(Q64057672)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31078136%20AND%20SRC:MED&resulttype=core&format=json

25 April 2020

1 reference

17 July 2021

Implications of altered NAD metabolism in metabolic disorders (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31078136%20AND%20SRC:MED&resulttype=core&format=json

25 April 2020

1 reference

17 July 2021

1 reference

17 July 2021

4

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25 April 2020

author name string

Keisuke Okabe

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31078136%20AND%20SRC:MED&resulttype=core&format=json

25 April 2020

Keisuke Yaku

series ordinal

2

1 reference

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25 April 2020

Kazuyuki Tobe

series ordinal

3

1 reference

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25 April 2020

language of work or name

English

0 references

publication date

11 May 2019

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31078136%20AND%20SRC:MED&resulttype=core&format=json

25 April 2020

17 July 2021

Journal of Biomedical Science

2 references

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25 April 2020

17 July 2021

26

1 reference

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25 April 2020

issue

1

1 reference

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25 April 2020

page(s)

34

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Creative Commons Attribution 4.0 International

25 April 2020

copyright license

1 reference

The use of nicotinamide to modify the toxicity of streptozotocin diabetes without loss of antitumor activity.

17 July 2021

cites work

1 reference

12 December 2020

Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor

1 reference

12 December 2020

Ultrastructural localization of CD38 immunoreactivity in rat brain.

1 reference

12 December 2020

A role of nicotinamide-induced increase in pancreatic beta-cell mass on blood glucose control after discontinuation of the treatment in partially pancreatectomized OLETF rats.

1 reference

12 December 2020

Ligand-induced internalization of CD38 results in intracellular Ca2+ mobilization: role of NAD+ transport across cell membranes

1 reference

12 December 2020

CD38-dependent ADP-ribosyl cyclase activity in developing and adult mouse brain

1 reference

12 December 2020

PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect

1 reference

12 December 2020

Influence of nicotinic acid on serum cholesterol in man.

1 reference

12 December 2020

The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells

1 reference

12 December 2020

RETRACTED: Visfatin: a protein secreted by visceral fat that mimics the effects of insulin

1 reference

12 December 2020

Interleukin-6 is a negative regulator of visfatin gene expression in 3T3-L1 adipocytes

1 reference

12 December 2020

Niacin mediates lipolysis in adipose tissue through its G-protein coupled receptor HM74A

1 reference

12 December 2020

Increased dosage of mammalian Sir2 in pancreatic beta cells enhances glucose-stimulated insulin secretion in mice

1 reference

12 December 2020

Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms

1 reference

12 December 2020

Nicotinamide protected first-phase insulin response (FPIR) and prevented clinical disease in first-degree relatives of type-1 diabetics

1 reference

12 December 2020

Elevated plasma level of visfatin/pre-B cell colony-enhancing factor in patients with type 2 diabetes mellitus

1 reference

12 December 2020

Effect of standard nicotinamide in the prevention of type 1 diabetes in first degree relatives of persons with type 1 diabetes.

1 reference

12 December 2020

Nampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme

1 reference

12 December 2020

NAD+ and vitamin B3: from metabolism to therapies

1 reference

12 December 2020

Sirt1 protects against high-fat diet-induced metabolic damage

1 reference

12 December 2020

Evolution and function of the ADP ribosyl cyclase/CD38 gene family in physiology and pathology

1 reference

12 December 2020

Nicotinamide phosphoribosyltransferase (NAMPT/PBEF/visfatin) is constitutively released from human hepatocytes

1 reference

12 December 2020

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

1 reference

12 December 2020

Lack of SIRT1 (Mammalian Sirtuin 1) activity leads to liver steatosis in the SIRT1+/- mice: a role of lipid mobilization and inflammation

1 reference

12 December 2020

Intracellular nicotinamide phosphoribosyltransferase protects against hepatocyte apoptosis and is down-regulated in nonalcoholic fatty liver disease

1 reference

12 December 2020

An evaluation of visfatin levels in obese subjects.

1 reference

12 December 2020

Modulation of HDL metabolism by the niacin receptor GPR109A in mouse hepatocytes

1 reference

12 December 2020

Visceral adipose tissue visfatin in nonalcoholic fatty liver disease

1 reference

12 December 2020

Expression of neuropeptide Y, omentin and visfatin in visceral and subcutaneous adipose tissues in humans: relation to endocrine and clinical parameters.

