(Q74272524)

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The 399Gln polymorphism in the DNA repair gene XRCC1 modulates the genotoxic response induced in human lymphocytes by the tobacco-specific nitrosamine NNK

scientific article published on 01 October 2000

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9 November 2019

The 399Gln polymorphism in the DNA repair gene XRCC1 modulates the genotoxic response induced in human lymphocytes by the tobacco-specific nitrosamine NNK (English)

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9 November 2019

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S Z Abdel-Rahman

1

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9 November 2019

R A El-Zein

2

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9 November 2019

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1 October 2000

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9 November 2019

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9 November 2019

159

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9 November 2019

63-71

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9 November 2019

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9 November 2019

Metabolic activation and detoxification of tobacco-specific nitrosamines--a model for cancer prevention strategies

1 reference

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Oxygen radicals potentiate the genetic toxicity of tobacco-specific nitrosamines

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Modulation of DNA repair by various inhibitors of DNA synthesis following 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induced DNA damage

1 reference

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Recent studies on mechanisms of bioactivation and detoxification of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a tobacco-specific lung carcinogen

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Symposium overview: the role of genetic polymorphism and repair deficiencies in environmental disease.

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Polymorphisms of DNA repair gene XRCC1 in squamous cell carcinoma of the head and neck

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DNA-mediated transfer of a human DNA repair gene that controls sister chromatid exchange

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Molecular cloning of the human XRCC1 gene, which corrects defective DNA strand break repair and sister chromatid exchange

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XRCC1 polypeptide interacts with DNA polymerase beta and possibly poly (ADP-ribose) polymerase, and DNA ligase III is a novel molecular 'nick-sensor' in vitro

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Role of GSTT1 and GSTM1 genotypes in determining individual sensitivity to sister chromatid exchange induction by diepoxybutane in cultured human lymphocytes.

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Role of polymorphic CYP2E1 and CYP2D6 genes in NNK-induced chromosome aberrations in cultured human lymphocytes

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Molecular interaction of [2,3-14C] acrylonitrile with DNA in gastric tissue of rat

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Cytological detection of mutagen-carcinogen exposure by sister chromatid exchange

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Both cross-links and monoadducts induced in DNA by psoralens can lead to sister chromatid exchange formation

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Inhibitory action of melatonin on H2O2- and cyclophosphamide-induced DNA damage

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Modulation by glutathione of DNA strand breaks induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and its aldehyde metabolites in rat hepatocytes

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Formaldehyde-induced sister chromatid exchanges in vitro and the influence of the exogenous metabolizing systems S9 mix and primary rat hepatocytes

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7 January 2021

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DNA adduct formation from tobacco-specific N-nitrosamines

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1 reference

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7 January 2021

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XRCC1 keeps DNA from getting stranded

1 reference

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7 January 2021

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XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage

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Mutations in hamster single-strand break repair gene XRCC1 causing defective DNA repair

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Construction of human XRCC1 minigenes that fully correct the CHO DNA repair mutant EM9

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Identifiers

10.1016/S0304-3835(00)00532-2

1 reference

Europe PubMed Central

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9 November 2019

1 reference

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9 November 2019

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