(Q64379909)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21350582%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

title

Enhancement of CPT-11 antitumor activity by adenovirus-mediated expression of β-glucuronidase in tumors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21350582%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference

P-T Huang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21350582%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

K-C Chen

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21350582%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Z M Prijovich

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21350582%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

T-L Cheng

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21350582%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Y-L Leu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21350582%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

S R Roffler

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21350582%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

language of work or name

English

0 references

publication date

25 February 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21350582%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21350582%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

volume

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21350582%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21350582%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

page(s)

381-389

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21350582%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/cgt.2011.3

23 January 2020

exact match

0 references

cites work

Phase II study of sequentially administered low-dose mitomycin-C (MMC) and irinotecan (CPT-11) in women with metastatic breast cancer (MBC).

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

The topoisomerase I poison CPT-11 enhances the effect of the aurora B kinase inhibitor AZD1152 both in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Cisplatin plus weekly CPT-11/docetaxel in advanced esophagogastric cancer: a phase I study with pharmacogenetic assessment of XPD, XRCC3 and UGT1A1 polymorphisms

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Metabolic activation of CPT-11, 7-ethyl-10-[4-(1-piperidino)-1- piperidino]carbonyloxycamptothecin, a novel antitumor agent, by carboxylesterase

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Conversion of irinotecan (CPT-11) to its active metabolite, 7-ethyl-10-hydroxycamptothecin (SN-38), by Human Liver Carboxylesterase

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Pharmacokinetics of irinotecan and its metabolites in human blood, bile, and urine

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Pharmacokinetic and pharmacogenetic determinants of the activity and toxicity of irinotecan in metastatic colorectal cancer patients

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Introduction to the background, principles, and state of the art in suicide gene therapy.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

In vivo human carboxylesterase cDNA gene transfer to activate the prodrug CPT-11 for local treatment of solid tumors

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

A novel doxorubicin-glucuronide prodrug DOX-GA3 for tumour-selective chemotherapy: distribution and efficacy in experimental human ovarian cancer

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Anti-tumour activity and toxicity of the new prodrug 9-aminocamptothecin glucuronide (9ACG) in mice

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Characterization of an antineoplastic glucuronide prodrug

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Secreted human beta-glucuronidase: a novel tool for gene-directed enzyme prodrug therapy

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Membrane-tethered proteins for basic research, imaging, and therapy.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Cell surface display of a lysosomal enzyme for extracellular gene-directed enzyme prodrug therapy

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Membrane-localized activation of glucuronide prodrugs by beta-glucuronidase enzymes

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Local enzymatic hydrolysis of an endogenously generated metabolite can enhance CPT-11 anticancer efficacy

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Targeted cancer gene therapy: the flexibility of adenoviral gene therapy vectors

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Gene expression in intrahepatic tumors through DNA recombination by a replication-activated adenovirus vector

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Transductional targeting of adenovirus vectors for gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

A phase I/II clinical trial in localized prostate cancer of an adenovirus expressing nitroreductase with CB1954 [correction of CB1984].

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Selection of invasive and metastatic subpopulations from a human lung adenocarcinoma cell line

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Markers of neoplastic transformation in epithelial cell lines derived from human carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

A membrane antibody receptor for noninvasive imaging of gene expression.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Efficient gene transfer into human CD34(+) cells by a retargeted adenovirus vector

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Tumor-specific gene expression in hepatic metastases by a replication-activated adenovirus vector

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Phase I and biodistribution study of recombinant adenovirus vector-mediated herpes simplex virus thymidine kinase gene and ganciclovir administration in patients with head and neck cancer and other malignant tumors

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Bacterial Cytosine Deaminase Mutants Created by Molecular Engineering Show Improved 5-Fluorocytosine-Mediated Cell Killing In vitro and In vivo

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Systemic gene-directed enzyme prodrug therapy of hepatocellular carcinoma using a targeted adenovirus armed with carboxypeptidase G2.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Gene expression imaging by enzymatic catalysis of a fluorescent probe via membrane-anchored beta-glucuronidase

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Design of transgenes for efficient expression of active chimeric proteins on mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Bystander or no bystander for gene directed enzyme prodrug therapy

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Antiangiogenesis targeting tumor microenvironment synergizes glucuronide prodrug antitumor activity

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Micro-PET imaging of beta-glucuronidase activity by the hydrophobic conversion of a glucuronide probe

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

The importance of tumor glucuronidase in the activation of irinotecan in a mouse xenograft model.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Directed evolution of a lysosomal enzyme with enhanced activity at neutral pH by mammalian cell-surface display

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Tumor-targeting prodrug-activating bacteria for cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

An improved human carboxylesterase for enzyme/prodrug therapy with CPT-11.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Tumor-targeted enzyme/prodrug therapy mediates long-term disease-free survival of mice bearing disseminated neuroblastoma

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2011.3

7 January 2021

Identifiers

DOI

10.1038/CGT.2011.3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21350582%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference