(Q64115578)

12 December 2020

Nuclear localization and regulation of erk- and rsk-encoded protein kinases

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12 December 2020

Identification of the regulatory phosphorylation sites in pp42/mitogen-activated protein kinase (MAP kinase)

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12 December 2020

Epidermal growth factor induced tyrosine phosphorylation of nuclear proteins associated with translocation of epidermal growth factor receptor into the nucleus

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12 December 2020

The Mos/MAP kinase pathway stabilizes c-Fos by phosphorylation and augments its transforming activity in NIH 3T3 cells

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12 December 2020

Nuclear translocation of beta II PKC isoenzyme in phorbol ester-stimulated KM-3 pre-B human leukemic cells.

1 reference

12 December 2020

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

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12 December 2020

Functional divergence of the MAP kinase pathway. ERK1 and ERK2 activate specific transcription factors

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12 December 2020

Selective nuclear translocation of protein kinase C alpha in Swiss 3T3 cells treated with IGF-I, PDGF and EGF.

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12 December 2020

Point mutations in the c-Myc transactivation domain are common in Burkitt's lymphoma and mouse plasmacytomas

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12 December 2020

Phosphorylation of the c-Fos transrepression domain by mitogen-activated protein kinase and 90-kDa ribosomal S6 kinase

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12 December 2020

Site-specific modulation of c-Myc cotransformation by residues phosphorylated in vivo.

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12 December 2020

Phosphorylation of c-Fos at the C-terminus enhances its transforming activity.

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12 December 2020

Tob, a novel protein that interacts with p185erbB2, is associated with anti-proliferative activity

1 reference

12 December 2020

Endothelial cell tyrosine kinase receptor and G protein-coupled receptor activation involves distinct protein kinase C isoforms

1 reference

12 December 2020

Nuclear translocation of mitogen-activated protein kinase kinase (MEK1) in response to mitogenic stimulation

1 reference

12 December 2020

TPA induces translocation but not down-regulation of new PKC isoform eta in macrophages, MDCK cells and astrocytes

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12 December 2020

Cellular relocalisation of protein kinase C-theta caused by staurosporine and some of its analogues

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12 December 2020

Nuclear localization signal-independent and importin/karyopherin-independent nuclear import of beta-catenin

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12 December 2020

Nuclear export of the stress-activated protein kinase p38 mediated by its substrate MAPKAP kinase-2

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12 December 2020

Cloning and characterization of DYRK1B, a novel member of the DYRK family of protein kinases

1 reference

12 December 2020

Identification of a cytoplasmic-retention sequence in ERK2

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12 December 2020

Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

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12 December 2020

ERK5 is a novel type of mitogen-activated protein kinase containing a transcriptional activation domain

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12 December 2020

Involvement of the activation loop of ERK in the detachment from cytosolic anchoring

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12 December 2020

PEA-15 mediates cytoplasmic sequestration of ERK MAP kinase

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12 December 2020

An immediate response of ribosomal transcription to growth factor stimulation in mammals is mediated by ERK phosphorylation of UBF

1 reference

12 December 2020

Phosphorylation of three regulatory serines of Tob by Erk1 and Erk2 is required for Ras-mediated cell proliferation and transformation

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12 December 2020

The specificity of extracellular signal-regulated kinase 2 dephosphorylation by protein phosphatases

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12 December 2020

Molecular interpretation of ERK signal duration by immediate early gene products

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12 December 2020

Regulation of MAP Kinase Signaling Modules by Scaffold Proteins in Mammals

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12 December 2020

Alteration of expression or phosphorylation status of tob, a novel tumor suppressor gene product, is an early event in lung cancer

1 reference

12 December 2020

AP-1: a double-edged sword in tumorigenesis

1 reference

12 December 2020

The death effector domain protein PEA-15 prevents nuclear entry of ERK2 by inhibiting required interactions.

1 reference

12 December 2020

A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells

1 reference

12 December 2020

MEK5 and ERK5 are localized in the nuclei of resting as well as stimulated cells, while MEKK2 translocates from the cytosol to the nucleus upon stimulation

1 reference

12 December 2020

Subcellular localization determines the protective effects of activated ERK2 against distinct apoptogenic stimuli in myeloid leukemia cells.

1 reference

12 December 2020

Signaling to NF-kappaB

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12 December 2020

Protein-protein interactions in the regulation of the extracellular signal-regulated kinase

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12 December 2020

Activation of either ERK1/2 or ERK5 MAP kinase pathways can lead to disruption of the actin cytoskeleton

1 reference

12 December 2020

Manipulation of redox signaling in mammalian cells enabled by controlled photogeneration of reactive oxygen species.

1 reference

12 December 2020

Transcriptional regulation and transformation by Myc proteins

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12 December 2020

Coordinating ERK/MAPK signalling through scaffolds and inhibitors

1 reference

12 December 2020

The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions

1 reference

12 December 2020

Regulation of nuclear translocation of extracellular signal-regulated kinase 5 by active nuclear import and export mechanisms.

1 reference

12 December 2020

Growth factor signaling regulates elongation of RNA polymerase I transcription in mammals via UBF phosphorylation and r-chromatin remodeling

1 reference

12 December 2020

Smad3-dependent nuclear translocation of beta-catenin is required for TGF-beta1-induced proliferation of bone marrow-derived adult human mesenchymal stem cells

1 reference

12 December 2020

MAPK signalling: ERK5 versus ERK1/2.

1 reference

12 December 2020

Human tumor suppressor p14ARF negatively regulates rRNA transcription and inhibits UBF1 transcription factor phosphorylation.

1 reference

12 December 2020

Jun NH2-terminal kinase (JNK) prevents nuclear beta-catenin accumulation and regulates axis formation in Xenopus embryos

1 reference

12 December 2020

The MEK/ERK cascade: from signaling specificity to diverse functions

1 reference

12 December 2020

Differential regulation and properties of MAPKs

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12 December 2020

Aberrant expression of extracellular signal-regulated kinase 5 in human prostate cancer

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12 December 2020

ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

1 reference

12 December 2020

ERK and MDM2 prey on FOXO3a.

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12 December 2020

Mechanisms of MYC stabilization in human malignancies

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12 December 2020

The roles of MAPKs in disease

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12 December 2020

Identification and characterization of a general nuclear translocation signal in signaling proteins

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12 December 2020

Reflecting on 25 years with MYC.

1 reference

12 December 2020

Dual-specificity phosphatases: critical regulators with diverse cellular targets

1 reference

12 December 2020

Extracellular signal-regulated kinase 2-dependent phosphorylation induces cytoplasmic localization and degradation of p21Cip1.

1 reference

12 December 2020

The subcellular localization of MEK and ERK--a novel nuclear translocation signal (NTS) paves a way to the nucleus

1 reference

12 December 2020

The ERK signaling cascade--views from different subcellular compartments

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12 December 2020

Signal integration by JNK and p38 MAPK pathways in cancer development

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12 December 2020

c-Jun N-terminal kinase (JNK) signaling: recent advances and challenges.

1 reference

12 December 2020

Pathological roles of MAPK signaling pathways in human diseases

1 reference

12 December 2020

Mechanisms regulating the nuclear translocation of p38 MAP kinase

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12 December 2020

The MAP Kinase Signaling Cascades: A System of Hundreds of Components Regulates a Diverse Array of Physiological Functions

1 reference

12 December 2020

Calcium regulation of EGF-induced ERK5 activation: role of Lad1-MEKK2 interaction

1 reference

12 December 2020

Pharmacological inhibition of BMK1 suppresses tumor growth through promyelocytic leukemia protein

1 reference

12 December 2020

Molecular basis for specificity of nuclear import and prediction of nuclear localization

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12 December 2020

The MAPK cascades: signaling components, nuclear roles and mechanisms of nuclear translocation

1 reference

12 December 2020

ERK5 signalling in prostate cancer promotes an invasive phenotype

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12 December 2020

Resistance to BRAF inhibition in melanomas

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12 December 2020

Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases

1 reference

12 December 2020

Nuclear import of early growth response-1 involves importin-7 and the novel nuclear localization signal serine-proline-serine.

1 reference

12 December 2020

RETRACTED: Nuclear Extracellular Signal-Regulated Kinase 1 and 2 Translocation Is Mediated by Casein Kinase 2 and Accelerated by Autophosphorylation

1 reference

12 December 2020

The ERK Cascade: Distinct Functions within Various Subcellular Organelles

1 reference

12 December 2020

Working without kinase activity: phosphotransfer-independent functions of extracellular signal-regulated kinases

1 reference

12 December 2020

ERK1/2 MAP kinases: structure, function, and regulation

1 reference

12 December 2020

The many faces and functions of β-catenin

1 reference

12 December 2020

Immediate early response genes and cell transformation

1 reference

12 December 2020

Role of big mitogen-activated protein kinase 1 (BMK1) / extracellular signal-regulated kinase 5 (ERK5) in the pathogenesis and progression of atherosclerosis

1 reference

12 December 2020

Wnt/β-catenin signalling: from plasma membrane to nucleus

1 reference

12 December 2020

Dual inactivation of Akt and ERK by TIC10 signals Foxo3a nuclear translocation, TRAIL gene induction, and potent antitumor effects

1 reference

12 December 2020

Canonical and kinase activity-independent mechanisms for extracellular signal-regulated kinase 5 (ERK5) nuclear translocation require dissociation of Hsp90 from the ERK5-Cdc37 complex

1 reference

12 December 2020

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12 December 2020

Mitogen-activated protein kinases in innate immunity

1 reference

12 December 2020

Stimulated nuclear import by β-like importins

1 reference

12 December 2020

RETRACTED: Beta-like importins mediate the nuclear translocation of mitogen-activated protein kinases

1 reference

12 December 2020

TNF and MAP kinase signalling pathways

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12 December 2020

Targeting the β-catenin nuclear transport pathway in cancer

1 reference

12 December 2020

Nuclear to cytoplasmic shuttling of ERK promotes differentiation of muscle stem/progenitor cells.

1 reference

12 December 2020

Targeting RAF kinases for cancer therapy: BRAF-mutated melanoma and beyond

1 reference

12 December 2020

Antitumor activity of the ERK inhibitor SCH772984 [corrected] against BRAF mutant, NRAS mutant and wild-type melanoma

1 reference

12 December 2020

The role of ERK5 in endothelial cell function.

1 reference

12 December 2020

Roles of p38α mitogen-activated protein kinase in mouse models of inflammatory diseases and cancer.

1 reference

12 December 2020

The nuclear translocation of ERK1/2 as an anticancer target.

1 reference

12 December 2020

Aberrant MEK5/ERK5 signalling contributes to human colon cancer progression via NF-κB activation

1 reference

12 December 2020

Identification of DYRK1B as a substrate of ERK1/2 and characterisation of the kinase activity of DYRK1B mutants from cancer and metabolic syndrome.

1 reference

12 December 2020

The Stress Kinase p38α as a Target for Cancer Therapy

1 reference

12 December 2020

MEK1 and MEK2 inhibitors and cancer therapy: the long and winding road

1 reference

12 December 2020

Beyond β-catenin: prospects for a larger catenin network in the nucleus

1 reference

12 December 2020

The dynamic subcellular localization of ERK: mechanisms of translocation and role in various organelles

1 reference

12 December 2020

The ERK cascade inhibitors: Towards overcoming resistance

1 reference

12 December 2020

JNK Signaling: Regulation and Functions Based on Complex Protein-Protein Partnerships

1 reference

12 December 2020

ERK5 and Cell Proliferation: Nuclear Localization Is What Matters

1 reference

12 December 2020

Direct binding of MEK1 and MEK2 to AKT induces Foxo1 phosphorylation, cellular migration and metastasis

1 reference

12 December 2020

A compendium of ERK targets

1 reference

12 December 2020

Decreased TOB1 expression and increased phosphorylation of nuclear TOB1 promotes gastric cancer

1 reference

12 December 2020

Combined inhibition of MEK and nuclear ERK translocation has synergistic antitumor activity in melanoma cells.

1 reference

12 December 2020

A wake-up call to quiescent cancer cells - potential use of DYRK1B inhibitors in cancer therapy

1 reference

12 December 2020

RAPGEF5 Regulates Nuclear Translocation of β-Catenin.

1 reference

12 December 2020

ERK1/2 inhibitors: New weapons to inhibit the RAS-regulated RAF-MEK1/2-ERK1/2 pathway.

1 reference

12 December 2020

Development of MK-8353, an orally administered ERK1/2 inhibitor, in patients with advanced solid tumors.

1 reference

12 December 2020

RAS-mediated oncogenic signaling pathways in human malignancies.

1 reference

12 December 2020

Extracellular-Regulated Kinases: Signaling From Ras to ERK Substrates to Control Biological Outcomes.

1 reference

12 December 2020

Mitogen-activated protein kinase inhibitors reduce the nuclear accumulation of phosphorylated Smads by inhibiting Imp 7 or Imp 8 in HepG2 cells.

1 reference

12 December 2020

Signaling Pathways In Inflammation And Anti-Inflammatory Therapies.

1 reference

12 December 2020

Oncogenic Signaling Pathways in The Cancer Genome Atlas.

1 reference

12 December 2020

The nuclear translocation of the kinases p38 and JNK promotes inflammation-induced cancer.

1 reference

12 December 2020

MTBP inhibits the Erk1/2-Elk-1 signaling in hepatocellular carcinoma.

1 reference

12 December 2020

Targeting ERK, an Achilles' Heel of the MAPK pathway, in cancer therapy

1 reference

12 December 2020

Targeting oncogenic Raf protein-serine/threonine kinases in human cancers

1 reference

12 December 2020

The Nuclear Translocation of Mitogen-Activated Protein Kinases: Molecular Mechanisms and Use as Novel Therapeutic Target

1 reference

12 December 2020

Dual-specificity MAP kinase phosphatases in health and disease

1 reference

12 December 2020