(Q63976958)

6

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Richard Burchmore

object named as

Richard Burchmore

5

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author name string

Matthew J Keuss

1

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Roland Hjerpe

2

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Oliver Hsia

3

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Robert Gourlay

describes a project that uses

4

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language of work or name

English

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publication date

15 March 2019

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published in

The EMBO Journal

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volume

38

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issue

6

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page(s)

e100024

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ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6418418/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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12 December 2020

Role of poly(ADP-ribose) formation in DNA repair

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12 December 2020

A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein

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Poly(ADP-ribose) in the cellular response to DNA damage

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Poly ADP-ribose glycohydrolase from rat liver nuclei, a novel enzyme degrading the polymer

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Purification and Properties of a Glycohydrolase from Calf Thymus Splitting Ribose-Ribose Linkages of Poly(Adenosine Diphosphate Ribose)

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(ADP-ribose)n participates in DNA excision repair

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12 December 2020

Activation of the heat-stable polypeptide of the ATP-dependent proteolytic system

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Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdown

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Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade

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12 December 2020

In vivo disassembly of free polyubiquitin chains by yeast Ubp14 modulates rates of protein degradation by the proteasome

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12 December 2020

Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia.

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12 December 2020

Poly(ADP-ribose) polymerase gene disruption conferred mice resistant to streptozotocin-induced diabetes

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12 December 2020

Poly(ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes

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12 December 2020

Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin.

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12 December 2020

Resistance to endotoxic shock as a consequence of defective NF-kappaB activation in poly (ADP-ribose) polymerase-1 deficient mice

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12 December 2020

Prevention of endotoxin-induced lethality, but not of liver apoptosis in poly(ADP-ribose) polymerase-deficient mice

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12 December 2020

Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion

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12 December 2020

Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalpha

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12 December 2020

Modification of cullin-1 by ubiquitin-like protein Nedd8 enhances the activity of SCF(skp2) toward p27(kip1).

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12 December 2020

Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages

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12 December 2020

An intact NEDD8 pathway is required for Cullin-dependent ubiquitylation in mammalian cells

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12 December 2020

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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12 December 2020

Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor

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12 December 2020

Poly(ADP-ribose) polymerase-1 (PARP-1) is required in murine cell lines for base excision repair of oxidative DNA damage in the absence of DNA polymerase beta

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12 December 2020

NEDP1, a highly conserved cysteine protease that deNEDDylates Cullins

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12 December 2020

Identification and characterization of DEN1, a deneddylase of the ULP family

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12 December 2020

DEN1 is a dual function protease capable of processing the C terminus of Nedd8 and deconjugating hyper-neddylated CUL1

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12 December 2020

A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage

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12 December 2020

Transcription regulation of TNF-alpha-early response genes by poly(ADP-ribose) polymerase-1 in murine heart endothelial cells

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12 December 2020

Alkylating DNA damage stimulates a regulated form of necrotic cell death

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12 December 2020

The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase

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12 December 2020

Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex

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12 December 2020

Apoptosis-inducing factor substitutes for caspase executioners in NMDA-triggered excitotoxic neuronal death.

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12 December 2020

Function and regulation of cullin-RING ubiquitin ligases

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12 December 2020

Structural basis of NEDD8 ubiquitin discrimination by the deNEDDylating enzyme NEDP1.

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12 December 2020

The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae

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12 December 2020

Absolute quantification of proteins by LCMSE: a virtue of parallel MS acquisition

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12 December 2020

Mdm2-mediated NEDD8 modification of TAp73 regulates its transactivation function

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12 December 2020

Poly(ADP-ribose) (PAR) polymer is a death signal

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12 December 2020

Pulse inhibition of histone deacetylases induces complete resistance to oxidative death in cortical neurons without toxicity and reveals a role for cytoplasmic p21(waf1/cip1) in cell cycle-independent neuroprotection

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12 December 2020

TNF-alpha induces two distinct caspase-8 activation pathways

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12 December 2020

Histone deacetylase inhibitors and genomic instability

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12 December 2020

DEN1 deneddylates non-cullin proteins in vivo.

