(Q64065041)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30964863%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

title

Mitochondrial type II NADH dehydrogenase of Plasmodium falciparum (PfNDH2) is dispensable in the asexual blood stages (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30964863%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

main subject

Plasmodium falciparum

1 reference

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30964863%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

author name string

Suresh M Ganesan

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30964863%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

Swati Dass

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30964863%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

Joanne M Morrisey

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30964863%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

Sovitj Pou

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30964863%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

Aaron Nilsen

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30964863%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

Michael K Riscoe

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30964863%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

Michael W Mather

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30964863%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

Akhil B Vaidya

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30964863%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

language of work or name

English

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publication date

9 April 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30964863%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30964863%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

volume

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30964863%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

issue

4

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2 May 2020

page(s)

e0214023

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Creative Commons Attribution 4.0 International

2 May 2020

copyright license

start time

9 April 2019

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Purification of a reconstitutively active iron-sulfur protein (oxidation factor) from succinate . cytochrome c reductase complex of bovine heart mitochondria

1 reference

12 December 2020

Mitochondria of mammalian Plasmodium spp.

1 reference

12 December 2020

Purification and characterization of a rotenone-insensitive NADH:Q6 oxidoreductase from mitochondria of Saccharomyces cerevisiae

1 reference

12 December 2020

Enzymes of purine and pyrimidine metabolism from the human malaria parasite, Plasmodium falciparum

1 reference

12 December 2020

Phospholipid-cytochrome c interaction: evidence for the extended lipid anchorage

1 reference

12 December 2020

Genome sequence of the human malaria parasite Plasmodium falciparum

1 reference

12 December 2020

Arabidopsis genes encoding mitochondrial type II NAD(P)H dehydrogenases have different evolutionary origin and show distinct responses to light.

1 reference

12 December 2020

HDQ (1-hydroxy-2-dodecyl-4(1H)quinolone), a high affinity inhibitor for mitochondrial alternative NADH dehydrogenase: evidence for a ping-pong mechanism

1 reference

12 December 2020

Functional characterization and target validation of alternative complex I of Plasmodium falciparum mitochondria

1 reference

12 December 2020

Metabolic maps and functions of the Plasmodium mitochondrion

1 reference

12 December 2020

Negative selection using yeast cytosine deaminase/uracil phosphoribosyl transferase in Plasmodium falciparum for targeted gene deletion by double crossover recombination

1 reference

12 December 2020

Growth inhibition of Toxoplasma gondii and Plasmodium falciparum by nanomolar concentrations of 1-hydroxy-2-dodecyl-4(1H)quinolone, a high-affinity inhibitor of alternative (type II) NADH dehydrogenases

1 reference

12 December 2020

Specific role of mitochondrial electron transport in blood-stage Plasmodium falciparum

1 reference

12 December 2020

The malaria parasite type II NADH:quinone oxidoreductase: an alternative enzyme for an alternative lifestyle

1 reference

12 December 2020

The validity of mitochondrial dehydrogenases as antimalarial drug targets.

1 reference

12 December 2020

Malaria-parasite mitochondrial dehydrogenases as drug targets: too early to write the obituary.

1 reference

12 December 2020

A drug-selected Plasmodium falciparum lacking the need for conventional electron transport

1 reference

12 December 2020

Triazolopyrimidine-based dihydroorotate dehydrogenase inhibitors with potent and selective activity against the malaria parasite Plasmodium falciparum.

1 reference

12 December 2020

Identification of new inhibitors for alternative NADH dehydrogenase (NDH-II).

1 reference

12 December 2020

Type II NADH dehydrogenase of the respiratory chain of Plasmodium falciparum and its inhibitors

1 reference

12 December 2020

Chapter 17 Type II NADH: quinone oxidoreductases of Plasmodium falciparum and Mycobacterium tuberculosis kinetic and high-throughput assays.

1 reference

12 December 2020

Hemozoin-free Plasmodium falciparum mitochondria for physiological and drug susceptibility studies.

1 reference

12 December 2020

Variation among Plasmodium falciparum strains in their reliance on mitochondrial electron transport chain function

1 reference

12 December 2020

Arrested oocyst maturation in Plasmodium parasites lacking type II NADH:ubiquinone dehydrogenase

1 reference

12 December 2020

Two internal type II NADH dehydrogenases of Toxoplasma gondii are both required for optimal tachyzoite growth

1 reference

12 December 2020

Cytochrome b mutation Y268S conferring atovaquone resistance phenotype in malaria parasite results in reduced parasite bc1 catalytic turnover and protein expression

1 reference

12 December 2020

Identification, design and biological evaluation of bisaryl quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2).

1 reference

12 December 2020

Identification, design and biological evaluation of heterocyclic quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2).

1 reference

12 December 2020

Identification of novel antimalarial chemotypes via chemoinformatic compound selection methods for a high-throughput screening program against the novel malarial target, PfNDH2: increasing hit rate via virtual screening methods.

1 reference

12 December 2020

HDQ, a potent inhibitor of Plasmodium falciparum proliferation, binds to the quinone reduction site of the cytochrome bc1 complex.

1 reference

12 December 2020

Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria

1 reference

12 December 2020

Critical roles of the mitochondrial complex II in oocyst formation of rodent malaria parasite Plasmodium berghei

1 reference

12 December 2020

Mitochondrial disorders as windows into an ancient organelle

1 reference

12 December 2020

Quinolone-3-diarylethers: a new class of antimalarial drug.

1 reference

12 December 2020

Novel inhibitors of the Plasmodium falciparum electron transport chain

1 reference

12 December 2020

Discovery, synthesis, and optimization of antimalarial 4(1H)-quinolone-3-diarylethers

1 reference

12 December 2020

Mitochondrial ATP synthase is dispensable in blood-stage Plasmodium berghei rodent malaria but essential in the mosquito phase

1 reference

12 December 2020

Genetic investigation of tricarboxylic acid metabolism during the Plasmodium falciparum life cycle

1 reference

12 December 2020

A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria

1 reference

12 December 2020

Parasites resistant to the antimalarial atovaquone fail to transmit by mosquitoes

1 reference

12 December 2020

Atovaquone and ELQ-300 Combination Therapy as a Novel Dual-Site Cytochrome bc1 Inhibition Strategy for Malaria

1 reference

12 December 2020

The chaperonin TRiC forms an oligomeric complex in the malaria parasite cytosol

1 reference

12 December 2020

Target Elucidation by Cocrystal Structures of NADH-Ubiquinone Oxidoreductase of Plasmodium falciparum (PfNDH2) with Small Molecule To Eliminate Drug-Resistant Malaria

1 reference

12 December 2020

Structure and function of complex I in animals and plants - a comparative view

1 reference

12 December 2020

Type-II NADH Dehydrogenase (NDH-2): a promising therapeutic target for antitubercular and antibacterial drug discovery

1 reference

12 December 2020

Suppression of experimental cerebral malaria by disruption of malate:quinone oxidoreductase.

1 reference

12 December 2020

The mitochondrial ribosomal protein L13 is critical for the structural and functional integrity of the mitochondrion in Plasmodium falciparum.

1 reference

12 December 2020

Uncovering the essential genes of the human malaria parasitePlasmodium falciparumby saturation mutagenesis

1 reference

12 December 2020

Selection of cytochrome B mutants by putative PfNDH2 inhibitors

1 reference

12 December 2020

Antimalarial activity of single-dose DSM265, a novel plasmodium dihydroorotate dehydrogenase inhibitor, in patients with uncomplicated Plasmodium falciparum or Plasmodium vivax malaria infection: a proof-of-concept, open-label, phase 2a study

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0214023

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30964863%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30964863%20AND%20SRC:MED&resulttype=core&format=json

2 May 2020

PubMed publication ID

30964863

1 reference