(Q57004702)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25345908%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

title

Modeling the effects of commonly used drugs on human metabolism (English)

1 reference

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21 February 2020

3

1 reference

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21 February 2020

Ines Thiele

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25345908%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

author name string

Swagatika Sahoo

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25345908%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Hulda S Haraldsdóttir

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25345908%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

language of work or name

English

0 references

publication date

21 November 2014

1 reference

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21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25345908%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

volume

282

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25345908%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

page(s)

297-317

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21 February 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25345908%20AND%20SRC:MED&resulttype=core&format=json

Dietary Effects on Drug Metabolism and Transport

21 February 2020

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Influence of diet and nutritional status on drug metabolism

21 January 2018

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Statin precipitated lactic acidosis?

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Challenges in diagnosing a metabolic disorder: error of pyruvate metabolism or drug induced?

21 January 2018

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A community-driven global reconstruction of human metabolism.

21 January 2018

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Global reconstruction of the human metabolic network based on genomic and bibliomic data

21 January 2018

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A genome-scale modeling approach to study inborn errors of liver metabolism: toward an in silico patient

21 January 2018

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Predicting metabolic biomarkers of human inborn errors of metabolism

21 January 2018

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Drug off-target effects predicted using structural analysis in the context of a metabolic network model

21 January 2018

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Reconstruction of genome-scale active metabolic networks for 69 human cell types and 16 cancer types using INIT

21 January 2018

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Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase

21 January 2018

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Predicting selective drug targets in cancer through metabolic networks.

21 January 2018

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Integrative genome-scale metabolic analysis of Vibrio vulnificus for drug targeting and discovery

21 January 2018

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Large-scale in silico modeling of metabolic interactions between cell types in the human brain

21 January 2018

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Integration of clinical data with a genome-scale metabolic model of the human adipocyte

21 January 2018

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Reconstruction of genome-scale metabolic models for 126 human tissues using mCADRE

21 January 2018

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HepatoNet1: a comprehensive metabolic reconstruction of the human hepatocyte for the analysis of liver physiology

21 January 2018

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Integrating cellular metabolism into a multiscale whole-body model

21 January 2018

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Metabolism and drug interactions of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in transplant patients: are the statins mechanistically similar?

21 January 2018

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A frameshift variant of CYP2C8 was identified in a patient who suffered from rhabdomyolysis after administration of cerivastatin

21 January 2018

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Metabolic properties of the acid and lactone forms of HMG-CoA reductase inhibitors

21 January 2018

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Effects of acid and lactone forms of eight HMG-CoA reductase inhibitors on CYP-mediated metabolism and MDR1-mediated transport.

21 January 2018

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Clinical pharmacokinetics of pravastatin: mechanisms of pharmacokinetic events

21 January 2018

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Clinical pharmacokinetics and pharmacodynamics of torasemide

21 January 2018

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Expression studies and functional characterization of renal human organic anion transporter 1 isoforms.

21 January 2018

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Cyclosporin metabolism in transplant patients

21 January 2018

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Alternative cyclosporine metabolic pathways and toxicity

21 January 2018

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Effect of CYP3A5 polymorphism on tacrolimus metabolic clearance in vitro.

21 January 2018

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The absorption site of cyclosporin in the human gastrointestinal tract

21 January 2018

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The site-specific transport and metabolism of tacrolimus in rat small intestine

21 January 2018

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Ibuprofen: pharmacology, efficacy and safety

21 January 2018

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Acetaminophen (paracetamol) is a selective cyclooxygenase-2 inhibitor in man.

21 January 2018

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Human UDP-glucuronosyltransferases: metabolism, expression, and disease

21 January 2018

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Confirmation that cytochrome P450 2C8 (CYP2C8) plays a minor role in (S)-(+)- and (R)-(-)-ibuprofen hydroxylation in vitro

21 January 2018

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Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule?

21 January 2018

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The mode of action and clinical pharmacology of gliclazide: a review

21 January 2018

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21 January 2018

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Clinical pharmacokinetics and pharmacodynamics of allopurinol and oxypurinol

21 January 2018

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Identification of the human cytochromes P450 catalysing the rate-limiting pathways of gliclazide elimination

21 January 2018

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The metabolism of gliclazide in man.

21 January 2018

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First-pass metabolism of midazolam by the human intestine.

