(Q89181535)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29930302%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

title

Regulation of chromatin and gene expression by metabolic enzymes and metabolites (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29930302%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29930302%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

author name string

Xinjian Li

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29930302%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Yugang Wang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29930302%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Shelley L Berger

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29930302%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

Zhimin Lu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29930302%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

publication date

1 September 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29930302%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Molecular Cell Biology

1 April 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29930302%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

volume

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29930302%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29930302%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

page(s)

563-578

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29930302%20AND%20SRC:MED&resulttype=core&format=json

Crystal structure of the nucleosome core particle at 2.8 A resolution

1 April 2020

cites work

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The language of covalent histone modifications

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7 January 2021

Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification

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7 January 2021

SnapShot: histone modifications

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Histone core modifications regulating nucleosome structure and dynamics

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7 January 2021

A decade of exploring the cancer epigenome - biological and translational implications

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7 January 2021

Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation

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7 January 2021

Multivalent engagement of chromatin modifications by linked binding modules

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7 January 2021

Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers

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7 January 2021

Cancer epigenetics: from mechanism to therapy

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7 January 2021

From neural development to cognition: unexpected roles for chromatin

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7 January 2021

Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma

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7 January 2021

Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape

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7 January 2021

Structural and functional coordination of DNA and histone methylation

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7 January 2021

The complex language of chromatin regulation during transcription

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7 January 2021

S-adenosylmethionine and its products

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7 January 2021

Histone Methylation Dynamics and Gene Regulation Occur through the Sensing of One-Carbon Metabolism

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7 January 2021

Methionine metabolism regulates maintenance and differentiation of human pluripotent stem cells.

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7 January 2021

Metabolism and epigenetics.

1 reference

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7 January 2021

Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development

1 reference

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7 January 2021

A Metabolic Function for Phospholipid and Histone Methylation.

1 reference

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7 January 2021

Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4

1 reference

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7 January 2021

Histone demethylation catalysed by LSD1 is a flavin-dependent oxidative process

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7 January 2021

The discovery of histone demethylases

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7 January 2021

Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells

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7 January 2021

Psat1-Dependent Fluctuations in α-Ketoglutarate Affect the Timing of ESC Differentiation.

1 reference

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7 January 2021

What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer

1 reference

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7 January 2021

Krebs cycle intermediates regulate DNA and histone methylation: epigenetic impact on the aging process

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Histone methylation: a dynamic mark in health, disease and inheritance

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Lysyl 5-hydroxylation, a novel histone modification, by Jumonji domain containing 6 (JMJD6)

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus

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7 January 2021

Spatiotemporal Control of Acetyl-CoA Metabolism in Chromatin Regulation.

1 reference

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7 January 2021

Acetyl-CoA induces cell growth and proliferation by promoting the acetylation of histones at growth genes.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Lysine propionylation and butyrylation are novel post-translational modifications in histones

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Lysine 2-hydroxyisobutyrylation is a widely distributed active histone mark

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Lysine succinylation and lysine malonylation in histones.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Metabolic regulation of gene expression through histone acylations

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Intracellular crotonyl-CoA stimulates transcription through p300-catalyzed histone crotonylation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Metabolic Regulation of Gene Expression by Histone Lysine β-Hydroxybutyrylation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Identification and characterization of propionylation at histone H3 lysine 23 in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Dynamic Competing Histone H4 K5K8 Acetylation and Butyrylation Are Hallmarks of Highly Active Gene Promoters

1 reference

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7 January 2021

Histone propionylation is a mark of active chromatin

1 reference

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7 January 2021

Fuel metabolism in starvation

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7 January 2021

Ketone bodies: a review of physiology, pathophysiology and application of monitoring to diabetes

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7 January 2021

Physiological roles of ketone bodies as substrates and signals in mammalian tissues

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7 January 2021

Protein O-GlcNAcylation: emerging mechanisms and functions

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7 January 2021

Nutrient regulation of gene expression by O-GlcNAcylation of chromatin

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7 January 2021

A critical perspective of the diverse roles of O-GlcNAc transferase in chromatin

1 reference

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7 January 2021

PARP goes transcription

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

PARPs and ADP-ribosylation: recent advances linking molecular functions to biological outcomes

1 reference

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7 January 2021

HPF1/C4orf27 Is a PARP-1-Interacting Protein that Regulates PARP-1 ADP-Ribosylation Activity

1 reference

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7 January 2021

Poly(ADP-ribosyl)ation of polynucleosomes causes relaxation of chromatin structure

1 reference

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7 January 2021

CDK2-dependent activation of PARP-1 is required for hormonal gene regulation in breast cancer cells.

1 reference

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7 January 2021

The role of PARP-1 and PARP-2 enzymes in metabolic regulation and disease

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Chemical genetic discovery of PARP targets reveals a role for PARP-1 in transcription elongation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

PARP-1 regulates chromatin structure and transcription through a KDM5B-dependent pathway

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Pyruvate kinase M2 at a glance

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Tissue-specific isoform switch and DNA hypomethylation of the pyruvate kinase PKM gene in human cancers.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

EGFR-induced and PKCε monoubiquitylation-dependent NF-κB activation upregulates PKM2 expression and promotes tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

EGF mutant receptor vIII as a molecular target in cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Prolyl isomerase Pin1 in cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

The SUMO-E3 ligase PIAS3 targets pyruvate kinase M2.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Mitogenic and oncogenic stimulation of K433 acetylation promotes PKM2 protein kinase activity and nuclear localization

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

JMJD5 regulates PKM2 nuclear translocation and reprograms HIF-1α-mediated glucose metabolism.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Lack of Evidence for PKM2 Protein Kinase Activity

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Serine and SAM Responsive Complex SESAME Regulates Histone Modification Crosstalk by Sensing Cellular Metabolism.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Regulation of SESAME-mediated H3T11 phosphorylation by glycolytic enzymes and metabolites

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Pyruvate kinase M2 regulates gene transcription by acting as a protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Cytosolic thyroid hormone-binding protein is a monomer of pyruvate kinase

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Control of glioma cell death and differentiation by PKM2-Oct4 interaction

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Nuclear pyruvate kinase M2 complex serves as a transcriptional coactivator of arylhydrocarbon receptor

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Lysine succinylation is a frequently occurring modification in prokaryotes and eukaryotes and extensively overlaps with acetylation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Identification of lysine succinylation as a new post-translational modification

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Local generation of fumarate promotes DNA repair through inhibition of histone H3 demethylation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Fumarase: a mitochondrial metabolic enzyme and a cytosolic/nuclear component of the DNA damage response

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

An antioxidant response phenotype shared between hereditary and sporadic type 2 papillary renal cell carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

O-GlcNAcylation of fumarase maintains tumour growth under glucose deficiency.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Fructose-1,6-bisphosphatase opposes renal carcinoma progression

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

S phase activation of the histone H2B promoter by OCA-S, a coactivator complex that contains GAPDH as a key component

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

IMP dehydrogenase: structure, mechanism, and inhibition

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Metabolic enzyme IMPDH is also a transcription factor regulated by cellular state

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Gene expression control by protein deubiquitinases

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

GMP synthetase stimulates histone H2B deubiquitylation by the epigenetic silencer USP7

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Biosynthetic enzyme GMP synthetase cooperates with ubiquitin-specific protease 7 in transcriptional regulation of ecdysteroid target genes

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Methionine adenosyltransferase II serves as a transcriptional corepressor of Maf oncoprotein

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Acetyl-CoA synthetase regulates histone acetylation and hippocampal memory.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Nuclear Acetyl-CoA Production by ACLY Promotes Homologous Recombination.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

ATP-citrate lyase links cellular metabolism to histone acetylation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

A nuclear pyruvate dehydrogenase complex is important for the generation of acetyl-CoA and histone acetylation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Nucleocytosolic acetyl-coenzyme a synthetase is required for histone acetylation and global transcription

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Acetate Recapturing by Nuclear Acetyl-CoA Synthetase 2 Prevents Loss of Histone Acetylation during Oxygen and Serum Limitation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Local histone acetylation by ACSS2 promotes gene transcription for lysosomal biogenesis and autophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Altered histone acetylation is associated with age-dependent memory impairment in mice.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Epigenomics of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Targeting histone-modifications in Alzheimer's disease. What is the evidence that this is a promising therapeutic avenue?

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Histone acetyltransferase p300 mediates histone acetylation of PS1 and BACE1 in a cellular model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Shaping vulnerability to addiction - the contribution of behavior, neural circuits and molecular mechanisms.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

A Functional 3'UTR Polymorphism (rs2235749) of Prodynorphin Alters microRNA-365 Binding in Ventral Striatonigral Neurons to Influence Novelty Seeking and Positive Reward Traits.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Striatal H3K27 Acetylation Linked to Glutamatergic Gene Dysregulation in Human Heroin Abusers Holds Promise as Therapeutic Target.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Epigenetic basis of opiate suppression of Bdnf gene expression in the ventral tegmental area

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Transcriptional and epigenetic mechanisms of addiction

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

An acetate switch regulates stress erythropoiesis

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

The acetate/ACSS2 switch regulates HIF-2 stress signaling in the tumor cell microenvironment

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Nuclear Localization of Mitochondrial TCA Cycle Enzymes as a Critical Step in Mammalian Zygotic Genome Activation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Association of MAMLD1 single-nucleotide polymorphisms with hypospadias in Chinese Han population.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

Metabolic Kinases Moonlighting as Protein Kinases.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0029-7

7 January 2021

New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29930302

12 December 2020

inferred from PubMed ID database lookup

NOK mediates glycolysis and nuclear PDC associated histone acetylation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29930302

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/S41580-018-0029-7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29930302%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29930302%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

PubMed publication ID

29930302

1 reference