(Q60301650)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30582059%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

title

Pancreatic cancer chemo-resistance is driven by tumor phenotype rather than tumor genotype (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30582059%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

1 reference

1 reference

3

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15 April 2020

author name string

Mirna Swayden

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30582059%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

Juan Iovanna

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30582059%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

language of work or name

English

0 references

publication date

17 December 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30582059%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30582059%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

volume

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30582059%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30582059%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

page(s)

e01055

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30582059%20AND%20SRC:MED&resulttype=core&format=json

Role of transforming growth factor-beta in repair and fibrosis

15 April 2020

cites work

1 reference

12 December 2020

Dpc-4 protein is expressed in virtually all human intraductal papillary mucinous neoplasms of the pancreas: comparison with conventional ductal adenocarcinomas

1 reference

12 December 2020

Inhibition of phosphatidylinositide 3-kinase enhances gemcitabine-induced apoptosis in human pancreatic cancer cells.

1 reference

12 December 2020

Hypoxia-inducible factor-1-dependent regulation of the multidrug resistance (MDR1) gene.

1 reference

12 December 2020

Nuclear factor-kappa B and cancer: its role in prevention and therapy

1 reference

12 December 2020

Tumor-stroma interaction of human pancreatic cancer: acquired resistance to anticancer drugs and proliferation regulation is dependent on extracellular matrix proteins.

1 reference

12 December 2020

Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis

1 reference

12 December 2020

Mitogen-activated protein kinases and chemoresistance in pancreatic cancer cells

1 reference

12 December 2020

Chemotherapy: induction of stress responses

1 reference

12 December 2020

Reactive oxygen species: a breath of life or death?

1 reference

12 December 2020

HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity

1 reference

12 December 2020

Molecular genetics of pancreatic intraepithelial neoplasia

1 reference

12 December 2020

Hypoxia and metabolism. Hypoxia, DNA repair and genetic instability.

1 reference

12 December 2020

Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer

1 reference

12 December 2020

Pancreatic carcinogenesis

1 reference

12 December 2020

Pancreatic intraepithelial neoplasia revisited and updated

1 reference

12 December 2020

Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway

1 reference

12 December 2020

MicroRNA-21 modulates biological functions of pancreatic cancer cells including their proliferation, invasion, and chemoresistance

1 reference

12 December 2020

Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

1 reference

12 December 2020

RETRACTED: 3,3'-Diindolylmethane enhances chemosensitivity of multiple chemotherapeutic agents in pancreatic cancer

1 reference

12 December 2020

Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer

1 reference

12 December 2020

Masitinib combined with standard gemcitabine chemotherapy: in vitro and in vivo studies in human pancreatic tumour cell lines and ectopic mouse model

1 reference

12 December 2020

Preoperative/neoadjuvant therapy in pancreatic cancer: a systematic review and meta-analysis of response and resection percentages

1 reference

12 December 2020

Precursor lesions of pancreatic cancer

1 reference

12 December 2020

Pancreatic Cancer Cells Resistant to Chemoradiotherapy Rich in “Stem-Cell-Like” Tumor Cells

1 reference

12 December 2020

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

1 reference

12 December 2020

Methylation-mediated silencing of TMS1 in pancreatic cancer and its potential contribution to chemosensitivity.

1 reference

12 December 2020

Hallmarks of Cancer: The Next Generation

1 reference

12 December 2020

Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy

1 reference

12 December 2020

Pancreatic stellate cells radioprotect pancreatic cancer cells through β1-integrin signaling.

1 reference

12 December 2020

FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer

1 reference

12 December 2020

Notch signaling activated by replication stress-induced expression of midkine drives epithelial-mesenchymal transition and chemoresistance in pancreatic cancer

1 reference

12 December 2020

The underlying mechanism for the PARP and BRCA synthetic lethality: clearing up the misunderstandings

1 reference

12 December 2020

Conventional chemotherapy of advanced pancreatic cancer

1 reference

12 December 2020

WNT5A-NFAT signaling mediates resistance to apoptosis in pancreatic cancer

1 reference

12 December 2020

miRNA-181b increases the sensitivity of pancreatic ductal adenocarcinoma cells to gemcitabine in vitro and in nude mice by targeting BCL-2.

1 reference

12 December 2020

A starring role for stellate cells in the pancreatic cancer microenvironment

1 reference

12 December 2020

Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine

1 reference

12 December 2020

Therapeutic targeting of hyaluronan in the tumor stroma

1 reference

12 December 2020

ZEB1 in Pancreatic Cancer.

1 reference

12 December 2020

Macrophages increase the resistance of pancreatic adenocarcinoma cells to gemcitabine by upregulating cytidine deaminase

1 reference

12 December 2020

Intratumoral functional heterogeneity and chemotherapy

1 reference

12 December 2020

Identification of new mechanisms of cellular response to chemotherapy by tracking changes in post-translational modifications by ubiquitin and ubiquitin-like proteins

1 reference

12 December 2020

Hypoxia in tumors: pathogenesis-related classification, characterization of hypoxia subtypes, and associated biological and clinical implications

1 reference

12 December 2020

The role of inflammation in pancreatic cancer

1 reference

12 December 2020

miR-211 modulates gemcitabine activity through downregulation of ribonucleotide reductase and inhibits the invasive behavior of pancreatic cancer cells

1 reference

12 December 2020

MiR-497 downregulation contributes to the malignancy of pancreatic cancer and associates with a poor prognosis

1 reference

12 December 2020

Mutant p53 stimulates chemoresistance of pancreatic adenocarcinoma cells to gemcitabine

1 reference

12 December 2020

Desmoplasia and chemoresistance in pancreatic cancer

1 reference

12 December 2020

Desmoplasia in Primary Tumors and Metastatic Lesions of Pancreatic Cancer

1 reference

12 December 2020

Whole genomes redefine the mutational landscape of pancreatic cancer

1 reference

12 December 2020

Transcriptomic analysis predicts survival and sensitivity to anticancer drugs of patients with a pancreatic adenocarcinoma

1 reference

12 December 2020

The long non-coding RNA HOTTIP promotes progression and gemcitabine resistance by regulating HOXA13 in pancreatic cancer

1 reference

12 December 2020

MicroRNA-33a-mediated downregulation of Pim-3 kinase expression renders human pancreatic cancer cells sensitivity to gemcitabine.

1 reference

12 December 2020

The role of pancreatic stellate cells in pancreatic cancer

1 reference

12 December 2020

Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma.

1 reference

12 December 2020

A Revised Classification System and Recommendations From the Baltimore Consensus Meeting for Neoplastic Precursor Lesions in the Pancreas

1 reference

12 December 2020

Cancer statistics, 2016

1 reference

12 December 2020

Phase Ib Study of PEGylated Recombinant Human Hyaluronidase and Gemcitabine in Patients with Advanced Pancreatic Cancer.

1 reference

12 December 2020

Genomic analyses identify molecular subtypes of pancreatic cancer

1 reference

12 December 2020

The Landscape of Pancreatic Cancer Therapeutic Resistance Mechanisms

1 reference

12 December 2020

Downregulated miR-506 expression facilitates pancreatic cancer progression and chemoresistance via SPHK1/Akt/NF-κB signaling.

1 reference

12 December 2020

P300 inhibition enhances gemcitabine-induced apoptosis of pancreatic cancer

1 reference

12 December 2020

A pancreatic ductal adenocarcinoma subpopulation is sensitive to FK866, an inhibitor of NAMPT.

1 reference

12 December 2020

Integrated Patient-Derived Models Delineate Individualized Therapeutic Vulnerabilities of Pancreatic Cancer

1 reference

12 December 2020

Cancer-associated fibroblast exosomes regulate survival and proliferation of pancreatic cancer cells.

1 reference

12 December 2020

Periostin promotes the chemotherapy resistance to gemcitabine in pancreatic cancer.

1 reference

12 December 2020

Linc-ROR confers gemcitabine resistance to pancreatic cancer cells via inducing autophagy and modulating the miR-124/PTBP1/PKM2 axis

1 reference

12 December 2020

Definition and identification of small RNA sponges: Focus on miRNA sequestration

1 reference

12 December 2020

Exosomes confer chemoresistance to pancreatic cancer cells by promoting ROS detoxification and miR-155-mediated suppression of key gemcitabine-metabolising enzyme, DCK.

1 reference

12 December 2020

Gene expression profiling of patient-derived pancreatic cancer xenografts predicts sensitivity to the BET bromodomain inhibitor JQ1: implications for individualized medicine efforts

1 reference

12 December 2020

Drug resistance in pancreatic cancer: Impact of altered energy metabolism

1 reference

12 December 2020

Pancreatic cancer heterogeneity and response to Mek inhibition.

1 reference

12 December 2020

Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine

1 reference

12 December 2020

Pancreatic Adenocarcinoma Therapeutic Targets Revealed by Tumor-Stroma Cross-Talk Analyses in Patient-Derived Xenografts.

1 reference

12 December 2020

Phase II trial of veliparib in patients with previously treated BRCA-mutated pancreas ductal adenocarcinoma.

1 reference

12 December 2020

Phase 1 trial evaluating cisplatin, gemcitabine, and veliparib in 2 patient cohorts: Germline BRCA mutation carriers and wild-type BRCA pancreatic ductal adenocarcinoma.

1 reference

12 December 2020

Promising molecular mechanisms responsible for gemcitabine resistance in cancer

1 reference

12 December 2020

10.1016/J.HELIYON.2018.E01055

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30582059%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30582059%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

PubMed publication ID

30582059

1 reference