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Spongistatin 1: a new chemosensitizing marine compound that degrades XIAP
scientific article published on 12 June 2008
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18548102
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18548102%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
title
Spongistatin 1: a new chemosensitizing marine compound that degrades XIAP
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18548102
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18548102%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
author
Irmela Jeremias
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18548102
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18548102%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
author name string
L Schyschka
series ordinal
1
1 reference
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Europe PubMed Central
PubMed publication ID
18548102
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18548102%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
A Rudy
series ordinal
2
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Europe PubMed Central
PubMed publication ID
18548102
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18548102%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
N Barth
series ordinal
4
1 reference
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Europe PubMed Central
PubMed publication ID
18548102
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18548102%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
G R Pettit
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18548102
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18548102%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
A M Vollmar
series ordinal
6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18548102
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18548102%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
publication date
12 June 2008
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18548102
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18548102%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
published in
Leukemia
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PubMed publication ID
18548102
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18548102%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
volume
22
1 reference
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Europe PubMed Central
PubMed publication ID
18548102
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18548102%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
issue
9
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Europe PubMed Central
PubMed publication ID
18548102
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18548102%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
page(s)
1737-1745
1 reference
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Europe PubMed Central
PubMed publication ID
18548102
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18548102%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
exact match
https://scigraph.springernature.com/pub.10.1038/leu.2008.146
0 references
cites work
The stereocontrolled total synthesis of altohyrtin A/spongistatin 1: fragment couplings, completion of the synthesis, analogue generation and biological evaluation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of apoptosis induced by marine natural products in non small cell lung cancer A549 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The CD95(APO-1/Fas) DISC and beyond
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Death and anti-death: tumour resistance to apoptosis
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FLEU.2008.146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dysregulation of apoptosis genes in hematopoietic malignancies.
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FLEU.2008.146
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7 January 2021
based on heuristic
inferred from DOI database lookup
Validating survivin as a cancer therapeutic target
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The inhibitors of apoptosis (IAPs) and their emerging role in cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IAP proteins: blocking the road to death's door
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A comprehensive search for DNA amplification in lung cancer identifies inhibitors of apoptosis cIAP1 and cIAP2 as candidate oncogenes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A small molecule Smac-mimic compound induces apoptosis and sensitizes TRAIL- and etoposide-induced apoptosis in breast cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Translational upregulation of X-linked inhibitor of apoptosis (XIAP) increases resistance to radiation induced cell death.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
APO-1 (CD95)-dependent and -independent antigen receptor-induced apoptosis in human T and B cell lines.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Staurosporine and conventional anticancer drugs induce overlapping, yet distinct pathways of apoptosis and caspase activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Upstream regulatory role for XIAP in receptor-mediated apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
1-Methyl-4-phenylpyridinium induces autocrine excitotoxicity, protease activation, and neuronal apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modulation of apoptosis signaling for cancer therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of XIAP-mediated inhibition of caspase-9
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Calpain-mediated X-linked inhibitor of apoptosis degradation in neutrophil apoptosis and its impairment in chronic neutrophilic leukemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of XIAP protein expression by RNAi and antisense approaches sensitizes cancer cells to functionally diverse chemotherapeutics
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Application of XIAP antisense to cancer and other proliferative disorders: development of AEG35156/ GEM640
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeting XIAP for the treatment of malignancy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sensitization of pancreatic carcinoma cells for γ-irradiation-induced apoptosis by XIAP inhibition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Discovery of potent antagonists of the antiapoptotic protein XIAP for the treatment of cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High expression levels of x-linked inhibitor of apoptosis protein and survivin correlate with poor overall survival in childhood de novo acute myeloid leukemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.146
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/LEU.2008.146
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18548102
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18548102%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
Dimensions Publication ID
1020647127
0 references
PubMed publication ID
18548102
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18548102
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18548102%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 January 2020
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