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12 December 2020

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

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12 December 2020

ProMoST: a tool for calculating the pI and molecular mass of phosphorylated and modified proteins on two-dimensional gels

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12 December 2020

The mechanism of poly-NEDD8 chain formation in vitro

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12 December 2020

Parthanatos, a messenger of death

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12 December 2020

An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

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12 December 2020

Molecular mechanism of poly(ADP-ribosyl)ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites

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12 December 2020

Substrate-assisted inhibition of ubiquitin-like protein-activating enzymes: the NEDD8 E1 inhibitor MLN4924 forms a NEDD8-AMP mimetic in situ

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12 December 2020

NAD+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal death

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12 December 2020

PARP inhibition: PARP1 and beyond

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12 December 2020

Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity

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12 December 2020

Systematic in vivo RNAi analysis identifies IAPs as NEDD8-E3 ligases

1 reference

12 December 2020

Crystal Structures of Poly(ADP-ribose) Polymerase-1 (PARP-1) Zinc Fingers Bound to DNA: STRUCTURAL AND FUNCTIONAL INSIGHTS INTO DNA-DEPENDENT PARP-1 ACTIVITY

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12 December 2020

Andromeda: a peptide search engine integrated into the MaxQuant environment

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12 December 2020

Poly(ADP-ribose) (PAR) binding to apoptosis-inducing factor is critical for PAR polymerase-1-dependent cell death (parthanatos)

1 reference

12 December 2020

Purification of human PARP-1 and PARP-1 domains from Escherichia coli for structural and biochemical analysis.

1 reference

12 December 2020

Systematic and quantitative assessment of the ubiquitin-modified proteome

1 reference

12 December 2020

Changes in the ratio of free NEDD8 to ubiquitin triggers NEDDylation by ubiquitin enzymes

1 reference

12 December 2020

Enhanced killing of cancer cells by poly(ADP-ribose) polymerase inhibitors and topoisomerase I inhibitors reflects poisoning of both enzymes.

1 reference

12 December 2020

The ubiquitin E1 enzyme Ube1 mediates NEDD8 activation under diverse stress conditions

1 reference

12 December 2020

Ubiquitin-like proteins

1 reference

12 December 2020

Structural Basis for DNA Damage-Dependent Poly(ADP-ribosyl)ation by Human PARP-1

1 reference

12 December 2020

NEDD8 Overexpression Results in Neddylation of Ubiquitin Substrates by the Ubiquitin Pathway

1 reference

12 December 2020

Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors

1 reference

12 December 2020

Multiplex genome engineering using CRISPR/Cas systems

1 reference

12 December 2020

RNA-guided human genome engineering via Cas9

1 reference

12 December 2020

Cand1 promotes assembly of new SCF complexes through dynamic exchange of F box proteins

1 reference

12 December 2020

CSN- and CAND1-dependent remodelling of the budding yeast SCF complex.

1 reference

12 December 2020

CAND1 controls in vivo dynamics of the cullin 1-RING ubiquitin ligase repertoire

1 reference

12 December 2020

TRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin-RING ligase complexes

1 reference

12 December 2020

Phosphoproteomic approach to characterize protein mono- and poly(ADP-ribosyl)ation sites from cells.

1 reference

12 December 2020

Improved genome editing in human cell lines using the CRISPR method

1 reference

12 December 2020

Protein neddylation: beyond cullin-RING ligases

1 reference

12 December 2020

Neddylation inhibition impairs spine development, destabilizes synapses and deteriorates cognition.

1 reference

12 December 2020

The promise and perils of HDAC inhibitors in neurodegeneration

1 reference

12 December 2020

DENEDDYLASE1 deconjugates NEDD8 from non-cullin protein substrates in Arabidopsis thaliana

1 reference

12 December 2020

Structural Basis of Detection and Signaling of DNA Single-Strand Breaks by Human PARP-1.

1 reference

12 December 2020

Characterization of the mammalian family of DCN-type NEDD8 E3 ligases

1 reference

12 December 2020

Cultured networks of excitatory projection neurons and inhibitory interneurons for studying human cortical neurotoxicity

1 reference

12 December 2020

The increasing complexity of the ubiquitin code

1 reference

12 December 2020

Serine is a new target residue for endogenous ADP-ribosylation on histones.

1 reference

12 December 2020

A nuclease that mediates cell death induced by DNA damage and poly(ADP-ribose) polymerase-1

1 reference

12 December 2020

DENEDDYLASE1 Protein Counters Automodification of Neddylating Enzymes to Maintain NEDD8 Protein Homeostasis in Arabidopsis.

1 reference

12 December 2020

ADPriboDB: The database of ADP-ribosylated proteins

1 reference

12 December 2020

SENP8 limits aberrant neddylation of NEDD8 pathway components to promote cullin-RING ubiquitin ligase function

1 reference

12 December 2020