(Q84846824)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21873997%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

Epigenetics: Targeting leukemia on the DOT (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21873997%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

Jon Travers

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21873997%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Julian Blagg

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21873997%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Paul Workman

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21873997%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

publication date

28 August 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21873997%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

published in

Nature Chemical Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21873997%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21873997%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21873997%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

page(s)

663-665

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21873997%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nchembio.661

11 February 2020

exact match

0 references

cites work

DNMT3A Mutations in Acute Myeloid Leukemia

1 reference

12 December 2020

Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia

1 reference

12 December 2020

Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer

1 reference

12 December 2020

TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis

1 reference

12 December 2020

Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin

1 reference

12 December 2020

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

1 reference

12 December 2020

Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor.

1 reference

12 December 2020

Protein methyltransferases as a target class for drug discovery

1 reference

12 December 2020

Structure of the catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase

1 reference

12 December 2020

Cancer epigenetics reaches mainstream oncology

1 reference

12 December 2020

Probing the probes: fitness factors for small molecule tools

1 reference

12 December 2020

MLL translocations, histone modifications and leukaemia stem-cell development

1 reference

12 December 2020

MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCHEMBIO.661

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21873997%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference