(Q78758452)

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Analysis of neurons created from wild-type and Alzheimer's mutation knock-in embryonic stem cells by a highly efficient differentiation protocol

scientific article published on 01 September 2003

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:13679420%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

Analysis of neurons created from wild-type and Alzheimer's mutation knock-in embryonic stem cells by a highly efficient differentiation protocol (English)

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Europe PubMed Central

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16 December 2019

Masaaki Matsuoka

7

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Masaaki Matsuoka

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16 December 2019

author name string

Yoichiro Abe

1

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16 December 2019

Keisuke Kouyama

2

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16 December 2019

Taisuke Tomita

3

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16 December 2019

Yusuke Tomita

4

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16 December 2019

Norimitsu Ban

5

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16 December 2019

Mikiro Nawa

6

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16 December 2019

Takako Niikura

8

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16 December 2019

Sadakazu Aiso

9

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16 December 2019

Yoshiko Kita

10

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16 December 2019

Takeshi Iwatsubo

11

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16 December 2019

Ikuo Nishimoto

12

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16 December 2019

publication date

1 September 2003

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16 December 2019

Journal of Neuroscience

1 reference

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16 December 2019

23

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16 December 2019

24

1 reference

Europe PubMed Central

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16 December 2019

8513-8525

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:13679420%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

Genes and susceptible loci of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurons derived in vitro from ES cells express homeoproteins characteristic of motoneurons and interneurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lineage-restricted neural precursors can be isolated from both the mouse neural tube and cultured ES cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel Leu723Pro amyloid precursor protein mutation increases amyloid beta42(43) peptide levels and induces apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple mechanisms underlie neurotoxicity by different types of Alzheimer's disease mutations of amyloid precursor protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal apoptosis by apolipoprotein E4 through low-density lipoprotein receptor-related protein and heterotrimeric GTPases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibody-regulated neurotoxic function of cell-surface beta-amyloid precursor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of neuroprotection by a novel rescue factor humanin from Swedish mutant amyloid precursor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Aβ

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurodegenerative tauopathies

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Abeta protofibril formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-yield selection and extraction of two promoter-defined phenotypes of neural stem cells from the fetal human brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enrichment of neurons and neural precursors from human embryonic stem cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro differentiation of transplantable neural precursors from human embryonic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neural progenitors from human embryonic stem cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotoxic mechanisms by Alzheimer's disease-linked N141I mutant presenilin 2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotoxic mechanisms triggered by Alzheimer's disease-linked mutant M146L presenilin 1: involvement of NO synthase via a novel pertussis toxin target

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Directed differentiation of embryonic stem cells into motor neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Framing beta-amyloid

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primary structure of high molecular weight tau present in the peripheral nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning of a big tau microtubule-associated protein characteristic of the peripheral nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and differential expression of a novel alternative splice isoform of the beta A4 amyloid precursor protein (APP) mRNA in leukocytes and brain microglial cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel species-specific RNA related to alternatively spliced amyloid precursor protein mRNAs.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropathological stageing of Alzheimer-related changes

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel mRNA of the A4 amyloid precursor gene coding for a possibly secreted protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the Alzheimer amyloid precursor gene transcripts in the human brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperphosphorylation of tau in PHF

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro differentiation of embryonic stem cells into glial cells and functional neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Embryonic stem cells express neuronal properties in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel ES cell line, TT2, with high germline-differentiating potency

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta A4-amyloid protein precursor mRNA isoforms without exon 15 are ubiquitously expressed in rat tissues including brain, but not in neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differentiation of pluripotent embryonic stem cells into the neuronal lineage in vitro gives rise to mature inhibitory and excitatory neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A beta A4 amyloid precursor protein gene and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

G protein-mediated neuronal DNA fragmentation induced by familial Alzheimer's disease-associated mutants of APP.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of neuronal precursor cells and functional postmitotic neurons from embryonic stem cells in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid beta protein ending at the 42nd (or 43rd) residue

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation of purified neural precursors from embryonic stem cells by lineage selection

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Embryonic stem cell lines derived from human blastocysts

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Derivation of pluripotent stem cells from cultured human primordial germ cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/13679420

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.23-24-08513.2003

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:13679420%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:13679420%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:13679420%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

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