21 January 2018

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Concentrative nucleoside transporters (CNTs) in epithelia: from absorption to cell signaling

21 January 2018

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The promiscuous binding of pharmaceutical drugs and their transporter-mediated uptake into cells: what we (need to) know and how we can do so.

21 January 2018

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Organic anion transporting polypeptide 1B1: a genetically polymorphic transporter of major importance for hepatic drug uptake

21 January 2018

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What is flux balance analysis?

21 January 2018

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Grapefruit juice enhances intestinal absorption of the P-glycoprotein substrate talinolol

21 January 2018

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Computationally efficient flux variability analysis

21 January 2018

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A modern approach to the treatment of mitochondrial disease

21 January 2018

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Coenzyme Q10 and statins: biochemical and clinical implications

21 January 2018

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Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2.0

21 January 2018

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A compendium of inborn errors of metabolism mapped onto the human metabolic network

21 January 2018

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Rhabdomyolysis and renal injury with lovastatin use. Report of two cases in cardiac transplant recipients

21 January 2018

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Gut Pharmacomicrobiomics: the tip of an iceberg of complex interactions between drugs and gut-associated microbes

21 January 2018

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Brassica vegetables increase and apiaceous vegetables decrease cytochrome P450 1A2 activity in humans: changes in caffeine metabolite ratios in response to controlled vegetable diets

21 January 2018

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Dietary influences on the kinetics of antipyrine and aminopyrine in human subjects

21 January 2018

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Pharmacological interactions of statins.

21 January 2018

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Efficacy and safety of atorvastatin after pediatric heart transplantation

21 January 2018

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Efficacy and drug interactions of the new HMG-CoA reductase inhibitors cerivastatin and atorvastatin in CsA-treated renal transplant recipients

21 January 2018

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Genetic risk factors associated with lipid-lowering drug-induced myopathies

21 January 2018

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Genetic predisposition to statin myopathy

21 January 2018

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Torsemide renal clearance and genetic variation in luminal and basolateral organic anion transporters

21 January 2018

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Pharmacogenomics knowledge for personalized medicine

21 January 2018

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DrugBank 3.0: a comprehensive resource for 'omics' research on drugs

21 January 2018

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HMDB: the Human Metabolome Database

21 January 2018

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The ChEBI reference database and ontology for biologically relevant chemistry: enhancements for 2013

21 January 2018

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Entrez Gene: gene-centered information at NCBI

21 January 2018

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Reorganizing the protein space at the Universal Protein Resource (UniProt)

21 January 2018

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BRENDA, the enzyme information system in 2011

21 January 2018

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A protocol for generating a high-quality genome-scale metabolic reconstruction

21 January 2018

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Revisiting dietary cholesterol recommendations: does the evidence support a limit of 300 mg/d?

21 January 2018

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rBioNet: A COBRA toolbox extension for reconstructing high-quality biochemical networks.

21 January 2018

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Predicting the impact of diet and enzymopathies on human small intestinal epithelial cells

21 January 2018

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The effects of alternate optimal solutions in constraint-based genome-scale metabolic models

21 January 2018

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Comparison of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) as inhibitors of cytochrome P450 2C8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13128

Differential interaction of 3-hydroxy-3-methylglutaryl-coa reductase inhibitors with ABCB1, ABCC2, and OATP1B1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.13128

Influence of drug transporter polymorphisms on pravastatin pharmacokinetics in humans

21 January 2018

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Clinical pharmacokinetics of fluvastatin

21 January 2018

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Metabolic fate of pitavastatin, a new inhibitor of HMG-CoA reductase: human UDP-glucuronosyltransferase enzymes involved in lactonization

21 January 2018

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Pitavastatin: a review of its use in the management of hypercholesterolaemia or mixed dyslipidaemia

21 January 2018

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A review of the pharmacologic and pharmacokinetic aspects of rosuvastatin

21 January 2018

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Novel statins: pharmacological and clinical results.

21 January 2018

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Clinical pharmacokinetics of losartan

21 January 2018

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In vitro metabolism of midazolam, triazolam, nifedipine, and testosterone by human liver microsomes and recombinant cytochromes p450: role of cyp3a4 and cyp3a5.

21 January 2018

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https://api.crossref.org/works/10.1111%2FFEBS.13128

Regioselective and stereoselective metabolism of ibuprofen by human cytochrome P450 2C.

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1111/FEBS.13128

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25345908%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference