(Q88208247)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24990498%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

title

Protease-activated receptor signalling by coagulation proteases in endothelial cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24990498%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

author name string

Alireza R Rezaie

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24990498%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

publication date

3 July 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24990498%20AND%20SRC:MED&resulttype=core&format=json

Thrombosis and Haemostasis

21 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24990498%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

volume

112

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24990498%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24990498%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

page(s)

876-882

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24990498%20AND%20SRC:MED&resulttype=core&format=json

Protease activated receptor 1 (PAR-1) activation by thrombin is protective in human pulmonary artery endothelial cells if endothelial protein C receptor is occupied by its natural ligand.

21 March 2020

cites work

1 reference

12 December 2020

Protective effects of activated protein C in sepsis

1 reference

12 December 2020

Activated protein C ligation of ApoER2 (LRP8) causes Dab1-dependent signaling in U937 cells

1 reference

12 December 2020

Thrombin inhibits nuclear factor kappaB and RhoA pathways in cytokine-stimulated vascular endothelial cells when EPCR is occupied by protein C.

1 reference

12 December 2020

Activated protein C: a promising drug with multiple effects?

1 reference

12 December 2020

The protein C pathway and pathologic processes

1 reference

12 December 2020

Activated protein C utilizes the angiopoietin/Tie2 axis to promote endothelial barrier function.

1 reference

12 December 2020

Factor VIIa interaction with endothelial cells and endothelial cell protein C receptor

1 reference

12 December 2020

The efficacy of activated protein C in murine endotoxemia is dependent on integrin CD11b

1 reference

12 December 2020

Coagulation factor Xa induces an inflammatory signalling by activation of protease-activated receptors in human atrial tissue

1 reference

12 December 2020

Protease-activated receptor 1 (PAR1) and PAR4 heterodimers are required for PAR1-enhanced cleavage of PAR4 by α-thrombin

1 reference

12 December 2020

Activation of blood coagulation in cancer: implications for tumour progression

1 reference

12 December 2020

Adenosine regulates the proinflammatory signaling function of thrombin in endothelial cells

1 reference

12 December 2020

Thrombin upregulates the angiopoietin-Tie2 Axis: endothelial protein C receptor occupancy prevents the thrombin mobilization of angiopoietin 2 and P-selectin from Weibel-Palade bodies

1 reference

12 December 2020

Factor X/Xa Elicits Protective Signaling Responses in Endothelial Cells Directly via PAR-2 and Indirectly via Endothelial Protein C Receptor-dependent Recruitment of PAR-1

1 reference

12 December 2020

Factor VIIa bound to endothelial cell protein C receptor activates protease activated receptor-1 and mediates cell signaling and barrier protection

1 reference

12 December 2020

Protease-activated receptors and myocardial infarction

1 reference

12 December 2020

The occupancy of endothelial protein C receptor by its ligand modulates the par-1 dependent signaling specificity of coagulation proteases

1 reference

12 December 2020

Multiple receptor-mediated functions of activated protein C.

1 reference

12 December 2020

Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signaling

1 reference

12 December 2020

Activated protein C inhibits high mobility group box 1 signaling in endothelial cells

1 reference

12 December 2020

Protein C anticoagulant system--anti-inflammatory effects

1 reference

12 December 2020

Drug for severe sepsis is withdrawn from market, fails to reduce mortality

1 reference

12 December 2020

Activated protein C promotes protease-activated receptor-1 cytoprotective signaling through β-arrestin and dishevelled-2 scaffolds

1 reference

12 December 2020

Determinants of the specificity of protease-activated receptors 1 and 2 signaling by factor Xa and thrombin

1 reference

12 December 2020

Identification of exosite residues of factor Xa involved in recognition of PAR-2 on endothelial cells

1 reference

12 December 2020

Activation of endothelial cell protease activated receptor 1 by the protein C pathway

1 reference

12 December 2020

Specificity of coagulation factor signaling

1 reference

12 December 2020

Activated protein C prevents neuronal apoptosis via protease activated receptors 1 and 3

1 reference

12 December 2020

Protease-activated receptors: contribution to physiology and disease

1 reference

12 December 2020

Protease-activated receptor 2-dependent phosphorylation of the tissue factor cytoplasmic domain

1 reference

12 December 2020

Use of endothelium cultured on microcarriers as a model for the microcirculation

1 reference

12 December 2020

Internalization and recycling of activated thrombin receptors

1 reference

12 December 2020

Glycosaminoglycan contributions to both protein C activation and thrombin inhibition involve a common arginine-rich site in thrombin that includes residues arginine 93, 97, and 101

1 reference

12 December 2020

Identification, cloning, and regulation of a novel endothelial cell protein C/activated protein C receptor

1 reference

12 December 2020

Intracellular targeting and trafficking of thrombin receptors. A novel mechanism for resensitization of a G protein-coupled receptor

1 reference

12 December 2020

Activation-dependent exposure of the inter-EGF sequence Leu83-Leu88 in factor Xa mediates ligand binding to effector cell protease receptor-1.

1 reference

12 December 2020

Protease-activated receptor-1 cleaved at R46 mediates cytoprotective effects.

1 reference

12 December 2020

Effectiveness and safety of drotrecogin alfa (activated) for severe sepsis: a meta-analysis and metaregression

1 reference

12 December 2020

Biased agonism of protease-activated receptor 1 by activated protein C caused by noncanonical cleavage at Arg46.

1 reference

12 December 2020

Activated protein C ameliorates diabetic nephropathy by epigenetically inhibiting the redox enzyme p66Shc

1 reference

12 December 2020

Mechanisms of anticoagulant and cytoprotective actions of the protein C pathway

1 reference

12 December 2020

Novel mechanisms for activated protein C cytoprotective activities involving noncanonical activation of protease-activated receptor 3.

1 reference

12 December 2020

Efficacy and safety of recombinant human activated protein C for severe sepsis

1 reference

12 December 2020

Gene expression profile of antithrombotic protein c defines new mechanisms modulating inflammation and apoptosis

1 reference

12 December 2020

Mechanistic coupling of protease signaling and initiation of coagulation by tissue factor

1 reference

12 December 2020

The interaction between the endothelial cell protein C receptor and protein C is dictated by the gamma-carboxyglutamic acid domain of protein C.

1 reference

12 December 2020

Cloning and characterization of human protease-activated receptor 4

1 reference

12 December 2020

Thrombin-activated human endothelial cells support monocyte adhesion in vitro following expression of intercellular adhesion molecule-1 (ICAM-1; CD54) and vascular cell adhesion molecule-1 (VCAM-1; CD106).

1 reference

12 December 2020

Factor Xa induces cytokine production and expression of adhesion molecules by human umbilical vein endothelial cells

1 reference

12 December 2020

Tissue factor cytoplasmic domain stimulates migration by activation of the GTPase Rac1 and the mitogen-activated protein kinase p38.

1 reference

12 December 2020

PAR1 cleavage and signaling in response to activated protein C and thrombin.

1 reference

12 December 2020

Endothelial barrier protection by activated protein C through PAR1-dependent sphingosine 1-phosphate receptor-1 crossactivation

1 reference

12 December 2020

Activated protein C mediates novel lung endothelial barrier enhancement: role of sphingosine 1-phosphate receptor transactivation

1 reference

12 December 2020

Functional selectivity of G protein signaling by agonist peptides and thrombin for the protease-activated receptor-1.

1 reference

12 December 2020

Protease-activated receptors in hemostasis, thrombosis and vascular biology

1 reference

12 December 2020

1 reference

12 December 2020

Protease-activated receptors-1 and -2 can mediate endothelial barrier protection: role in factor Xa signaling

1 reference

12 December 2020

Protective signaling by activated protein C is mechanistically linked to protein C activation on endothelial cells.

1 reference

12 December 2020

Factor Xa and thrombin evoke additive calcium and proinflammatory responses in endothelial cells subjected to coagulation

1 reference

12 December 2020

Protease-activated receptors in cardiovascular diseases

1 reference

12 December 2020

New roles for beta-arrestins in cell signaling: not just for seven-transmembrane receptors

1 reference

12 December 2020

Receptors of the protein C activation and activated protein C signaling pathways are colocalized in lipid rafts of endothelial cells

1 reference

12 December 2020

Protease-activated receptor-3 (PAR3) regulates PAR1 signaling by receptor dimerization

1 reference

12 December 2020

The cytoprotective protein C pathway

1 reference

12 December 2020

Cytokine upregulation of proteinase-activated-receptors 2 and 4 expression mediated by p38 MAP kinase and inhibitory kappa B kinase beta in human endothelial cells

1 reference

12 December 2020

Endothelial cell protein C receptor acts as a cellular receptor for factor VIIa on endothelium

1 reference

12 December 2020

Modulation of tissue factor-factor VIIa signaling by lipid rafts and caveolae

1 reference

12 December 2020

Regulation of macrophage procoagulant responses by the tissue factor cytoplasmic domain in endotoxemia.

1 reference

12 December 2020

Interaction of thrombin with PAR1 and PAR4 at the thrombin cleavage site

1 reference

12 December 2020

Protease-activated receptor-4 inhibition protects from multiorgan failure in a murine model of systemic inflammation

1 reference

12 December 2020

The ligand occupancy of endothelial protein C receptor switches the protease-activated receptor 1-dependent signaling specificity of thrombin from a permeability-enhancing to a barrier-protective response in endothelial cells

1 reference

12 December 2020

Inhibition of tissue factor signaling suppresses tumor growth

1 reference

12 December 2020

Activated protein C-cleaved protease activated receptor-1 is retained on the endothelial cell surface even in the presence of thrombin

1 reference

12 December 2020

Factor Xa binding to annexin 2 mediates signal transduction via protease-activated receptor 1.

1 reference

12 December 2020

Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation

1 reference

12 December 2020

Lipid raft localization regulates the cleavage specificity of protease activated receptor 1 in endothelial cells.

1 reference

12 December 2020

Identifiers

DOI

10.1160/TH14-02-0167

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24990498%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24990498%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

PubMed publication ID

24990498

1 reference