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NF-κB signaling in inflammation
scientific article published on 14 July 2017
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Europe PubMed Central
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5661633
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title
NF-κB signaling in inflammation
(English)
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Europe PubMed Central
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5661633
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NF-κB
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Ting Liu
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1
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5661633
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Lingyun Zhang
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2
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Donghyun Joo
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5661633
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Shao-Cong Sun
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publication date
14 July 2017
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5661633
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3 April 2020
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2
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Europe PubMed Central
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5661633
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Creative Commons Attribution 4.0 International
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14 July 2017
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunopathology of inflammatory bowel disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear factor kappaB is activated in macrophages and epithelial cells of inflamed intestinal mucosa.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of nuclear factor kappa B inflammatory bowel disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional annotation of a novel NFKB1 promoter polymorphism that increases risk for ulcerative colitis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of the NFKB1 -94ins/delATTG promoter polymorphism in IBD and potential interactions with polymorphisms in the CARD15/NOD2, IKBL, and IL-1RN genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Damaging heterozygous mutations in NFKB1 lead to diverse immunologic phenotypes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Impaired regulation of NF-kappaB and increased susceptibility to colitis-associated tumorigenesis in CYLD-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deubiquitinating enzyme CYLD negatively regulates the ubiquitin-dependent kinase Tak1 and prevents abnormal T cell responses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A20 controls intestinal homeostasis through cell-specific activities
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kappa B abrogates established experimental colitis in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Treatment of murine Th1- and Th2-mediated inflammatory bowel disease with NF-kappa B decoy oligonucleotides
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Epithelial NEMO links innate immunity to chronic intestinal inflammation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Epithelial-cell-intrinsic IKK-β expression regulates intestinal immune homeostasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autoimmune T cell responses in the central nervous system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
GWAS analysis implicates NF-κB-mediated induction of inflammatory T cells in multiple sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibitors in the NFκB cascade comprise prime candidate genes predisposing to multiple sclerosis, especially in selected combinations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear factor kappa B (NF-κB) in multiple sclerosis pathology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The NF-κB regulator MALT1 determines the encephalitogenic potential of Th17 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T cell receptor/CARMA1/NF-κB signaling controls T-helper (Th) 17 differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Paracaspase MALT1 deficiency protects mice from autoimmune-mediated demyelination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Th17 immune response is controlled by the Rel-RORγ-RORγ T transcriptional axis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The NF- B Transcription Factor c-Rel Is Required for Th17 Effector Cell Development in Experimental Autoimmune Encephalomyelitis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NIK signaling in dendritic cells but not in T cells is required for the development of effector T cells and cell-mediated immune responses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of Th17 cell differentiation and EAE induction by MAP3K NIK.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Constitutive activity of NF-kappa B in myeloid cells drives pathogenicity of monocytes and macrophages during autoimmune neuroinflammation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IKKβ-mediated inflammatory myeloid cell activation exacerbates experimental autoimmune encephalomyelitis by potentiating Th1/Th17 cell activation and compromising blood brain barrier
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of transcription factor NF-κB in the central nervous system ameliorates autoimmune encephalomyelitis in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transgenic inhibition of astroglial NF-κB protects from optic nerve damage and retinal ganglion cell loss in experimental optic neuritis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transgenic inhibition of astroglial NF-kappa B improves functional outcome in experimental autoimmune encephalomyelitis by suppressing chronic central nervous system inflammation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Progress and challenges in translating the biology of atherosclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear Factor-κB Activation as a Pathological Mechanism of Lipid Metabolism and Atherosclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Canonical pathway of nuclear factor kappa B activation selectively regulates proinflammatory and prothrombotic responses in human atherosclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endothelial cell-specific NF-kappaB inhibition protects mice from atherosclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NF-kappaB controls the global pro-inflammatory response in endothelial cells: evidence for the regulation of a pro-atherogenic program
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear factor kappaB: a potential therapeutic target in atherosclerosis and thrombosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Macrophage-specific inhibition of NF-kappaB activation reduces foam-cell formation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Myeloid IκBα deficiency promotes atherogenesis by enhancing leukocyte recruitment to the plaques
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Myeloid-specific IκB kinase β deficiency decreases atherosclerosis in low-density lipoprotein receptor-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of NF-kappaB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The NF-kappaB activation pathways, emerging molecular targets for cancer prevention and therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSIGTRANS.2017.23
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High DNA-binding activity of transcription factor NF-kappa B in synovial membranes of patients with rheumatoid arthritis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/29158945
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Constitutive transcription of the human interleukin-6 gene by rheumatoid synoviocytes: spontaneous activation of NF-kappaB and CBF1.
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/29158945
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Preferential role for NF-kappa B/Rel signaling in the type 1 but not type 2 T cell-dependent immune response in vivo
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/29158945
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Molecular mechanisms that influence the macrophage m1-m2 polarization balance
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/29158945
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1038/SIGTRANS.2017.23
1 reference
stated in
Europe PubMed Central
PMCID
5661633
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29158945%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 April 2020
PMCID
5661633
1 reference
stated in
Europe PubMed Central
PMCID
5661633
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29158945%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 April 2020
PubMed ID
29158945
1 reference
stated in
Europe PubMed Central
PMCID
5661633
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29158945%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 April 2020
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