(Q57539960)

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Differential Expression of Aggrecanase and Matrix Metalloproteinase Activity in Chondrocytes Isolated from Bovine and Porcine Articular Cartilage

scientific article published in Journal of Biological Chemistry

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scholarly article

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6 December 2019

Differential expression of aggrecanase and matrix metalloproteinase activity in chondrocytes isolated from bovine and porcine articular cartilage (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9804828%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

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Clare E. Hughes

1

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6 December 2019

Christopher B Little

2

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6 December 2019

5

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6 December 2019

4

object named as

E Bartnik

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6 December 2019

author name string

F H Büttner

3

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6 December 2019

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publication date

1 November 1998

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6 December 2019

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7

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Journal of Biological Chemistry

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6 December 2019

273

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6 December 2019

30576-30582

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6 December 2019

46

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6 December 2019

N-terminal sequence of proteoglycan fragments isolated from medium of interleukin-1-treated articular-cartilage cultures. Putative site(s) of enzymic cleavage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.46.30576

21 January 2018

Mechanism of catabolism of aggrecan by articular cartilage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.46.30576

21 January 2018

Aggrecan is degraded by matrix metalloproteinases in human arthritis. Evidence that matrix metalloproteinase and aggrecanase activities can be independent

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.46.30576

21 January 2018

Aggrecan degradation in human cartilage. Evidence for both matrix metalloproteinase and aggrecanase activity in normal, osteoarthritic, and rheumatoid joints

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.46.30576

21 January 2018

The structure of aggrecan fragments in human synovial fluid. Evidence for the involvement in osteoarthritis of a novel proteinase which cleaves the Glu 373-Ala 374 bond of the interglobular domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.46.30576

21 January 2018

Neutrophil collagenase (MMP-8) cleaves at the aggrecanase site E373-A374 in the interglobular domain of cartilage aggrecan

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.46.30576

21 January 2018

Membrane type 1 matrix metalloproteinase (MT1-MMP) cleaves the recombinant aggrecan substrate rAgg1mut at the 'aggrecanase' and the MMP sites. Characterization of MT1-MMP catabolic activities on the interglobular domain of aggrecan

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.46.30576

21 January 2018

Monoclonal antibodies that specifically recognize neoepitope sequences generated by 'aggrecanase' and matrix metalloproteinase cleavage of aggrecan: application to catabolism in situ and in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.46.30576

21 January 2018

Cell-mediated catabolism of aggrecan. Evidence that cleavage at the "aggrecanase" site (Glu373-Ala374) is a primary event in proteolysis of the interglobular domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.46.30576

21 January 2018

Development of a cleavage-site-specific monoclonal antibody for detecting metalloproteinase-derived aggrecan fragments: detection of fragments in human synovial fluids

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.46.30576

21 January 2018

Utilization of a Recombinant Substrate rAgg1 to Study the Biochemical Properties of Aggrecanase in Cell Culture Systems

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.46.30576

21 January 2018

Extracellular matrix metabolism by chondrocytes III. Modulation of proteoglycan synthesis by extracellular levels of proteoglycan in cartilage cells in culture

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.46.30576

21 January 2018

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.46.30576

21 January 2018

Catabolism of aggrecan by explant cultures of human articular cartilage in the presence of retinoic acid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.46.30576

21 January 2018

Interleukin 1 preferentially stimulates the production of tissue-type plasminogen activator by human articular chondrocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.46.30576

21 January 2018

Inhibition of interleukin 1-stimulated cartilage proteoglycan degradation by a lipophilic inactivator of cysteine endopeptidases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.46.30576

21 January 2018

Inhibition of bovine nasal cartilage degradation by selective matrix metalloproteinase inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.46.30576

21 January 2018

The structure of aggrecan fragments in human synovial fluid. Evidence that aggrecanase mediates cartilage degradation in inflammatory joint disease, joint injury, and osteoarthritis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.46.30576

21 January 2018

Extracellular matrix metabolism by chondrocytes. VI. Concomitant depression by exogenous levels of proteoglycan of collagen and proteoglycan synthesis by chondrocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.46.30576

21 January 2018

Modulation by retinoic acid and corticosteroids of collagenase production by rabbit synovial fibroblasts treated with phorbol myristate acetate or poly(ethylene glycol)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.46.30576

21 January 2018

Inhibition of cartilage proteoglycan release by a specific inactivator of cathepsin B and an inhibitor of matrix metalloproteinases. Evidence for two converging pathways of chondrocyte-mediated proteoglycan degradation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.46.30576

21 January 2018

Effects of proteinase inhibitors on aggrecan catabolism in chondrocyte cultures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.46.30576

21 January 2018

Inhibition of cartilage degradation and changes in physical properties induced by IL-1beta and retinoic acid using matrix metalloproteinase inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.46.30576

21 January 2018

The interglobular domain of cartilage aggrecan is cleaved by hemorrhagic metalloproteinase HT-d (atrolysin C) at the matrix metalloproteinase and aggrecanase sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.46.30576

21 January 2018

Identifiers

10.1074/JBC.273.46.30576

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9804828%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9804828%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

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