2018

Screening for inhibitors of low-affinity epigenetic peptide-protein interactions: an AlphaScreen-based assay for antagonists of methyl-lysine binding proteins

1 reference

https://api.crossref.org/works/10.1039%2FC2SC20583A

21 January 2018

Chemical Sensors Based on Cyclodextrin Derivatives.

1 reference

https://api.crossref.org/works/10.1039%2FC2SC20583A

21 January 2018

A Fluorescence-Based Supramolecular Tandem Assay for Monitoring Lysine Methyltransferase Activity in Homogeneous Solution

1 reference

https://api.crossref.org/works/10.1039%2FC2SC20583A

21 January 2018

Antibody-free reading of the histone code using a simple chemical sensor array

1 reference

https://api.crossref.org/works/10.1039%2FC2SC20583A

21 January 2018

Synthesis of new trisulfonated calix[4]arenes functionalized at the upper rim, and their complexation with the trimethyllysine epigenetic mark

1 reference

https://api.crossref.org/works/10.1039%2FC2SC20583A

21 January 2018

Identifiers

10.1039/C2SC20583A

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