(Q57082587)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25403101%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

title

A critical role for murine transferrin receptor 2 in erythropoiesis during iron restriction (English)

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22 February 2020

1

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22 February 2020

Gautam Rishi

3

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22 February 2020

Cameron J McDonald

5

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22 February 2020

Therese Vu

7

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22 February 2020

John D Hooper

8

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22 February 2020

Carlos López Otín

11

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22 February 2020

Nathan V Subramaniam

12

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22 February 2020

4

Lesa Ostini

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22 February 2020

9

Gloria Velasco

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22 February 2020

2

Eriza S Secondes

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22 February 2020

author name string

Steven W Lane

6

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22 February 2020

Andrew J Ramsay

10

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22 February 2020

language of work or name

English

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publication date

17 November 2014

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British Journal of Haematology

22 February 2020

published in

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22 February 2020

volume

168

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22 February 2020

issue

6

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22 February 2020

page(s)

891-901

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BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism

22 February 2020

cites work

1 reference

Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression

21 January 2018

1 reference

Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis.

21 January 2018

1 reference

Erythropoietin: multiple targets, actions, and modifying influences for biological and clinical consideration

21 January 2018

1 reference

The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice

21 January 2018

1 reference

Resolving the distinct stages in erythroid differentiation based on dynamic changes in membrane protein expression during erythropoiesis

21 January 2018

1 reference

Molecular basis of iron-loading disorders.

21 January 2018

1 reference

The serine protease TMPRSS6 is required to sense iron deficiency

21 January 2018

1 reference

Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)

21 January 2018

1 reference

Tmprss6 is a genetic modifier of the Hfe-hemochromatosis phenotype in mice

21 January 2018

1 reference

Mouse strain differences determine severity of iron accumulation in Hfe knockout model of hereditary hemochromatosis

21 January 2018

1 reference

Membrane-bound serine protease matriptase-2 (Tmprss6) is an essential regulator of iron homeostasis

21 January 2018

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Transferrin receptor 2 is a component of the erythropoietin receptor complex and is required for efficient erythropoiesis.

21 January 2018

1 reference

Iron sequestration and anemia of inflammation

21 January 2018

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Reducing TMPRSS6 ameliorates hemochromatosis and β-thalassemia in mice

21 January 2018

1 reference

Regulation of erythropoietin production

21 January 2018

1 reference

Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver

21 January 2018

1 reference

Identification of erythroferrone as an erythroid regulator of iron metabolism

21 January 2018

1 reference

Expression of transferrin receptor 2 in normal and neoplastic hematopoietic cells

21 January 2018

1 reference

Molecular evidence for transferrin receptor 2 expression in all FAB subtypes of acute myeloid leukemia

21 January 2018

1 reference

Severe microcytic anemia but increased erythropoiesis in mice lacking Hfe or Tfr2 and Tmprss6

21 January 2018

1 reference

Increased iron stores correlate with worse disease outcomes in a mouse model of schistosomiasis infection

21 January 2018

1 reference

Lack of the bone morphogenetic protein BMP6 induces massive iron overload

21 January 2018

1 reference

The erythroid function of transferrin receptor 2 revealed by Tmprss6 inactivation in different models of transferrin receptor 2 knockout mice.

21 January 2018

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Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

21 January 2018

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Hepcidin is decreased in TFR2 hemochromatosis

21 January 2018

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The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation

21 January 2018

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Enhanced erythropoiesis in Hfe-KO mice indicates a role for Hfe in the modulation of erythroid iron homeostasis

21 January 2018

1 reference

Matriptase-2 mutations in iron-refractory iron deficiency anemia patients provide new insights into protease activation mechanisms.

21 January 2018

1 reference

An RNAi therapeutic targeting Tmprss6 decreases iron overload in Hfe(-/-) mice and ameliorates anemia and iron overload in murine β-thalassemia intermedia

21 January 2018

1 reference

The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin

21 January 2018

1 reference

High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin

21 January 2018

1 reference

Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells

21 January 2018

1 reference

Suppression of the hepcidin-encoding gene Hamp permits iron overload in mice lacking both hemojuvelin and matriptase-2/TMPRSS6

21 January 2018

1 reference

First phenotypic description of transferrin receptor 2 knockout mouse, and the role of hepcidin.

21 January 2018

1 reference

Targeted disruption of the hepatic transferrin receptor 2 gene in mice leads to iron overload.

21 January 2018

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Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload.

21 January 2018

1 reference

Genetic variation in Mon1a affects protein trafficking and modifies macrophage iron loading in mice

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/BJH.13225

1 reference

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22 February 2020

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