(Q85645987)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25263447%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

title

p53 protein aggregation promotes platinum resistance in ovarian cancer (English)

1 reference

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20 February 2020

1 reference

1 reference

Y Yang-Hartwich

1

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20 February 2020

M G Soteras

2

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20 February 2020

Z P Lin

3

1 reference

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20 February 2020

J Holmberg

4

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20 February 2020

N Sumi

5

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20 February 2020

V Craveiro

6

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20 February 2020

M Liang

7

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20 February 2020

E Romanoff

8

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20 February 2020

J Bingham

9

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20 February 2020

F Garofalo

10

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20 February 2020

A Alvero

11

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20 February 2020

G Mor

12

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20 February 2020

publication date

29 September 2014

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20 February 2020

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20 February 2020

volume

34

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20 February 2020

issue

27

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20 February 2020

page(s)

3605-3616

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https://scigraph.springernature.com/pub.10.1038/onc.2014.296

20 February 2020

exact match

0 references

cites work

Clinical practice. Screening for ovarian cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Integrated genomic analyses of ovarian carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Mutant p53: one name, many proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

High-level expression of wild-type p53 in melanoma cells is frequently associated with inactivity in p53 reporter gene assays

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Poor survival with wild-type TP53 ovarian cancer?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Expanding the prion concept to cancer biology: dominant-negative effect of aggregates of mutant p53 tumour suppressor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Gain of function of mutant p53 by coaggregation with multiple tumor suppressors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Mutant p53 aggregates into prion-like amyloid oligomers and fibrils: implications for cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Co-localization of mutant p53 and amyloid-like protein aggregates in breast tumors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Unfolding, aggregation, and amyloid formation by the tetramerization domain from mutant p53 associated with lung cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Fibrillar aggregates of the tumor suppressor p53 core domain

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

The (1-63) region of the p53 transactivation domain aggregates in vitro into cytotoxic amyloid assemblies.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Structure, function, and aggregation of the zinc-free form of the p53 DNA binding domain

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Reversible aggregation plays a crucial role on the folding landscape of p53 core domain

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

p53 Aggregates penetrate cells and induce the co-aggregation of intracellular p53.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Dual role of p53 amyloid formation in cancer; loss of function and gain of toxicity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Prospective identification of tumorigenic breast cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

CD133, a novel marker for human prostatic epithelial stem cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Pathogenesis of ovarian cancer: clues from selected overexpressed genes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Pluripotency factors Lin28 and Oct4 identify a sub-population of stem cell-like cells in ovarian cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Ovarian cancer stem cell-like side populations are enriched following chemotherapy and overexpress EZH2.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Stem cell pathways contribute to clinical chemoresistance in ovarian cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Molecular phenotyping of human ovarian cancer stem cells unravels the mechanisms for repair and chemoresistance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Stem-like ovarian cancer cells can serve as tumor vascular progenitors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Regulation of IKKbeta by miR-199a affects NF-kappaB activity in ovarian cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Phenotypic modifications in ovarian cancer stem cells following Paclitaxel treatment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Protein aggregation diseases: pathogenicity and therapeutic perspectives

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Nucleolar Arf sequesters Mdm2 and activates p53

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

MDM2 and human malignancies: expression, clinical pathology, prognostic markers, and implications for chemotherapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Molecular mechanism of Thioflavin-T binding to amyloid fibrils

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Correlations of partial and extensive methylation at the p14(ARF) locus with reduced mRNA expression in colorectal cancer cell lines and clinicopathological features in primary tumors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

The ubiquitin proteolytic system: from a vague idea, through basic mechanisms, and onto human diseases and drug targeting

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2014.296

Autophagy gone awry in neurodegenerative diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Correlation of metabolic stability and altered quaternary structure of oncoprotein p53 with cell transformation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Kinetic mechanism of p53 oncogenic mutant aggregation and its inhibition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Prion-like aggregation of mutant p53 in cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Inhibition of MDM2 by hsp90 contributes to mutant p53 stabilization

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Production and purification of lentiviral vectors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Phenoxodiol – an isoflavone analog – induces apoptosis in chemoresistant ovarian cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Conformation-dependent anti-amyloid oligomer antibodies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

cDNA sequencing improves the detection of P53 missense mutations in colorectal cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Characterizing transcription factor binding sites using formaldehyde crosslinking and immunoprecipitation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Proteomics identifies multipotent and low oncogenic risk stem cells of the spleen

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.296

Promoter methylation of INK4a/ARF as detected in bile-significance for the differential diagnosis in biliary disease

31 March 2020

1 reference

12 December 2020

Frequently elevated content of immunochemically defined wild-type p53 protein in colorectal adenomas

1 reference

12 December 2020

Two-dimensional difference gel electrophoresis

1 reference

12 December 2020

Wild-type and mutant forms of p53 activate human topoisomerase I: a possible mechanism for gain of function in mutants.

1 reference

12 December 2020

MDM2, an introduction.

1 reference

12 December 2020

Identifiers

DOI

10.1038/ONC.2014.296

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25263447%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

20 February 2020

0 references

1 reference