(Q78192930)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10467417%20AND%20SRC:MED&resulttype=core&format=json

12 December 2019

title

Anti-apoptotic activity of p53 maps to the COOH-terminal domain and is retained in a highly oncogenic natural mutant (English)

1 reference

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12 December 2019

1 reference

5

1 reference

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12 December 2019

Urszula Hibner

7

1 reference

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12 December 2019

author name string

Lassus P

1

1 reference

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12 December 2019

Bertrand C

2

1 reference

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12 December 2019

Zugasti O

3

1 reference

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12 December 2019

Chambon JP

4

1 reference

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12 December 2019

Mathieu-Mahul D

6

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12 December 2019

language of work or name

English

0 references

publication date

1 August 1999

1 reference

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12 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10467417%20AND%20SRC:MED&resulttype=core&format=json

12 December 2019

volume

18

1 reference

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12 December 2019

issue

33

1 reference

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12 December 2019

page(s)

4699-4709

1 reference

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p53 in signaling checkpoint arrest or apoptosis

12 December 2019

cites work

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Tissue-specific inactivation of p53 tumor suppression in the mouse

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p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

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Growth factor modulation of p53-mediated growth arrest versus apoptosis

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p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells

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7 January 2021

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

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Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

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7 January 2021

Gain of function mutations in p53.

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Wild-type p53 activates transcription in vitro

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7 January 2021

HSP70 Binding Sites in the Tumor Suppressor Protein p53

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In vitro establishment is not a sufficient prerequisite for transformation by activated ras oncogenes.

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A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis

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Regulation of mutant p53 temperature-sensitive DNA binding.

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Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

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7 January 2021

Transgenic mouse model for studying the transcriptional activity of the p53 protein: age- and tissue-dependent changes in radiation-induced activation during embryogenesis

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7 January 2021

Biochemical properties and biological effects of p53.

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7 January 2021

Database of p53 gene somatic mutations in human tumors and cell lines: updated compilation and future prospects

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7 January 2021

p53; from inductive signal to cellular effect

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7 January 2021

Allosteric regulation of the thermostability and DNA binding activity of human p53 by specific interacting proteins. CRC Cell Transformation Group

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7 January 2021

p53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts

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7 January 2021

Induction of apoptosis in HeLa cells by trans-activation-deficient p53

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7 January 2021

14-3-3sigma is a p53-regulated inhibitor of G2/M progression

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7 January 2021

Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression

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7 January 2021

Allosteric activation of latent p53 tetramers

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7 January 2021

Regulation of the specific DNA binding function of p53

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7 January 2021

Activation of the cryptic DNA binding function of mutant forms of p53.

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7 January 2021

Small peptides activate the latent sequence-specific DNA binding function of p53.

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7 January 2021

Identification of redox/repair protein Ref-1 as a potent activator of p53

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7 January 2021

Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors.

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7 January 2021

Oncogenic forms of p53 inhibit p53-regulated gene expression

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7 January 2021

p53: puzzle and paradigm

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7 January 2021

Transgenic mice with p53-responsive lacZ: p53 activity varies dramatically during normal development and determines radiation and drug sensitivity in vivo

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7 January 2021

Detection and quantification of apoptosis in transiently transfected adherent cells

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7 January 2021

p53, the cellular gatekeeper for growth and division

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7 January 2021

Differential activation of target cellular promoters by p53 mutants with impaired apoptotic function

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7 January 2021

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7 January 2021

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

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7 January 2021

Role of the Human Heat Shock Protein hsp70 in Protection against Stress-Induced Apoptosis

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7 January 2021

Wild-type p53 negatively regulates the expression of a microtubule-associated protein

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7 January 2021

Analysis of the most representative tumour-derived p53 mutants reveals that changes in protein conformation are not correlated with loss of transactivation or inhibition of cell proliferation.

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7 January 2021

Sequence-specific transcriptional activation is essential for growth suppression by p53.

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7 January 2021

Mitochondria are selective targets for the protective effects of heat shock against oxidative injury

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7 January 2021

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7 January 2021

A model for p53-induced apoptosis

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7 January 2021

A proline-rich motif in p53 is required for transactivation-independent growth arrest as induced by Gas1.

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7 January 2021

The polyproline region of p53 is required to activate apoptosis but not growth arrest.

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7 January 2021

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

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7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

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7 January 2021

Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding

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7 January 2021

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7 January 2021

ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase.

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7 January 2021

Identification of a novel p53 functional domain that is necessary for efficient growth suppression

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7 January 2021

The XPB and XPD DNA helicases are components of the p53-mediated apoptosis pathway

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7 January 2021

p53 domains: identification and characterization of two autonomous DNA-binding regions.

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7 January 2021

Structure-based rescue of common tumor-derived p53 mutants

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1202841

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10467417%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

12 December 2019

1001875690

0 references

Fatcat ID

release_pz34ruw6h5h4bdnmhvyzikgxwe

0 references

1 reference