(Q89055887)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29887596%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

title

YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for glioblastoma tumorigenicity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29887596%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

1 reference

10

1 reference

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30 March 2020

Olga Meiri Chaim

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29887596%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

9

Anjana Rao

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29887596%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

author name string

Olivia M Yu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29887596%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Jorge A Benitez

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29887596%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Steven W Plouffe

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29887596%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Daniel Ryback

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29887596%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Andrea Klein

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29887596%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Jeff Smith

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29887596%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Jason Greenbaum

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29887596%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Benjamin Delatte

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29887596%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Frank B Furnari

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29887596%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Shigeki Miyamoto

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29887596%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

Joan Heller Brown

14

1 reference

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30 March 2020

publication date

11 June 2018

1 reference

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30 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29887596%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

volume

37

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29887596%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

issue

41

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29887596%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

page(s)

5492-5507

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29887596%20AND%20SRC:MED&resulttype=core&format=json

Leukemia-associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G(12) family to Rho

30 March 2020

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7 January 2021

Leukemia-associated Rho guanine nucleotide exchange factor, a Dbl family protein found mutated in leukemia, causes transformation by activation of RhoA

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7 January 2021

RHO-GTPases and cancer

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7 January 2021

A mutant alpha subunit of G12 potentiates the eicosanoid pathway and is highly oncogenic in NIH 3T3 cells

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7 January 2021

Implications of Rho GTPase Signaling in Glioma Cell Invasion and Tumor Progression

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7 January 2021

Role of G12 proteins in oncogenesis and metastasis

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7 January 2021

Coupling of the thrombin receptor to G12 may account for selective effects of thrombin on gene expression and DNA synthesis in 1321N1 astrocytoma cells

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7 January 2021

Thrombin receptor and RhoA mediate cell proliferation through integrins and cysteine-rich protein 61.

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7 January 2021

G Protein-Coupled Receptor and RhoA-Stimulated Transcriptional Responses: Links to Inflammation, Differentiation, and Cell Proliferation

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7 January 2021

A role for Rho in Ras transformation

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7 January 2021

Hippo-independent activation of YAP by the GNAQ uveal melanoma oncogene through a trio-regulated rho GTPase signaling circuitry.

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7 January 2021

Rho GTPase activity modulates Wnt3a/beta-catenin signaling

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7 January 2021

Alternative Wnt Signaling Activates YAP/TAZ.

1 reference

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7 January 2021

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

1 reference

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7 January 2021

RhoA effector mutants reveal distinct effector pathways for cytoskeletal reorganization, SRF activation and transformation.

1 reference

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7 January 2021

Megakaryoblastic leukemia 1, a potent transcriptional coactivator for serum response factor (SRF), is required for serum induction of SRF target genes

1 reference

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7 January 2021

Actin dynamics control SRF activity by regulation of its coactivator MAL

1 reference

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7 January 2021

Myocardin/MKL family of SRF coactivators: key regulators of immediate early and muscle specific gene expression

1 reference

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7 January 2021

RPEL motifs link the serum response factor cofactor MAL but not myocardin to Rho signaling via actin binding

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7 January 2021

Thromboxane A2 Activates YAP/TAZ Protein to Induce Vascular Smooth Muscle Cell Proliferation and Migration

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7 January 2021

Regulation of the Hippo-YAP pathway by protease-activated receptors (PARs).

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7 January 2021

Mutant Gq/11 promote uveal melanoma tumorigenesis by activating YAP

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7 January 2021

Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling

1 reference

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7 January 2021

A mechanical checkpoint controls multicellular growth through YAP/TAZ regulation by actin-processing factors.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

Role of YAP/TAZ in mechanotransduction

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

TEAD mediates YAP-dependent gene induction and growth control

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

Both TEAD-binding and WW domains are required for the growth stimulation and oncogenic transformation activity of yes-associated protein

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

Long term culture of normal and neoplastic human glia.

1 reference

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7 January 2021

Cyclic stretching of soft substrates induces spreading and growth

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7 January 2021

The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules

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https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

The somatic genomic landscape of glioblastoma

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7 January 2021

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

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7 January 2021

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

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https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

An Essential Role for Rho, Rac, and Cdc42 GTPases in Cell Cycle Progression Through G 1

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

The thrombin receptor, PAR-1, causes transformation by activation of Rho-mediated signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

Sphingosine kinase 1 is up-regulated during hypoxia in U87MG glioma cells. Role of hypoxia-inducible factors 1 and 2.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

Expression of S1P metabolizing enzymes and receptors correlate with survival time and regulate cell migration in glioblastoma multiforme

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

Targeting sphingosine kinase 1 inhibits Akt signaling, induces apoptosis, and suppresses growth of human glioblastoma cells and xenografts

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

The role of thrombin in gliomas.

1 reference

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7 January 2021

Thrombin induces tumor growth, metastasis, and angiogenesis: Evidence for a thrombin-regulated dormant tumor phenotype

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7 January 2021

Autotaxin is overexpressed in glioblastoma multiforme and contributes to cell motility of glioblastoma by converting lysophosphatidylcholine to lysophosphatidic acid

1 reference

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7 January 2021

Autotaxin and LPA receptor signaling in cancer

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7 January 2021

Identification of molecular characteristics correlated with glioblastoma sensitivity to EGFR kinase inhibition through use of an intracranial xenograft test panel

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7 January 2021

Use of an orthotopic xenograft model for assessing the effect of epidermal growth factor receptor amplification on glioblastoma radiation response.

1 reference

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7 January 2021

Patient tumor EGFR and PDGFRA gene amplifications retained in an invasive intracranial xenograft model of glioblastoma multiforme

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

Aberrant mesenchymal differentiation of glioma stem-like cells: implications for therapeutic targeting

1 reference

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7 January 2021

Epigenetic reprogramming in cancer

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7 January 2021

YAP/TAZ at the Roots of Cancer.

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7 January 2021

Rho-actin signaling to the MRTF coactivators dominates the immediate transcriptional response to serum in fibroblasts

1 reference

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7 January 2021

Heparin-binding epidermal growth factor-like growth factor stimulates mitogenic signaling and is highly expressed in human malignant gliomas

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

Validation of HB-EGF and amphiregulin as targets for human cancer therapy.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

An EGFR wild type-EGFRvIII-HB-EGF feed-forward loop regulates the activation of EGFRvIII.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

Expression of tissue factor correlates with grade of malignancy in human glioma.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

Tissue factor expression provokes escape from tumor dormancy and leads to genomic alterations

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

The contribution of tumor and host tissue factor expression to oncogene-driven gliomagenesis

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

Elevated YAP and its downstream targets CCN1 and CCN2 in basal cell carcinoma: impact on keratinocyte proliferation and stromal cell activation.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

Myc inhibition is effective against glioma and reveals a role for Myc in proficient mitosis.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

Cyr61 promotes growth of glioblastoma in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

Extracellular matrix protein CCN1 limits oncolytic efficacy in glioma

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

Levels of expression of CYR61 and CTGF are prognostic for tumor progression and survival of individuals with gliomas

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

A novel CYR61-triggered 'CYR61-alphavbeta3 integrin loop' regulates breast cancer cell survival and chemosensitivity through activation of ERK1/ERK2 MAPK signaling pathway.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

c-Myc is required for maintenance of glioma cancer stem cells

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

Disease implications of the Hippo/YAP pathway

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

YAP Regulates Actin Dynamics through ARHGAP29 and Promotes Metastasis

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

217 YAP Is Ready to Rac and Rho: Elucidation of a Novel YAP-Driven Network That Potentiates Brain Cancer Cell Dispersal and Confers Poor Survival in Patients

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

Tissue factor and cell signalling in cancer progression and thrombosis

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

Tissue factor in tumour progression

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

Astrocyte tissue factor controls CNS hemostasis and autoimmune inflammation

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

Heparin-binding epidermal growth factor-like growth factor promotes neuroblastoma differentiation

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

Discovery and saturation analysis of cancer genes across 21 tumour types

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

Genome engineering using the CRISPR-Cas9 system

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

Analyzing real-time PCR data by the comparative C(T) method

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

Metalloproteinases ADAM10 and ADAM17 Mediate Migration and Differentiation in Glioblastoma Sphere-Forming Cells

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

Cancer stem cells in glioblastoma

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0301-5

7 January 2021

Novel human oncogene lbc detected by transfection with distinct homology regions to signal transduction products

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29887596

12 December 2020

inferred from PubMed ID database lookup

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29887596

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/S41388-018-0301-5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29887596%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29887596%20AND%20SRC:MED&resulttype=core&format=json

30 March 2020

PubMed publication ID

29887596

1 reference