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Tumor-derived mutations within the DNA-binding domain of p53 that phenotypically resemble the deletion of the proline-rich domain
scientific article published on 01 March 2000
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Europe PubMed Central
PubMed publication ID
10777217
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10777217%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
title
Tumor-derived mutations within the DNA-binding domain of p53 that phenotypically resemble the deletion of the proline-rich domain
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10777217
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10777217%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
author
Philipp Koch
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2
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Europe PubMed Central
PubMed publication ID
10777217
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10777217%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
Matthias Dobbelstein
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4
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Europe PubMed Central
PubMed publication ID
10777217
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10777217%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
author name string
J Roth
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1
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Europe PubMed Central
PubMed publication ID
10777217
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10777217%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
A Contente
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3
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Europe PubMed Central
PubMed publication ID
10777217
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10777217%20AND%20SRC:MED&resulttype=core&format=json
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6 November 2019
language of work or name
English
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publication date
1 March 2000
1 reference
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Europe PubMed Central
PubMed publication ID
10777217
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10777217%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
published in
Oncogene
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stated in
Europe PubMed Central
PubMed publication ID
10777217
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10777217%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
volume
19
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Europe PubMed Central
PubMed publication ID
10777217
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10777217%20AND%20SRC:MED&resulttype=core&format=json
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6 November 2019
issue
14
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Europe PubMed Central
PubMed publication ID
10777217
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10777217%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
page(s)
1834-1842
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10777217
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10777217%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
exact match
https://scigraph.springernature.com/pub.10.1038/sj.onc.1203500
0 references
cites work
Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic selection of intragenic suppressor mutations that reverse the effect of common p53 cancer mutations
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protection against apoptosis by the vaccinia virus SPI-2 (B13R) gene product
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted alpha helices: crystal structure of the protein-DNA complex
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A genetic approach to mapping the p53 binding site in the MDM2 protein
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
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7 January 2021
based on heuristic
inferred from DOI database lookup
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 tumor suppressor gene: from the basic research laboratory to the clinic--an abridged historical perspective
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sequence requirements for coiled-coils: analysis with lambda repressor-GCN4 leucine zipper fusions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of the specific DNA binding function of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High mobility group protein-1 (HMG-1) is a unique activator of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of redox/repair protein Ref-1 as a potent activator of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p73 is a simian [correction of human] p53-related protein that can induce apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The emerging p53 gene family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adenovirus type 5 E4orf3 protein relieves p53 inhibition by E1B-55-kilodalton protein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53, the cellular gatekeeper for growth and division
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Semirational design of active tumor suppressor p53 DNA binding domain with enhanced stability
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sequence-specific transcriptional activation is essential for growth suppression by p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A model for p53-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 codon 72 polymorphism and risk of cervical cancer in UK.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A proline-rich motif in p53 is required for transactivation-independent growth arrest as induced by Gas1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrest
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The polyproline region of p53 is required to activate apoptosis but not growth arrest.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
c-Abl neutralizes the inhibitory effect of Mdm2 on p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of a p53 polymorphism in the development of human papillomavirus-associated cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two polymorphic variants of wild-type p53 differ biochemically and biologically
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional domains of wild-type and mutant p53 proteins involved in transcriptional regulation, transdominant inhibition, and transformation suppression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a novel p53 functional domain that is necessary for efficient growth suppression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA damage enables p73
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification and classification of p53-regulated genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential regulation of cellular target genes by p53 devoid of the PXXP motifs with impaired apoptotic activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1203500
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.ONC.1203500
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10777217
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10777217%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
Dimensions Publication ID
1003902928
0 references
PubMed publication ID
10777217
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10777217
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10777217%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 November 2019
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