(Q61570960)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30127528%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

title

Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry (English)

1 reference

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19 April 2020

1 reference

1

1 reference

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19 April 2020

Mark W Zimmerman

2

1 reference

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19 April 2020

Neekesh Dharia

3

1 reference

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19 April 2020

Brian J. Abraham

4

1 reference

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19 April 2020

Francisca Vazquez

10

1 reference

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19 April 2020

Aviad Tsherniak

11

1 reference

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19 April 2020

William C Hahn

12

1 reference

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19 April 2020

Todd Golub

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30127528%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

Richard A. Young

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30127528%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

Kimberly Stegmaier

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30127528%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

9

David E Root

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30127528%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

author name string

Amanda Balboni Iniguez

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30127528%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

Nina Weichert-Leahey

6

1 reference

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19 April 2020

Shuning He

7

1 reference

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19 April 2020

John M Krill-Burger

8

1 reference

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19 April 2020

A Thomas Look

15

1 reference

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19 April 2020

language of work or name

English

0 references

publication date

20 August 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30127528%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30127528%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

volume

50

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30127528%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

issue

9

1 reference

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19 April 2020

page(s)

1240-1246

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https://scigraph.springernature.com/pub.10.1038/s41588-018-0191-z

19 April 2020

exact match

0 references

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

Genome-scale CRISPR-Cas9 knockout screening in human cells

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

Genetic screens in human cells using the CRISPR-Cas9 system

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

CRISPR knockout screening outperforms shRNA and CRISPRi in identifying essential genes.

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

Systematic comparison of CRISPR/Cas9 and RNAi screens for essential genes

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

MYC Drives a Subset of High-Risk Pediatric Neuroblastomas and Is Activated through Mechanisms Including Enhancer Hijacking and Focal Enhancer Amplification

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

Gene ontology: tool for the unification of biology

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

Gene Ontology Consortium: going forward

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

Pre-clinical evaluation of the MDM2-p53 antagonist RG7388 alone and in combination with chemotherapy in neuroblastoma

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

Dual CDK4/CDK6 inhibition induces cell-cycle arrest and senescence in neuroblastoma

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

BRG1/SMARCA4 is essential for neuroblastoma cell viability through modulation of cell death and survival pathways

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

Insulin receptor substrate (IRS)-2, not IRS-1, protects human neuroblastoma cells against apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

WIP1 phosphatase as a potential therapeutic target in neuroblastoma

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

Signals and switches in Mammalian neural crest cell differentiation

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

Germline PHOX2B mutation in hereditary neuroblastoma

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

Cyclin D1 is a direct transcriptional target of GATA3 in neuroblastoma tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

Early detection of tumor relapse/regrowth by consecutive minimal residual disease monitoring in high-risk neuroblastoma patients

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

STRING v10: protein-protein interaction networks, integrated over the tree of life

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

Core transcriptional regulatory circuit controlled by the TAL1 complex in human T cell acute lymphoblastic leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

Oncogene regulation. An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

Models of human core transcriptional regulatory circuitries

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

Core transcriptional regulatory circuitry in human embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

Master transcription factors and mediator establish super-enhancers at key cell identity genes

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

Super-enhancers in the control of cell identity and disease

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

Heterogeneity of neuroblastoma cell identity defined by transcriptional circuitries.

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

Neuroblastoma is composed of two super-enhancer-associated differentiation states.

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

Pioneer factors govern super-enhancer dynamics in stem cell plasticity and lineage choice

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

1 reference

7 January 2021

Transcriptional amplification in tumor cells with elevated c-Myc.

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

Enhancer invasion shapes MYCN-dependent transcriptional amplification in neuroblastoma.

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

CDK7 inhibition suppresses super-enhancer-linked oncogenic transcription in MYCN-driven cancer.

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

Targeting MYCN in neuroblastoma by BET bromodomain inhibition

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

Isobolographic analysis of interactions: an update on applications and utility

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

Drug combination studies and their synergy quantification using the Chou-Talalay method

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

Criteria for analyzing interactions between biologically active agents

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

Targeting transcription regulation in cancer with a covalent CDK7 inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism.

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

1 reference

https://api.crossref.org/works/10.1038%2FS41588-018-0191-Z

7 January 2021

10.1038/S41588-018-0191-Z

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30127528%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30127528%20AND%20SRC:MED&resulttype=core&format=json

19 April 2020

1 reference