(Q75224003)

English

Exploring the quantitative relationship between the level of MDR1 transcript, protein and function using digoxin as a marker of MDR1-dependent drug efflux activity

scientific article published on 01 January 2004

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scholarly article

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Europe PubMed Central

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17 November 2019

Exploring the quantitative relationship between the level of MDR1 transcript, protein and function using digoxin as a marker of MDR1-dependent drug efflux activity (English)

1 reference

Europe PubMed Central

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17 November 2019

author name string

Jan Taipalensuu

1

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17 November 2019

Staffan Tavelin

2

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17 November 2019

Lucia Lazorova

3

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17 November 2019

Ann-Cathrin Svensson

4

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17 November 2019

Per Artursson

5

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17 November 2019

publication date

1 January 2004

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17 November 2019

European Journal of Pharmaceutical Sciences

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17 November 2019

21

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17 November 2019

69-75

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17 November 2019

1

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17 November 2019

Multidrug resistance gene (mdr1) RNA levels in relation to P-glycoprotein content of leukemic cells from patients with acute leukemia.

1 reference

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Functional multidrug resistance protein (MRP1) lacking the N-terminal transmembrane domain

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Ubiquitin-mediated proteolysis: biological regulation via destruction

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Vectorial transport by double-transfected cells expressing the human uptake transporter SLC21A8 and the apical export pump ABCC2.

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Reversal of resistance by GF120918 in cell lines expressing the ABC half-transporter, MXR.

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Post-transcriptional gene regulatory mechanisms in eukaryotes: an overview.

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The human ATP-binding cassette (ABC) transporter superfamily

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Increased bioavailability of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in MRP2-deficient rats.

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Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA

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Relevance of p-glycoprotein for the enteral absorption of cyclosporin A: in vitro-in vivo correlation

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Multidrug resistance in cancer: role of ATP-dependent transporters

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The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin

1 reference

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Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

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Role of breast cancer resistance protein in the bioavailability and fetal penetration of topotecan

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Experimentally induced changes in the endocytic traffic of P-glycoprotein alter drug resistance of cancer cells

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Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide

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Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver

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Transcription of eukaryotic protein-coding genes

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Transport function and hepatocellular localization of mrp6 in rat liver

1 reference

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7 January 2021

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Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdr 1a P-glycoprotein

1 reference

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7 January 2021

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A genomic view of alternative splicing

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7 January 2021

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P-glycoprotein-mediated transport of digitoxin, alpha-methyldigoxin and beta-acetyldigoxin

1 reference

https://api.crossref.org/works/10.1016%2FS0928-0987%2803%2900204-5

7 January 2021

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Translation control: bridging the gap between genomics and proteomics?

1 reference

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7 January 2021

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Resolution of P-glycoprotein and non-P-glycoprotein effects on drug permeability using intestinal tissues from mdr1a (-/-) mice.

1 reference

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7 January 2021

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Relationship between mRNA levels quantified by reverse transcription-competitive PCR and metabolic activity of CYP3A4 and CYP2E1 in human liver

1 reference

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Multidrug resistance transporters and modulation

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Role of P-glycoprotein and cytochrome P450 3A in limiting oral absorption of peptides and peptidomimetics

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Identifiers

10.1016/S0928-0987(03)00204-5

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14706813%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14706813%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

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