(Q57189276)

2

0 references

Santosh K. Padhi

3

0 references

Sebastian Schätzle

4

0 references

Uwe T. Bornscheuer

Advanced Synthesis & Catalysis

5

0 references

publication date

September 2011

0 references

published in

0 references

volume

353

0 references

issue

13

0 references

page(s)

2191-2215

0 references

cites work

An enzyme library approach to biocatalysis: development of nitrilases for enantioselective production of carboxylic acid derivatives

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https://api.crossref.org/works/10.1002%2FADSC.201100446

Exploring nitrilase sequence space for enantioselective catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Rational assignment of key motifs for function guides in silico enzyme identification

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Protein structure prediction on the Web: a case study using the Phyre server

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

The SWISS-MODEL Repository and associated resources

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Protein Modeling by E-mail

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Protein structure prediction and analysis using the Robetta server.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Improving physical realism, stereochemistry, and side-chain accuracy in homology modeling: Four approaches that performed well in CASP8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Basic local alignment search tool

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

A new bioinformatics analysis tools framework at EMBL-EBI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Clustal W and Clustal X version 2.0

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Biocatalytic asymmetric synthesis of chiral amines from ketones applied to sitagliptin manufacture

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Laboratory evolution of stereoselective enzymes: a prolific source of catalysts for asymmetric reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Status of protein engineering for biocatalysts: how to design an industrially useful biocatalyst

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Finding better protein engineering strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

The synthesis of chiral cyanohydrins by oxynitrilases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Oxynitrilases for asymmetric C-C bond formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Isoenzymes of Pig-Liver Esterase Reveal Striking Differences in Enantioselectivities

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Measurement of in situ activities of nonphotosynthetic microorganisms in aquatic and terrestrial habitats

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

A molecular view of microbial diversity and the biosphere

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Functional metagenomics for enzyme discovery: challenges to efficient screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Metagenomic era for biocatalyst identification

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Isolation and characterization of cold-active family VIII esterases from an arctic soil metagenome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Screening and identification of a novel esterase EstPE from a metagenomic DNA library

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Isolation and characterization of a GDSL esterase from the metagenome of a marine sponge-associated bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Indication for a new lipolytic enzyme family: isolation and characterization of two esterases from a metagenomic library

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

A novel cold-active xylanase gene from the environmental DNA of goat rumen contents: direct cloning, expression and enzyme characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Identification and characterization of a novel xylanase derived from a rice straw degrading enrichment culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Cloning and functional characterization of a novel endo-β-1,4-glucanase gene from a soil-derived metagenomic library

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

A novel metagenome-derived beta-galactosidase: gene cloning, overexpression, purification and characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Environmental genome shotgun sequencing of the Sargasso Sea

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Cloning, expression, and characterization of a Baeyer-Villiger monooxygenase from Pseudomonas fluorescens DSM 50106 in E. coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Kinetic resolution of 4-hydroxy-2-ketones catalyzed by a Baeyer-Villiger monooxygenase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Genome mining for the discovery of new nitrilases in filamentous fungi

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Identification and characterization of a novel L-amino acid ligase from Photorhabdus luminescens subsp. laumondii TT01.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Diversity and biocatalytic potential of epoxide hydrolases identified by genome analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Production and characterization of a thermostable alcohol dehydrogenase that belongs to the aldo-keto reductase superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Discovery of a thermostable Baeyer-Villiger monooxygenase by genome mining

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Genome mining approach for the discovery of novel cytochrome P450 biocatalysts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Genome mining and biosynthesis of fumitremorgin-type alkaloids in ascomycetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Engineering of Candida antarctica lipase B for hydrolysis of bulky carboxylic acid esters

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Combined use of experimental and computational screens to characterize protein stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Rapid evolution of a protein in vitro by DNA shuffling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Saturation mutagenesis by mutagenic oligonucleotide-directed PCR amplification (Mod-PCR).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Ultrahigh-throughput FACS-based screening for directed enzyme evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Pooling for improved screening of combinatorial libraries for directed evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Simulation modeling of pooling for combinatorial protein engineering.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

In the light of directed evolution: pathways of adaptive protein evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Directed enzyme evolution via small and effective neutral drift libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Protein engineers turned evolutionists

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Increasing the precision of comparative models with YASARA NOVA-a self-parameterizing force field

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Making optimal use of empirical energy functions: force-field parameterization in crystal space

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Atomistic insights into the inhibition of cysteine proteases: first QM/MM calculations clarifying the regiospecificity and the inhibition potency of epoxide- and aziridine-based inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Complete Inversion of Enantioselectivity towards Acetylated Tertiary Alcohols by a Double Mutant of aBacillus Subtilis Esterase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Darwinian evolution can follow only very few mutational paths to fitter proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Constructing and analyzing the fitness landscape of an experimental evolutionary process

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Improving catalytic function by ProSAR-driven enzyme evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

The consensus concept for thermostability engineering of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Thermostable variants constructed via the structure-guided consensus method also show increased stability in salts solutions and homogeneous aqueous-organic media

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

The alpha/beta-hydrolase fold 3DM database (ABHDB) as a tool for protein engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Natural diversity to guide focused directed evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Thermostabilization of an esterase by alignment-guided focussed directed evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Improving thermostability of papain through structure-based protein engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Thermostabilization of Bacillus circulans xylanase via computational design of a flexible surface cavity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Improving thermostability and catalytic activity of pyranose 2-oxidase from Trametes multicolor by rational and semi-rational design

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Rational design of catechol-2, 3-dioxygenase for improving the enzyme characteristics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Enhancing thermostability of Escherichia coli phytase AppA2 by error-prone PCR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Enhancing thermostability of a Rhizomucor miehei lipase by engineering a disulfide bond and displaying on the yeast cell surface.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Biocatalytic production of (S)-4-bromo-3-hydroxybutyrate and structurally related chemicals and their applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Enhanced thermostability of methyl parathion hydrolase from Ochrobactrum sp. M231 by rational engineering of a glycine to proline mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Improvement of Bacillus circulans beta-amylase activity attained using the ancestral mutation method.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Engineering of Clostridium phytofermentans Endoglucanase Cel5A for improved thermostability

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

A family of thermostable fungal cellulases created by structure-guided recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Engineering thermal stability of L-asparaginase by in vitro directed evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Knowledge-guided laboratory evolution of protein thermolability

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Computational design-based molecular engineering of the glycosyl hydrolase family 11 B. subtilis XynA endoxylanase improves its acid stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Modification of pancreatic lipase properties by directed molecular evolution.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Redesign the α/β fold to enhance the stability of mannanase Man23 from Bacillus subtilis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Improving biocatalyst performance by integrating statistical methods into protein engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Computational structure-based redesign of enzyme activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

A directed evolution design of a GCG-specific DNA hemimethylase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Glyphosate Resistance by Engineering the Flavoenzyme Glycine Oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Engineering of choline oxidase from Arthrobacter nicotianae for potential use as biological bleach in detergents

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Stereoselective C-C bond formation catalysed by engineered carboxymethylproline synthases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Redesigning the active site of transaldolase TalB from Escherichia coli: new variants with improved affinity towards nonphosphorylated substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Evolution in reverse: engineering a D-xylose-specific xylose reductase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Protein engineering of toluene monooxygenases for synthesis of chiral sulfoxides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Directed evolution of galactose oxidase: generation of enantioselective secondary alcohol oxidases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Manipulating the stereoselectivity of limonene epoxide hydrolase by directed evolution based on iterative saturation mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Directed evolution of aniline dioxygenase for enhanced bioremediation of aromatic amines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Broadening the cofactor specificity of a thermostable alcohol dehydrogenase using rational protein design introduces novel kinetic transient behavior.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Structure-based redesign of cofactor binding in putrescine oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Reversed enantioselectivity of diisopropyl fluorophosphatase against organophosphorus nerve agents by rational design

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Creation of a pair of stereochemically complementary biocatalysts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Alteration of the diastereoselectivity of 3-methylaspartate ammonia lyase by using structure-based mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Engineering enzyme specificity using computational design of a defined-sequence library

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Redesigning dehalogenase access tunnels as a strategy for degrading an anthropogenic substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Most efficient cocaine hydrolase designed by virtual screening of transition states

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Directed evolution of 2-keto-3-deoxy-6-phosphogalactonate aldolase to replace 3-deoxy-D-arabino-heptulosonic acid 7-phosphate synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Mutational analysis of phenylalanine ammonia lyase to improve reactions rates for various substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Directed evolution of Methanococcus jannaschii citramalate synthase for biosynthesis of 1-propanol and 1-butanol by Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Directed evolution of a lysosomal enzyme with enhanced activity at neutral pH by mammalian cell-surface display

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Engineering of glycerol dehydrogenase for improved activity towards 1, 3-butanediol

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Enhanced expression and purification of fungal galactose oxidase in Escherichia coli and use for analysis of a saturation mutagenesis library

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Site-directed mutagenesis of the Anabaena sp. strain PCC 7120 nitrogenase active site to increase photobiological hydrogen production

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Design and signaling mechanism of light-regulated histidine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Engineering of a fungal beta-galactosidase to remove product inhibition by galactose.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Crystallization and preliminary X-ray crystallographic studies of ω-transaminase from Vibrio fluvialis JS17.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Redesigning the substrate specificity of omega-aminotransferase for the kinetic resolution of aliphatic chiral amines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Sitagliptin manufacture: a compelling tale of green chemistry, process intensification, and industrial asymmetric catalysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Enzymatic Asymmetric Synthesis of Enantiomerically Pure Aliphatic, Aromatic and Arylaliphatic Amines with (R)-Selective Amine Transaminases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Asymmetric bioreduction of activated C=C bonds using enoate reductases from the old yellow enzyme family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Site-saturation mutagenesis of tryptophan 116 of Saccharomyces pastorianus old yellow enzyme uncovers stereocomplementary variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Focused directed evolution of pentaerythritol tetranitrate reductase by using automated anaerobic kinetic screening of site-saturated libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

A site-saturated mutagenesis study of pentaerythritol tetranitrate reductase reveals that residues 181 and 184 influence ligand binding, stereochemistry and reactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Enzymatic synthesis of optically active tertiary alcohols: expanding the biocatalysis toolbox.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

A molecular mechanism of enantiorecognition of tertiary alcohols by carboxylesterases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Highly enantioselective kinetic resolution of two tertiary alcohols using mutants of an esterase from Bacillus subtilis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Highly Enantioselective Synthesis of Arylaliphatic Tertiary Alcohols using Mutants of an Esterase fromBacillus subtilis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Deracemization of alpha-methylbenzylamine using an enzyme obtained by in vitro evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Directed evolution of an amine oxidase for the preparative deracemisation of cyclic secondary amines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

A chemo-enzymatic route to enantiomerically pure cyclic tertiary amines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Enantioselective biocatalytic oxidative desymmetrization of substituted pyrrolidines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Biocatalysis by dehalogenating enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Substrate specificity of haloalkane dehalogenases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

One pot 'click' reactions: tandem enantioselective biocatalytic epoxide ring opening and [3+2] azide alkyne cycloaddition

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Biodegradation of 1,2,3-trichloropropane through directed evolution and heterologous expression of a haloalkane dehalogenase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Improved catalytic properties of halohydrin dehalogenase by modification of the halide-binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Rational design of potent sialidase-based inhibitors of influenza virus replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Directed evolution of N-acetylneuraminic acid aldolase to catalyze enantiomeric aldol reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Modifying the stereochemistry of an enzyme-catalyzed reaction by directed evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Directed evolution of an industrial biocatalyst: 2-deoxy-D-ribose 5-phosphate aldolase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Development of an efficient, scalable, aldolase-catalyzed process for enantioselective synthesis of statin intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

The cytochrome P450 engineering database: Integration of biochemical properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

DWARF--a data warehouse system for analyzing protein families.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

The Cytochrome P450 Engineering Database: a navigation and prediction tool for the cytochrome P450 protein family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Rational design of a minimal and highly enriched CYP102A1 mutant library with improved regio-, stereo- and chemoselectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Engineering cytochrome P450 BM-3 for oxidation of polycyclic aromatic hydrocarbons

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

A novel semi-biosynthetic route for artemisinin production using engineered substrate-promiscuous P450(BM3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Application of molecular modeling for prediction of substrate specificity in cytochrome P450 1A2 mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Preparative use of isolated CYP102 monooxygenases -- a critical appraisal

