(Q57782667)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23448241%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

title

Substituted purine and 7-deazapurine compounds as modulators of epigenetic enzymes: a patent evaluation (WO2012075381) (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23448241%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23448241%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Clarissa Gerhäuser

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23448241%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

author name string

Dirk Kuck

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23448241%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Christian Kliem

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23448241%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

language of work or name

English

0 references

publication date

1 March 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23448241%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Therapeutic Patents

24 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23448241%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

volume

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23448241%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23448241%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

page(s)

537-543

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23448241%20AND%20SRC:MED&resulttype=core&format=json

Exploring and explaining epigenetic effects.

24 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2013.776040

Epigenetic protein families: a new frontier for drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2013.776040

Protein methyltransferases as a target class for drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2013.776040

Emerging epigenetic targets and therapies in cancer medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2013.776040

The diverse functions of Dot1 and H3K79 methylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2013.776040

MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2013.776040

MLL translocations, histone modifications and leukaemia stem-cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2013.776040

The MLL recombinome of acute leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2013.776040

hDOT1L links histone methylation to leukemogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2013.776040

Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2013.776040

Selective Inhibitors of Histone Methyltransferase DOT1L: Design, Synthesis, and Crystallographic Studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2013.776040

Conformational adaptation drives potent, selective and durable inhibition of the human protein methyltransferase DOT1L

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2013.776040

Synthesis and structure-activity relationship investigation of adenosine-containing inhibitors of histone methyltransferase DOT1L

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2013.776040

A decade of exploring the cancer epigenome - biological and translational implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2013.776040

Phase I study of vorinostat in combination with temozolomide in patients with high-grade gliomas: North American Brain Tumor Consortium Study 04-03.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2013.776040

Inhibition of the proliferation of acquired aromatase inhibitor-resistant breast cancer cells by histone deacetylase inhibitor LBH589 (panobinostat).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2013.776040

A phase I trial of oral administration of panobinostat in combination with paclitaxel and carboplatin in patients with solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2013.776040

AML with 11q23/MLL abnormalities as defined by the WHO classification: incidence, partner chromosomes, FAB subtype, age distribution, and prognostic impact in an unselected series of 1897 cytogenetically analyzed AML cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2013.776040

10.1517/13543776.2013.776040

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23448241%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference