(Q58042312)

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3 February 2020

title

TAL1/SCL is downregulated upon histone deacetylase inhibition in T-cell acute lymphoblastic leukemia cells (English)

1 reference

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3 February 2020

1 reference

lymphoblastic leukemia

1 reference

T-cell acute lymphoblastic leukemia

inferred from title

1 reference

1

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3 February 2020

Sérgio F de Almeida

2

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3 February 2020

Maria do Carmo Fonseca

4

1 reference

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3 February 2020

João T. Barata

7

1 reference

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3 February 2020

author name string

A B A Laranjeira

3

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3 February 2020

J A Yunes

5

1 reference

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3 February 2020

P J Coffer

6

1 reference

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3 February 2020

publication date

7 June 2011

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3 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21647153%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

volume

25

1 reference

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3 February 2020

issue

10

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3 February 2020

page(s)

1578-1586

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https://scigraph.springernature.com/pub.10.1038/leu.2011.140

3 February 2020

exact match

0 references

cites work

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The DNA binding activity of TAL-1 is not required to induce leukemia/lymphoma in mice

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TAL1/SCL induces leukemia by inhibiting the transcriptional activity of E47/HEB.

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Formation of in vivo complexes between the TAL1 and E2A polypeptides of leukemic T cells

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Tal1/SCL binding to pericentromeric DNA represses transcription.

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021