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Engineering and analysis of a self-sufficient biosynthetic cytochrome P450 PikC fused to the RhFRED reductase domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

LICRED: a versatile drop-in vector for rapid generation of redox-self-sufficient cytochrome P450s

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Changing the substrate specificity of P450cam towards diphenylmethane by semi-rational enzyme engineering

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Molecular recognition in (+)-alpha-pinene oxidation by cytochrome P450cam

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Enantioselective epoxidation of terminal alkenes to (R)- and (S)-epoxides by engineered cytochromes P450 BM-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Identification of a novel self-sufficient styrene monooxygenase from Rhodococcus opacus 1CP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

In vitro evolution of styrene monooxygenase from Pseudomonas putida CA-3 for improved epoxide synthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Ligation independent cloning (LIC) as a rapid route to families of recombinant biocatalysts from sequenced prokaryotic genomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Insights into sequence-activity relationships amongst Baeyer-Villiger monooxygenases as revealed by the intragenomic complement of enzymes from Rhodococcus jostii RHA1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Crystal structure of a Baeyer-Villiger monooxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Crystal structures of cyclohexanone monooxygenase reveal complex domain movements and a sliding cofactor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Laboratory evolution of robust and enantioselective Baeyer-Villiger monooxygenases for asymmetric catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Directed evolution of a Baeyer-Villiger monooxygenase to enhance enantioselectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Directed evolution as a method to create enantioselective cyclohexanone monooxygenases for catalysis in Baeyer-Villiger reactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Microbial Baeyer-Villiger oxidation: stereopreference and substrate acceptance of cyclohexanone monooxygenase mutants prepared by directed evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Towards practical Baeyer-Villiger-monooxygenases: design of cyclohexanone monooxygenase mutants with enhanced oxidative stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Identifying determinants of NADPH specificity in Baeyer-Villiger monooxygenases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

A light-driven stereoselective biocatalytic oxidation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Self-sufficient Baeyer-Villiger monooxygenases: effective coenzyme regeneration for biooxygenation by fusion engineering.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Recent developments in the application of Baeyer-Villiger monooxygenases as biocatalysts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

ROSETTA3: an object-oriented software suite for the simulation and design of macromolecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

De novo computational design of retro-aldol enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Kemp elimination catalysts by computational enzyme design

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Optimization of the In-Silico-Designed Kemp Eliminase KE70 by Computational Design and Directed Evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Development of an Escherichia coli whole cell biocatalyst for the production of L-amino acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Microbial production of fatty-acid-derived fuels and chemicals from plant biomass

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

QM/MM Methods for Biological Systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Directed evolution of enantioselective enzymes: iterative cycles of CASTing for probing protein-sequence space

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Iterative saturation mutagenesis on the basis of B factors as a strategy for increasing protein thermostability

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Directed evolution of an amine oxidase possessing both broad substrate specificity and high enantioselectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Greatly reduced amino acid alphabets in directed evolution: making the right choice for saturation mutagenesis at homologous enzyme positions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Directed evolution of cyclohexanone monooxygenases: enantioselective biocatalysts for the oxidation of prochiral thioethers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Directed evolution of hydrolases for prevention of G-type nerve agent intoxication

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

A template-based mnemonic for monoamine oxidase (MAO-N) catalyzed reactions and its application to the chemo-enzymatic deracemisation of the alkaloid (±)-crispine A

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Highly Stereoselective Synthesis of Substituted Prolyl Peptides Using a Combination of Biocatalytic Desymmetrization and Multicomponent Reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Increasing the stability of an enzyme toward hostile organic solvents by directed evolution based on iterative saturation mutagenesis using the B-FIT method

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Directed evolution of an enantioselective lipase with broad substrate scope for hydrolysis of alpha-substituted esters

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Inverting the enantioselectivity of P450pyr monooxygenase by directed evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Engineering allosteric regulation into the hinge region of a circularly permuted TEM-1 beta-lactamase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446

Conversion of Pyruvate Decarboxylase into an Enantioselective Carboligase with Biosynthetic Potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FADSC.201100446