(Q64112523)

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Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets

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scholarly article

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Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets (English)

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object named as

Andrew H Sims

3

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16

object named as

Paul T Spellman

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author name string

Luca Cassetta

1

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Stamatina Fragkogianni

2

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Agnieszka Swierczak

4

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Lesley M Forrester

5

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Hui Zhang

6

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Daniel Y H Soong

7

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Tiziana Cotechini

8

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Pavana Anur

9

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Elaine Y Lin

10

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Antonella Fidanza

11

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Martha Lopez-Yrigoyen

12

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Michael R Millar

13

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Alexandra Urman

14

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Zhichao Ai

15

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E Shelley Hwang

17

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J Michael Dixon

18

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Lisa Wiechmann

19

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Lisa M Coussens

20

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Harriet O Smith

21

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Jeffrey W Pollard

22

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language of work or name

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publication date

15 April 2019

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35

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4

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588-602.e10

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describes a project that uses

object named as

limma

Limma

2 references

Europe PubMed Central

22 June 2022

https://europepmc.org/article/PMC/6472943

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inferred from PubMed Central ID database lookup

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

object named as

affy package

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CZ Software Mentions: A large dataset of software mentions in the biomedical literature

ROCR: visualizing classifier performance in R

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https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adjusting batch effects in microarray expression data using empirical Bayes methods

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Significance of interleukin-6 (IL-6) in breast cancer (review).

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simultaneous visualization of multiple antigens with tyramide signal amplification using antibodies from the same species

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro

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https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mesenchymal stem cells within tumour stroma promote breast cancer metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stromal gene expression predicts clinical outcome in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The macrophage colony-stimulating factor 1 response signature in breast carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Supervised risk predictor of breast cancer based on intrinsic subtypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

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Patterns of MMP-2 and MMP-9 expression in human cancer cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

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A scaling normalization method for differential expression analysis of RNA-seq data

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD16+ monocytes in breast cancer patients: expanded by monocyte chemoattractant protein-1 and may be useful for early diagnosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improving RNA-Seq expression estimates by correcting for fragment bias

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

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CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PrimerBank: a PCR primer database for quantitative gene expression analysis, 2012 update

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

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The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CCL2/CCR2 chemokine signaling coordinates survival and motility of breast cancer cells through Smad3 protein- and p42/44 mitogen-activated protein kinase (MAPK)-dependent mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

STAR: ultrafast universal RNA-seq aligner

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

M1 polarization of human monocyte-derived macrophages restricts pre and postintegration steps of HIV-1 replication.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trimmomatic: a flexible trimmer for Illumina sequence data

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cellular and molecular origin of tumor-associated macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

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HTSeq--a Python framework to work with high-throughput sequencing data

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-10 enhances the phenotype of M2 macrophages induced by IL-4 and confers the ability to increase eosinophil migration

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

svaseq: removing batch effects and other unwanted noise from sequencing data

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular profiling reveals a tumor-promoting phenotype of monocytes and macrophages in human cancer progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

limma powers differential expression analyses for RNA-sequencing and microarray studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CCL2-induced chemokine cascade promotes breast cancer metastasis by enhancing retention of metastasis-associated macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Much More than M1 and M2 Macrophages, There are also CD169(+) and TCR(+) Macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The prognostic landscape of genes and infiltrating immune cells across human cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intestinal CD169(+) macrophages initiate mucosal inflammation by secreting CCL8 that recruits inflammatory monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The importance of microenvironment: the role of CCL8 in metastasis formation of melanoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

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Patrolling monocytes control tumor metastasis to the lung.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

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A Higher Frequency of CD14+ CD169+ Monocytes/Macrophages in Patients with Colorectal Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor-associated macrophages: unwitting accomplices in breast cancer malignancy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

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CD169 identifies an anti-tumour macrophage subpopulation in human hepatocellular carcinoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A CCL8 gradient drives breast cancer cell dissemination

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of Mouse and Human Tumor-Associated Macrophages.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of tumor-associated macrophages in human malignancies: friend or foe?

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maraviroc decreases CCL8-mediated migration of CCR5(+) regulatory T cells and reduces metastatic tumor growth in the lungs

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulatory T Cells Exhibit Distinct Features in Human Breast Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of KLF1 Enhances the Differentiation and Maturation of Red Blood Cells from Human Pluripotent Stem Cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative Multiplex Immunohistochemistry Reveals Myeloid-Inflamed Tumor-Immune Complexity Associated with Poor Prognosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

C-C motif chemokine receptor 1 (CCR1) is a target of the EGF-AKT-mTOR-STAT3 signaling axis in breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T cell-induced CSF1 promotes melanoma resistance to PD1 blockade.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pan-cancer landscape of interactions between solid tumors and infiltrating immune cell populations.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

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A Unidirectional Transition from Migratory to Perivascular Macrophage Is Required for Tumor Cell Intravasation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

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A human iPSC line capable of differentiating into functional macrophages expressing ZsGreen: a tool for the study and in vivo tracking of therapeutic cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

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Diverse Functions of Macrophages in Different Tumor Microenvironments

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

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Targeting macrophages: therapeutic approaches in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30930117

12 December 2020

based on heuristic

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Identifiers

10.1016/J.CCELL.2019.02.009

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