(Q62835353)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25778466%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

title

A novel UGT1 marker associated with better tolerance against irinotecan-induced severe neutropenia in metastatic colorectal cancer patients (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25778466%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

metastatic colon cancer

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1 reference

1

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3 March 2020

Erika Cecchin

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25778466%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Giuseppe Toffoli

11

1 reference

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3 March 2020

Chantal Guillemette

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25778466%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

9

M H Court

1 reference

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3 March 2020

author name string

I Laverdiere

2

1 reference

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3 March 2020

A Tourancheau

3

1 reference

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3 March 2020

D Jonker

4

1 reference

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3 March 2020

F Couture

5

1 reference

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3 March 2020

L Villeneuve

7

1 reference

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3 March 2020

M Harvey

8

1 reference

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3 March 2020

F Innocenti

10

1 reference

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3 March 2020

E Lévesque

12

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3 March 2020

language of work or name

English

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publication date

17 March 2015

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25778466%20AND%20SRC:MED&resulttype=core&format=json

The Pharmacogenomics Journal

3 March 2020

published in

1 reference

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3 March 2020

volume

15

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3 March 2020

issue

6

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3 March 2020

page(s)

513-520

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25778466%20AND%20SRC:MED&resulttype=core&format=json

HBS1L-MYB intergenic variants modulate fetal hemoglobin via long-range MYB enhancers

3 March 2020

cites work

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12 December 2020

Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: a balanced polymorphism for regulation of bilirubin metabolism?

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12 December 2020

Refining the UGT1A haplotype associated with irinotecan-induced hematological toxicity in metastatic colorectal cancer patients treated with 5-fluorouracil/irinotecan-based regimens.

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12 December 2020

Dose-finding and pharmacokinetic study to optimize the dosing of irinotecan according to the UGT1A1 genotype of patients with cancer

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12 December 2020

The effect of UGT1A and UGT2B polymorphisms on colorectal cancer risk: haplotype associations and gene–environment interactions

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12 December 2020

A comparison of bayesian methods for haplotype reconstruction from population genotype data

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12 December 2020

PharmGKB summary: very important pharmacogene information for UGT1A1

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12 December 2020

Dose-dependent association between UGT1A1*28 polymorphism and irinotecan-induced diarrhoea: a meta-analysis

1 reference

12 December 2020

THE NOVEL UGT1A9 INTRONIC I399 POLYMORPHISM APPEARS AS A PREDICTOR OF 7-ETHYL-10-HYDROXYCAMPTOTHECIN GLUCURONIDATION LEVELS IN THE LIVER

1 reference

12 December 2020

Haplotypes of variants in the UDP-glucuronosyltransferase1A9 and 1A1 genes.

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12 December 2020

Genome-wide association meta-analysis for total serum bilirubin levels

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12 December 2020

The Impact of UGT1A8, UGT1A9, and UGT2B7 Genetic Polymorphisms on the Pharmacokinetic Profile of Mycophenolic Acid After a Single Oral Dose in Healthy Volunteers

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12 December 2020

UGT1A1 polymorphisms are important determinants of dietary carcinogen detoxification in the liver

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12 December 2020

Predictive role of the UGT1A1, UGT1A7, and UGT1A9 genetic variants and their haplotypes on the outcome of metastatic colorectal cancer patients treated with fluorouracil, leucovorin, and irinotecan.

1 reference

12 December 2020

Intergenic polymorphisms in the amphiregulin gene region as biomarkers in metastatic colorectal cancer patients treated with anti-EGFR plus irinotecan.

1 reference

12 December 2020

Pharmacogenomics of Human Uridine Diphospho-Glucuronosyltransferases and Clinical Implications

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12 December 2020

Pharmacogenetics of irinotecan metabolism and transport: an update

1 reference

12 December 2020

Dose-dependent association between UGT1A1*28 genotype and irinotecan-induced neutropenia: low doses also increase risk

1 reference

12 December 2020

A genotype-directed phase I-IV dose-finding study of irinotecan in combination with fluorouracil/leucovorin as first-line treatment in advanced colorectal cancer

1 reference

12 December 2020

Hepatic transport, metabolism and biliary excretion of irinotecan in a cancer patient with an external bile drain

1 reference

12 December 2020

Common human UGT1A polymorphisms and the altered metabolism of irinotecan active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38).

1 reference

12 December 2020

Irinotecan pharmacogenomics

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12 December 2020

Pharmacogenetics of ABC and SLC transporters in metastatic colorectal cancer patients receiving first-line FOLFIRI treatment.

1 reference

12 December 2020

Allele-specific transcriptional activity at type 2 diabetes-associated single nucleotide polymorphisms in regions of pancreatic islet open chromatin at the JAZF1 locus

1 reference

12 December 2020

PLINK: a tool set for whole-genome association and population-based linkage analyses

1 reference

12 December 2020

The Role of UGT1A1*28 Polymorphism in the Pharmacodynamics and Pharmacokinetics of Irinotecan in Patients With Metastatic Colorectal Cancer

1 reference

12 December 2020

The UDP-glucuronosyltransferase (UGT) 1A polymorphism c.2042C>G (rs8330) is associated with increased human liver acetaminophen glucuronidation, increased UGT1A exon 5a/5b splice variant mRNA ratio, and decreased risk of unintentional acetaminophen-

1 reference

12 December 2020

A New Statistical Method for Haplotype Reconstruction from Population Data

1 reference

12 December 2020

Impact of the UGT1A1*28 allele on response to irinotecan: a systematic review and meta-analysis

1 reference

12 December 2020

Genotype-driven phase I study of irinotecan administered in combination with fluorouracil/leucovorin in patients with metastatic colorectal cancer

1 reference

12 December 2020

Identifiers

DOI

10.1038/TPJ.2015.12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25778466%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

3 March 2020

0 references

1 reference

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3 March 2020

PubMed publication ID

25778466

1 reference