(Q59070890)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30250252%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

title

Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30250252%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

author name string

Yihe Huang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30250252%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

Weinan Sun

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30250252%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

Wei Lü

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30250252%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

Juan Du

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30250252%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

Paige A Winkler

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30250252%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

language of work or name

English

0 references

publication date

24 September 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30250252%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30250252%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

volume

562

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30250252%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

page(s)

145-149

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30250252%20AND%20SRC:MED&resulttype=core&format=json

24 April 2020

issue

7725

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30250252%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/s41586-018-0558-4

24 April 2020

exact match

0 references

cites work

The TRPM2 ion channel is required for sensitivity to warmth.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

The TRPM2 channel is a hypothalamic heat sensor that limits fever and can drive hypothermia

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Transient Receptor Potential Melastatin 2 (TRPM2) ion channel is required for innate immunity against Listeria monocytogenes

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Cooperative interaction of trp melastatin channel transient receptor potential (TRPM2) with its splice variant TRPM2 short variant is essential for endothelial cell apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Cyclic ADP-ribose and hydrogen peroxide synergize with ADP-ribose in the activation of TRPM2 channels

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Nicotinic acid adenine dinucleotide phosphate and cyclic ADP-ribose regulate TRPM2 channels in T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

TRPM2 activation by cyclic ADP-ribose at body temperature is involved in insulin secretion

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

TRPM2 functions as a lysosomal Ca2+-release channel in beta cells

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

TRPM2 channels protect against cardiac ischemia-reperfusion injury: role of mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Association of the putative susceptibility gene, transient receptor potential protein melastatin type 2, with bipolar disorder

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

The Transient Receptor Potential Melastatin 2 (TRPM2) Channel Contributes to β-Amyloid Oligomer-Related Neurotoxicity and Memory Impairment.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Accumulation of free ADP-ribose from mitochondria mediates oxidative stress-induced gating of TRPM2 cation channels

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Activation of the cation channel long transient receptor potential channel 2 (LTRPC2) by hydrogen peroxide. A splice variant reveals a mode of activation independent of ADP-ribose.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

ADP-Ribose Activates the TRPM2 Channel from the Sea Anemone Nematostella vectensis Independently of the NUDT9H Domain

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Sites of the NUDT9-H domain critical for ADP-ribose activation of the cation channel TRPM2.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Identification of the ADPR binding pocket in the NUDT9 homology domain of TRPM2.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Ligand-induced activation of human TRPM2 requires the terminal ribose of ADPR and involves Arg1433 and Tyr1349.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

The proposed channel-enzyme transient receptor potential melastatin 2 does not possess ADP ribose hydrolase activity

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Putative chanzyme activity of TRPM2 cation channel is unrelated to pore gating

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Three-dimensional reconstruction using transmission electron microscopy reveals a swollen, bell-shaped structure of transient receptor potential melastatin type 2 cation channel.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Conserved cysteine residues in the pore region are obligatory for human TRPM2 channel function

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Structure of a TRPM2 channel in complex with Ca2+ explains unique gating regulation.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Electron cryo-microscopy structure of a human TRPM4 channel

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Structure of the TRPV1 ion channel determined by electron cryo-microscopy

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Structures of the calcium-activated, non-selective cation channel TRPM4.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Structure of the cold- and menthol-sensing ion channel TRPM8.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Structure of the human TRPM4 ion channel in a lipid nanodisc

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Molecular and functional characterization of the melastatin-related cation channel TRPM3.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

LTRPC7 is a Mg.ATP-regulated divalent cation channel required for cell viability

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

TRPM6 forms the Mg2+ influx channel involved in intestinal and renal Mg2+ absorption

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Transient receptor potential melastatin 1 (TRPM1) is an ion-conducting plasma membrane channel inhibited by zinc ions

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Identification of pore residues engaged in determining divalent cationic permeation in transient receptor potential melastatin subtype channel 2.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Redox signal-mediated sensitization of transient receptor potential melastatin 2 (TRPM2) to temperature affects macrophage functions.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

The Integrity of the TRP Domain Is Pivotal for Correct TRPV1 Channel Gating

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Importance of a conserved sequence motif in transmembrane segment S3 for the gating of human TRPM8 and TRPM2

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Screening and large-scale expression of membrane proteins in mammalian cells for structural studies

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Fluorescence-detection size-exclusion chromatography for precrystallization screening of integral membrane proteins

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Automated electron microscope tomography using robust prediction of specimen movements

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Gctf: Real-time CTF determination and correction

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

RELION: implementation of a Bayesian approach to cryo-EM structure determination

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Frealign: An Exploratory Tool for Single-Particle Cryo-EM.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Guidelines for using Bsoft for high resolution reconstruction and validation of biomolecular structures from electron micrographs.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Features and development of Coot

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

The crystal structure and mutational analysis of human NUDT9

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Molecular dynamics flexible fitting: a practical guide to combine cryo-electron microscopy and X-ray crystallography

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Towards automated crystallographic structure refinement with phenix.refine

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

MolProbity: all-atom structure validation for macromolecular crystallography

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

EMRinger: side chain-directed model and map validation for 3D cryo-electron microscopy.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

UCSF Chimera--a visualization system for exploratory research and analysis

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

cisTEM, user-friendly software for single-particle image processing.

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021

JPred4: a protein secondary structure prediction server

1 reference

https://api.crossref.org/works/10.1038%2FS41586-018-0558-4

7 January 2021