1 reference

12 December 2020

Fatty liver is associated with reduced SIRT3 activity and mitochondrial protein hyperacetylation

1 reference

12 December 2020

Phosphate-responsive signaling pathway is a novel component of NAD+ metabolism in Saccharomyces cerevisiae

1 reference

12 December 2020

Pathways and subcellular compartmentation of NAD biosynthesis in human cells: from entry of extracellular precursors to mitochondrial NAD generation.

1 reference

12 December 2020

Nicotinamide phosphoribosyltransferase/visfatin does not catalyze nicotinamide mononucleotide formation in blood plasma

1 reference

12 December 2020

Nicotinamide mononucleotide protects against pro-inflammatory cytokine-mediated impairment of mouse islet function

1 reference

12 December 2020

Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice

1 reference

12 December 2020

Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy

1 reference

12 December 2020

Increased levels and adipose tissue expression of visfatin in morbidly obese women: the relationship with pro-inflammatory cytokines

1 reference

12 December 2020

Increased hepatic synthesis and dysregulation of cholesterol metabolism is associated with the severity of nonalcoholic fatty liver disease

1 reference

12 December 2020

The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity

1 reference

12 December 2020

Niacin lipid efficacy is independent of both the niacin receptor GPR109A and free fatty acid suppression

1 reference

12 December 2020

Establishment of true niacin deficiency in quinolinic acid phosphoribosyltransferase knockout mice

1 reference

12 December 2020

Plasma visfatin levels and gene expression in morbidly obese women with associated fatty liver disease

1 reference

12 December 2020

The adipocytokine Nampt and its product NMN have no effect on beta-cell survival but potentiate glucose stimulated insulin secretion

1 reference

12 December 2020

Expression and regulation of nampt in human islets

1 reference

12 December 2020

CD38 and CD157: a long journey from activation markers to multifunctional molecules

1 reference

12 December 2020

Elevated microRNA-34a in obesity reduces NAD+ levels and SIRT1 activity by directly targeting NAMPT.

1 reference

12 December 2020

The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

1 reference

12 December 2020

Association of adipokines with obesity in children and adolescents

1 reference

12 December 2020

Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide

1 reference

12 December 2020

Hepatic SIRT1 attenuates hepatic steatosis and controls energy balance in mice by inducing fibroblast growth factor 21.

1 reference

12 December 2020

Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging

1 reference

12 December 2020

Hypothalamic SIRT1 prevents age-associated weight gain by improving leptin sensitivity in mice.

1 reference

12 December 2020

AMPK at the nexus of energetics and aging.

1 reference

12 December 2020

Deficiency of nicotinamide mononucleotide adenylyltransferase 3 (nmnat3) causes hemolytic anemia by altering the glycolytic flow in mature erythrocytes.

1 reference

12 December 2020

Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases

1 reference

12 December 2020

Effects of extended-release niacin with laropiprant in high-risk patients

1 reference

12 December 2020

P7C3 neuroprotective chemicals function by activating the rate-limiting enzyme in NAD salvage

1 reference

12 December 2020

Metabolic syndrome: a closer look at the growing epidemic and its associated pathologies

1 reference

12 December 2020

Increasing NAD synthesis in muscle via nicotinamide phosphoribosyltransferase is not sufficient to promote oxidative metabolism

1 reference

12 December 2020

Nutrient-sensing mechanisms across evolution

1 reference

12 December 2020

SIRT1-Mediated eNAMPT Secretion from Adipose Tissue Regulates Hypothalamic NAD+ and Function in Mice

1 reference

12 December 2020

Niacin as antidyslipidemic drug

1 reference

12 December 2020

Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice

1 reference

12 December 2020

Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver

1 reference

12 December 2020

Nicotinamide Riboside Is a Major NAD+ Precursor Vitamin in Cow Milk.

1 reference

12 December 2020

NAD⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice

1 reference

12 December 2020

Hepatic NAD(+) deficiency as a therapeutic target for non-alcoholic fatty liver disease in ageing.

1 reference

12 December 2020

Nicotinamide Riboside Opposes Type 2 Diabetes and Neuropathy in Mice

1 reference

12 December 2020

CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism.

1 reference

12 December 2020

NAMPT-Mediated NAD(+) Biosynthesis in Adipocytes Regulates Adipose Tissue Function and Multi-organ Insulin Sensitivity in Mice.

1 reference

12 December 2020

Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle

1 reference

12 December 2020

Head to Head Comparison of Short-Term Treatment with the NAD(+) Precursor Nicotinamide Mononucleotide (NMN) and 6 Weeks of Exercise in Obese Female Mice.

1 reference

12 December 2020

Nicotinamide riboside is uniquely and orally bioavailable in mice and humans

1 reference

12 December 2020

NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells

1 reference

12 December 2020

Nicotinamide adenine dinucleotide biosynthesis promotes liver regeneration.

1 reference

12 December 2020

Simultaneous quantitation of nicotinamide riboside, nicotinamide mononucleotide and nicotinamide adenine dinucleotide in milk by a novel enzyme-coupled assay

1 reference

12 December 2020

Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice

1 reference

12 December 2020

Protection against High-Fat-Diet-Induced Obesity in MDM2C305F Mice Due to Reduced p53 Activity and Enhanced Energy Expenditure.

1 reference

12 December 2020

Effects of a wide range of dietary nicotinamide riboside (NR) concentrations on metabolic flexibility and white adipose tissue (WAT) of mice fed a mildly obesogenic diet.

1 reference

12 December 2020

Inhibition of NAMPT aggravates high fat diet-induced hepatic steatosis in mice through regulating Sirt1/AMPKα/SREBP1 signaling pathway

1 reference

12 December 2020

Kynurenine Pathway of Tryptophan Metabolism: Regulatory and Functional Aspects

1 reference

12 December 2020

Leucine-nicotinic acid synergy stimulates AMPK/Sirt1 signaling and regulates lipid metabolism and lifespan in Caenorhabditis elegans, and hyperlipidemia and atherosclerosis in mice

1 reference

12 December 2020

The first human clinical study for NMN has started in Japan

1 reference

12 December 2020

Kynurenines: Tryptophan's metabolites in exercise, inflammation, and mental health

1 reference

12 December 2020

Modulating NAD+ metabolism, from bench to bedside.

1 reference

12 December 2020

NAD+ in Aging: Molecular Mechanisms and Translational Implications.

1 reference

12 December 2020

Skeletal muscle overexpression of nicotinamide phosphoribosyl transferase in mice coupled with voluntary exercise augments exercise endurance.

1 reference

12 December 2020

Repeat dose NRPT (nicotinamide riboside and pterostilbene) increases NAD+ levels in humans safely and sustainably: a randomized, double-blind, placebo-controlled study

1 reference

12 December 2020

An open-label, non-randomized study of the pharmacokinetics of the nutritional supplement nicotinamide riboside (NR) and its effects on blood NAD+ levels in healthy volunteers.

1 reference

12 December 2020

NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR.

1 reference

12 December 2020

Hepatic NAD+ levels and NAMPT abundance are unaffected during prolonged high-fat diet consumption in C57BL/6JBomTac mice.

1 reference

12 December 2020

Simultaneous Measurement of NAD Metabolome in Aged Mice Tissue Using Liquid Chromatography Tandem-Mass Spectrometry (LC/MS/MS).

1 reference

12 December 2020

The Global Epidemic of the Metabolic Syndrome.

1 reference

12 December 2020

Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence.

1 reference

12 December 2020

Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice.

1 reference

12 December 2020

NAMPT-mediated NAD+ biosynthesis is indispensable for adipose tissue plasticity and development of obesity.

1 reference

12 December 2020

Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults.

1 reference

12 December 2020

Organ Co-Relationship in Tryptophan Metabolism and Factors That Govern the Biosynthesis of Nicotinamide from Tryptophan

1 reference

12 December 2020

A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD Decline

1 reference

12 December 2020

NAD metabolism: Implications in aging and longevity

1 reference

12 December 2020

Overexpression of Nmnat3 efficiently increases NAD and NGD levels and ameliorates age-associated insulin resistance

1 reference

12 December 2020

A randomized placebo-controlled clinical trial of nicotinamide riboside in obese men: safety, insulin-sensitivity, and lipid-mobilizing effects

1 reference

12 December 2020

The Plasma NAD Metabolome Is Dysregulated in "Normal" Aging

1 reference

12 December 2020

Non-alcoholic fatty liver disease: causes, diagnosis, cardiometabolic consequences, and treatment strategies

1 reference

12 December 2020

Macrophage de novo NAD+ synthesis specifies immune function in aging and inflammation

1 reference

12 December 2020

Acute nicotinamide riboside supplementation improves redox homeostasis and exercise performance in old individuals: a double-blind cross-over study

1 reference

12 December 2020

10.1186/S12929-019-0527-8

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31078136%20AND%20SRC:MED&resulttype=core&format=json

25 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31078136%20AND%20SRC:MED&resulttype=core&format=json

25 April 2020

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