(Q58090043)

PubMed ID

30382187

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30382187%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

title

δ-Secretase-cleaved Tau stimulates Aβ production via upregulating STAT1-BACE1 signaling in Alzheimer's disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6684859&resulttype=core&format=json

11 May 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6684859&resulttype=core&format=json

11 May 2020

Keqiang Ye

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6684859&resulttype=core&format=json

11 May 2020

author name string

Xiao-Guang Li

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6684859&resulttype=core&format=json

11 May 2020

Zhi-Hao Wang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6684859&resulttype=core&format=json

11 May 2020

Mingke Song

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6684859&resulttype=core&format=json

11 May 2020

Shan Ping Yu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6684859&resulttype=core&format=json

11 May 2020

Seong Su Kang

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6684859&resulttype=core&format=json

11 May 2020

Xia Liu

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6684859&resulttype=core&format=json

11 May 2020

Zhaohui Zhang

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6684859&resulttype=core&format=json

11 May 2020

Manling Xie

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6684859&resulttype=core&format=json

11 May 2020

Gong-Ping Liu

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6684859&resulttype=core&format=json

11 May 2020

Jian-Zhi Wang

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6684859&resulttype=core&format=json

11 May 2020

language of work or name

English

0 references

publication date

31 October 2018

1 reference

PubMed ID

30382187

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30382187%20AND%20SRC:MED&resulttype=core&format=json

1 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6684859&resulttype=core&format=json

describes a project that uses

11 May 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6684859/fullTextXML

inferred from PubMed Central ID database lookup

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Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer's disease

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Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease.

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7 January 2021

Cloning and expression of mouse legumain, a lysosomal endopeptidase

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Multistep autoactivation of asparaginyl endopeptidase in vitro and in vivo

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Neuroprotective actions of PIKE-L by inhibition of SET proteolytic degradation by asparagine endopeptidase

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The asparaginyl endopeptidase legumain after experimental stroke

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The amyloid hypothesis of Alzheimer's disease at 25 years

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APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy

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Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy

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7 January 2021

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

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7 January 2021

A specific amyloid-beta protein assembly in the brain impairs memory

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7 January 2021

Soluble amyloid beta-protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration

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7 January 2021

Neuropathology of nondemented aging: presumptive evidence for preclinical Alzheimer disease

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7 January 2021

Alzheimer disease pathology and longitudinal cognitive performance in the oldest-old with no dementia

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Imaging beta-amyloid burden in aging and dementia.

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7 January 2021

β-Amyloid burden in healthy aging: regional distribution and cognitive consequences.

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7 January 2021

The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics

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7 January 2021

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7 January 2021

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7 January 2021

Spatial and temporal relationships between plaques and tangles in Alzheimer-pathology.

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7 January 2021

Intraneuronal tau aggregation precedes diffuse plaque deposition, but amyloid-β changes occur before increases of tau in cerebrospinal fluid

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7 January 2021

Accelerated amyloid deposition, neurofibrillary degeneration and neuronal loss in double mutant APP/tau transgenic mice.

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7 January 2021

Human secreted tau increases amyloid-beta production

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7 January 2021

IFN-gamma-induced BACE1 expression is mediated by activation of JAK2 and ERK1/2 signaling pathways and direct binding of STAT1 to BACE1 promoter in astrocytes

1 reference

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7 January 2021

Constitutive JAK2/STAT1 activation regulates endogenous BACE1 expression in neurons

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7 January 2021

PKC ε activation prevents synaptic loss, Aβ elevation, and cognitive deficits in Alzheimer's disease transgenic mice

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7 January 2021

A novel defense mechanism that is activated on amyloid-beta insult to mediate cell survival: role of SGK1-STAT1/STAT2 signaling

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7 January 2021

Amyloid-β induces hepatic insulin resistance in vivo via JAK2.

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7 January 2021

Intra- and extracellular regulation of activity and processing of legumain by cystatin E/M.

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7 January 2021

Activation of asparaginyl endopeptidase leads to Tau hyperphosphorylation in Alzheimer disease

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7 January 2021

Transcriptional regulation of beta-secretase by p25/cdk5 leads to enhanced amyloidogenic processing

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7 January 2021

Beta-site APP cleaving enzyme up-regulation induced by 4-hydroxynonenal is mediated by stress-activated protein kinases pathways.

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7 January 2021

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7 January 2021

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7 January 2021

Inflammatory processes in Alzheimer's disease

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7 January 2021

Nonsteroidal anti-inflammatory drugs and peroxisome proliferator-activated receptor-gamma agonists modulate immunostimulated processing of amyloid precursor protein through regulation of beta-secretase.

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7 January 2021

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7 January 2021

Inhibition of JAK2 attenuates the increase in inflammatory markers in microglia from APP/PS1 mice

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7 January 2021

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7 January 2021

Lack of tau proteins rescues neuronal cell death and decreases amyloidogenic processing of APP in APP/PS1 mice.

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7 January 2021

Alzheimer neuropathologic alterations in aged cognitively normal subjects.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/30382187

12 December 2020

inferred from PubMed ID database lookup

Alzheimer's disease: the challenge of the second century

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/30382187

12 December 2020

inferred from PubMed ID database lookup

Inhibitory effect of 4-O-methylhonokiol on lipopolysaccharide-induced neuroinflammation, amyloidogenesis and memory impairment via inhibition of nuclear factor-kappaB in vitro and in vivo models

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/30382187

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/S41380-018-0286-Z

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6684859&resulttype=core&format=json

11 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6684859&resulttype=core&format=json

11 May 2020

1 reference