(Q81589359)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17998065%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

title

Hypoxia-inducible factor 1 inhibitors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17998065%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

author name string

Giovanni Melillo

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17998065%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

publication date

1 January 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17998065%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

number of pages

18

1 reference

inferred from page(s)

published in

Methods in Enzymology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17998065%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

volume

435

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17998065%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

page(s)

385-402

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17998065%20AND%20SRC:MED&resulttype=core&format=json

Identification of novel small molecule inhibitors of hypoxia-inducible factor-1 that differentially block hypoxia-inducible factor-1 activity and hypoxia-inducible factor-1alpha induction in response to hypoxic stress and growth factors

10 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935020-9

7 January 2021

Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935020-9

7 January 2021

Transcription factors as targets for cancer therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935020-9

7 January 2021

Structural basis for PAS domain heterodimerization in the basic helix-loop-helix-PAS transcription factor hypoxia-inducible factor

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935020-9

7 January 2021

HIF-1 as a target for drug development

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935020-9

7 January 2021

Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935020-9

7 January 2021

Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935020-9

7 January 2021

Novel thioredoxin inhibitors paradoxically increase hypoxia-inducible factor-alpha expression but decrease functional transcriptional activity, DNA binding, and degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935020-9

7 January 2021

Proteasomal inhibition attenuates transcriptional activity of hypoxia-inducible factor 1 (HIF-1) via specific effect on the HIF-1alpha C-terminal activation domain

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935020-9

7 January 2021

Identification of a new natural camptothecin analogue in targeted screening for HIF-1alpha inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935020-9

7 January 2021

Echinomycin, a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935020-9

7 January 2021

Histone deacetylase inhibitors induce VHL and ubiquitin-independent proteasomal degradation of hypoxia-inducible factor 1alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935020-9

7 January 2021

Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935020-9

7 January 2021

2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935020-9

7 January 2021

H2AX may function as an anchor to hold broken chromosomal DNA ends in close proximity

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935020-9

7 January 2021

Inhibiting hypoxia-inducible factor 1 for cancer therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935020-9

7 January 2021

Improved nuclear localization of DNA-binding polyamides

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935020-9

7 January 2021

Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935020-9

7 January 2021

Targeting the PAS-A domain of HIF-1alpha for development of small molecule inhibitors of HIF-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935020-9

7 January 2021

Class II histone deacetylases are associated with VHL-independent regulation of hypoxia-inducible factor 1 alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935020-9

7 January 2021

Topoisomerase I-mediated inhibition of hypoxia-inducible factor 1: mechanism and therapeutic implications

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935020-9

7 January 2021

Schedule-dependent inhibition of hypoxia-inducible factor-1alpha protein accumulation, angiogenesis, and tumor growth by topotecan in U251-HRE glioblastoma xenografts

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935020-9

7 January 2021

Targeting HIF-1 for cancer therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935020-9

7 January 2021

Application of high-throughput, molecular-targeted screening to anticancer drug discovery

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935020-9

7 January 2021

Echinomycin Binding Sites on DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935020-9

7 January 2021

General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935020-9

7 January 2021

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935020-9

7 January 2021

Functions of the Per/ARNT/Sim domains of the hypoxia-inducible factor

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935020-9

7 January 2021

YC-1: a potential anticancer drug targeting hypoxia-inducible factor 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2807%2935020-9

7 January 2021

10.1016/S0076-6879(07)35020-9

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17998065%20AND%20SRC:MED&resulttype=core&format=json

10 January 2020

1 reference