(Q79294101)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14617576%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

title

Insulin-like growth factor (IGF)-I/IGF-binding protein-3 complex: therapeutic efficacy and mechanism of protection against type 1 diabetes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14617576%20AND%20SRC:MED&resulttype=core&format=json

https://api.crossref.org/works/10.1210/EN.2003-1274

21 December 2019

Insulin-Like Growth Factor (IGF)-I/IGF-Binding Protein-3 Complex: Therapeutic Efficacy and Mechanism of Protection against Type 1 Diabetes (English)

1 reference

2 April 2024

1 reference

1 reference

https://api.crossref.org/works/10.1210/EN.2003-1274

2 April 2024

author name string

Wei Chen

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14617576%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Qing-Sheng Mi

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14617576%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Marsha Grattan

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14617576%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Peter Zucker

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14617576%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Konstantin V. Salojin

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14617576

2 April 2024

T. Craig Meagher

5

1 reference

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2 April 2024

Terry L. Delovitch

7

1 reference

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2 April 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14617576

2 April 2024

publication date

14 November 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14617576%20AND%20SRC:MED&resulttype=core&format=json

full work available at URL

21 December 2019

published in

Endocrinology

1 reference

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21 December 2019

volume

145

1 reference

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21 December 2019

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14617576%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

page(s)

627-638

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14617576%20AND%20SRC:MED&resulttype=core&format=json

The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD.

21 December 2019

cites work

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Apoptosis and beta-cell destruction in pancreatic islets of NOD mice with spontaneous and cyclophosphamide-accelerated diabetes

2 April 2024

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Apoptosis is the mode of beta-cell death responsible for the development of IDDM in the nonobese diabetic (NOD) mouse

2 April 2024

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Beta cell destruction in the development of autoimmune diabetes in the non-obese diabetic (NOD) mouse

2 April 2024

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IFN-gamma/TNF-alpha synergism as the final effector in autoimmune diabetes: a key role for STAT1/IFN regulatory factor-1 pathway in pancreatic beta cell death

2 April 2024

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IFN gamma/TNF alpha synergism in MHC class II induction: effect of nicotinamide on MHC class II expression but not on islet-cell apoptosis

2 April 2024

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DNA fragmentation is an early event in cytokine-induced islet beta-cell destruction

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Tumor necrosis factor-alpha-activated cell death pathways in NIT-1 insulinoma cells and primary pancreatic beta cells

2 April 2024

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Transfection of human pancreatic islets with an anti-apoptotic gene (bcl-2) protects beta-cells from cytokine-induced destruction

2 April 2024

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cFLIP protein prevents tumor necrosis factor-alpha-mediated induction of caspase-8-dependent apoptosis in insulin-secreting betaTc-Tet cells

2 April 2024

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Insulin-like growth factors prevent cytokine-mediated cell death in isolated islets of Langerhans from pre-diabetic non-obese diabetic mice.

2 April 2024

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Growth factor protection against cytokine-induced apoptosis in neonatal rat islets of Langerhans: role of Fas

2 April 2024

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Insulin-like growth factor I reverses interleukin-1beta inhibition of insulin secretion, induction of nitric oxide synthase and cytokine-mediated apoptosis in rat islets of Langerhans

2 April 2024

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Inhibitory effect of IGF-I on type 2 nitric oxide synthase expression in Ins-1 cells and protection against activation-dependent apoptosis: involvement of phosphatidylinositol 3-kinase.

2 April 2024

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Prevention of beta cell dysfunction and apoptosis activation in human islets by adenoviral gene transfer of the insulin-like growth factor I.

2 April 2024

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Insulin-like growth factor-1 (IGF-1) protects NOD mice from insulitis and diabetes

2 April 2024

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Insulin-like growth factors (IGFs) and IGF-I treatment in the adolescent with insulin-dependent diabetes mellitus.

2 April 2024

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The effects of subcutaneous insulin-like growth factor-I infusion in insulin-dependent diabetes mellitus.

2 April 2024

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Pharmacokinetics and bioavailability of rhIGF-I/IGFBP-3 in the rat and monkey

2 April 2024

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Regulation of experimental autoimmune encephalomyelitis with insulin-like growth factor (IGF-1) and IGF-1/IGF-binding protein-3 complex (IGF-1/IGFBP3).

2 April 2024

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The combination of insulin-like growth factor I and insulin-like growth factor-binding protein-3 reduces insulin requirements in insulin-dependent type 1 diabetes: evidence for in vivo biological activity.

2 April 2024

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Muscle protein catabolism after severe burn: effects of IGF-1/IGFBP-3 treatment

2 April 2024

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27

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Glucose turnover and insulin sensitivity in rats with pancreatic islet transplants

2 April 2024

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Evidence that a peptide spanning the B-C junction of proinsulin is an early Autoantigen epitope in the pathogenesis of type 1 diabetes

2 April 2024

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Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice

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Differential expression of CC chemokines and the CCR5 receptor in the pancreas is associated with progression to type I diabetes.

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Early assessment of apoptosis in isolated islets of Langerhans

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Cellular actions of the insulin-like growth factor binding proteins

2 April 2024

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Cytokines induce apoptosis in beta-cells isolated from mice lacking the inducible isoform of nitric oxide synthase (iNOS-/-).

2 April 2024

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2 April 2024

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2 April 2024

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2 April 2024

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Transgenic overexpression of human Bcl-2 in islet β cells inhibits apoptosis but does not prevent autoimmune destruction

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2 April 2024

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2 April 2024

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2 April 2024

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2 April 2024

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2 April 2024

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2 April 2024

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Enhanced insulin-like growth factor I gene expression in regenerating rat pancreas

2 April 2024

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Beta cell expression of IGF-I leads to recovery from type 1 diabetes.

2 April 2024

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2 April 2024

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2 April 2024

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rhIGF-I/IGFBP-3 complex, but not free rhIGF-I, supports muscle protein biosynthesis in rats during semistarvation

2 April 2024

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Activation of IRS-2-mediated signal transduction by IGF-1, but not TGF-alpha or EGF, augments pancreatic beta-cell proliferation

2 April 2024

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Suppressor of cytokine signaling (SOCS)-3 protein interacts with the insulin-like growth factor-I receptor

2 April 2024

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Interaction of human suppressor of cytokine signaling (SOCS)-2 with the insulin-like growth factor-I receptor

2 April 2024

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Insulinlike growth factor I plus insulinlike growth factor binding protein 3 attenuates the proinflammatory acute phase response in severely burned children.

2 April 2024

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2 April 2024

Identifiers

DOI

10.1210/EN.2003-1274

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14617576%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference