(Q90424222)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31575677%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

review article

1 reference

title

Kidney organoids: accurate models or fortunate accidents (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31575677%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

1 reference

1

Melissa H Little

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31575677%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

author name string

Alexander N Combes

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31575677%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

publication date

1 October 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31575677%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31575677%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

volume

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31575677%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

issue

19-20

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31575677%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

page(s)

1319-1345

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31575677%20AND%20SRC:MED&resulttype=core&format=json

Early organogenesis of the kidney

13 April 2020

cites work

1 reference

12 December 2020

Early innervation of the metanephric kidney

1 reference

12 December 2020

The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium

1 reference

12 December 2020

Repression of Pax-2 by WT1 during normal kidney development

1 reference

12 December 2020

Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4

1 reference

12 December 2020

Hematopoietic commitment during embryonic stem cell differentiation in culture

1 reference

12 December 2020

Embryonic stem cell lines derived from human blastocysts

1 reference

12 December 2020

Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation

1 reference

12 December 2020

Hox11 paralogous genes are essential for metanephric kidney induction

1 reference

12 December 2020

Sonic hedgehog regulates proliferation and differentiation of mesenchymal cells in the mouse metanephric kidney

1 reference

12 December 2020

Glomerular number and size in autopsy kidneys: the relationship to birth weight

1 reference

12 December 2020

Crucial roles of Brn1 in distal tubule formation and function in mouse kidney

1 reference

12 December 2020

Gamma-secretase activity is dispensable for mesenchyme-to-epithelium transition but required for podocyte and proximal tubule formation in developing mouse kidney

1 reference

12 December 2020

DEVELOPMENT OF HUMAN KIDNEY AS SHOWN BY MICRODISSECTION. III. FORMATION AND INTERRELATIONSHIP OF COLLECTING TUBULES AND NEPHRONS

1 reference

12 December 2020

Real-time analysis of ureteric bud branching morphogenesis in vitro

1 reference

12 December 2020

Morphometric index of the developing murine kidney

1 reference

12 December 2020

Forced aggregation of defined numbers of human embryonic stem cells into embryoid bodies fosters robust, reproducible hematopoietic differentiation.

1 reference

12 December 2020

Distinct and sequential tissue-specific activities of the LIM-class homeobox gene Lim1 for tubular morphogenesis during kidney development

1 reference

12 December 2020

Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system

1 reference

12 December 2020

Three-dimensional reconstruction of the mouse nephron

1 reference

12 December 2020

Transcriptional profiling of mouse and human ES cells identifies SLAIN1, a novel stem cell gene.

1 reference

12 December 2020

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

1 reference

12 December 2020

Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidney

1 reference

12 December 2020

Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron.

1 reference

12 December 2020

Glycogen synthase kinase-3 inactivation and stabilization of beta-catenin induce nephron differentiation in isolated mouse and rat kidney mesenchymes

1 reference

12 December 2020

A high-resolution anatomical ontology of the developing murine genitourinary tract.

1 reference

12 December 2020

Characterisation and trophic functions of murine embryonic macrophages based upon the use of a Csf1r-EGFP transgene reporter.

1 reference

12 December 2020

Cessation of renal morphogenesis in mice

1 reference

12 December 2020

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

1 reference

12 December 2020

Fate mapping using Cited1-CreERT2 mice demonstrates that the cap mesenchyme contains self-renewing progenitor cells and gives rise exclusively to nephronic epithelia.

1 reference

12 December 2020

Hoxd11 specifies a program of metanephric kidney development within the intermediate mesoderm of the mouse embryo.

1 reference

12 December 2020

Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development

1 reference

12 December 2020

Osr1 expression demarcates a multi-potent population of intermediate mesoderm that undergoes progressive restriction to an Osr1-dependent nephron progenitor compartment within the mammalian kidney

1 reference

12 December 2020

Self-organized formation of polarized cortical tissues from ESCs and its active manipulation by extrinsic signals

1 reference

12 December 2020

A Wnt7b-dependent pathway regulates the orientation of epithelial cell division and establishes the cortico-medullary axis of the mammalian kidney

1 reference

12 December 2020

Endocrine cells develop within pancreatic bud-like structures derived from mouse ES cells differentiated in response to BMP4 and retinoic acid

1 reference

12 December 2020

Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment.

1 reference

12 December 2020

Ret-dependent cell rearrangements in the Wolffian duct epithelium initiate ureteric bud morphogenesis.

1 reference

12 December 2020

The contribution of Notch1 to nephron segmentation in the developing kidney is revealed in a sensitized Notch2 background and can be augmented by reducing Mint dosage.

1 reference

12 December 2020

Dissociation of embryonic kidneys followed by reaggregation allows the formation of renal tissues

1 reference

12 December 2020

Notch2 activation in the embryonic kidney depletes nephron progenitors

1 reference

12 December 2020

Isolation of clonogenic, long-term self renewing embryonic renal stem cells

1 reference

12 December 2020

Patterning a complex organ: branching morphogenesis and nephron segmentation in kidney development

1 reference

12 December 2020

Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro

1 reference

12 December 2020

Canonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney development

1 reference

12 December 2020

Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways

1 reference

12 December 2020

Self-organizing optic-cup morphogenesis in three-dimensional culture

1 reference

12 December 2020

Expression of metanephric nephron-patterning genes in differentiating mesonephric tubules.

1 reference

12 December 2020

Nephron formation adopts a novel spatial topology at cessation of nephrogenesis.

1 reference

12 December 2020

Self-formation of functional adenohypophysis in three-dimensional culture.

1 reference

12 December 2020

FGF9 and FGF20 maintain the stemness of nephron progenitors in mice and man.

1 reference

12 December 2020

Lgr5(+ve) stem/progenitor cells contribute to nephron formation during kidney development.

1 reference

12 December 2020

Cytosystems dynamics in self-organization of tissue architecture

1 reference

12 December 2020

HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2

1 reference

12 December 2020

Tbx18 expression demarcates multipotent precursor populations in the developing urogenital system but is exclusively required within the ureteric mesenchymal lineage to suppress a renal stromal fate.

1 reference

12 December 2020

Direct transcriptional reprogramming of adult cells to embryonic nephron progenitors

1 reference

12 December 2020

Stromal-epithelial crosstalk regulates kidney progenitor cell differentiation

1 reference

12 December 2020

Cerebral organoids model human brain development and microcephaly

1 reference

12 December 2020

Directed differentiation of human pluripotent cells to ureteric bud kidney progenitor-like cells

1 reference

12 December 2020

Redefining the in vivo origin of metanephric nephron progenitors enables generation of complex kidney structures from pluripotent stem cells

1 reference

12 December 2020

Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidney

1 reference

12 December 2020

Single-gene causes of congenital anomalies of the kidney and urinary tract (CAKUT) in humans

1 reference

12 December 2020

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

1 reference

12 December 2020

Global quantification of tissue dynamics in the developing mouse kidney

1 reference

12 December 2020

Generation, expansion and functional analysis of endothelial cells and pericytes derived from human pluripotent stem cells

1 reference

12 December 2020

Organogenesis in a dish: modeling development and disease using organoid technologies

1 reference

12 December 2020

Induction and patterning of the metanephric nephron

1 reference

12 December 2020

Identification of a multipotent self-renewing stromal progenitor population during mammalian kidney organogenesis

1 reference

12 December 2020

Modelling human development and disease in pluripotent stem-cell-derived gastric organoids

1 reference

12 December 2020

An integrated pipeline for the multidimensional analysis of branching morphogenesis.

1 reference

12 December 2020

Eya1 interacts with Six2 and Myc to regulate expansion of the nephron progenitor pool during nephrogenesis

1 reference

12 December 2020

Nephron reconstitution from pluripotent stem cells

1 reference

12 December 2020

Integration of Cistromic and Transcriptomic Analyses Identifies Nphs2, Mafb, and Magi2 as Wilms' Tumor 1 Target Genes in Podocyte Differentiation and Maintenance

1 reference

12 December 2020

Genome-Wide Analysis of Wilms' Tumor 1-Controlled Gene Expression in Podocytes Reveals Key Regulatory Mechanisms

1 reference

12 December 2020

Integrated β-catenin, BMP, PTEN, and Notch signalling patterns the nephron

1 reference

12 December 2020

Deep Sequencing in Microdissected Renal Tubules Identifies Nephron Segment-Specific Transcriptomes

1 reference

12 December 2020

Improving our resolution of kidney morphogenesis across time and space

1 reference

12 December 2020

Alternatively spliced isoforms of WT1 control podocyte-specific gene expression

1 reference

12 December 2020

The origin of the mammalian kidney: implications for recreating the kidney in vitro

1 reference

12 December 2020

ROBO2 restricts the nephrogenic field and regulates Wolffian duct-nephrogenic cord separation

1 reference

12 December 2020

Stromal Fat4 acts non-autonomously with Dchs1/2 to restrict the nephron progenitor pool

1 reference

12 December 2020

A synthetic niche for nephron progenitor cells

1 reference

12 December 2020

Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis

1 reference

12 December 2020

Nephron organoids derived from human pluripotent stem cells model kidney development and injury

1 reference

12 December 2020

Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids

1 reference

12 December 2020

Human Induced Pluripotent Stem Cell-Derived Podocytes Mature into Vascularized Glomeruli upon Experimental Transplantation

1 reference

12 December 2020

Human cerebral organoids recapitulate gene expression programs of fetal neocortex development

1 reference

12 December 2020

Exploring the genetic basis of early-onset chronic kidney disease

1 reference

12 December 2020

Functional anterior pituitary generated in self-organizing culture of human embryonic stem cells

1 reference

12 December 2020

Differential regulation of mouse and human nephron progenitors by the Six family of transcriptional regulators

1 reference

12 December 2020

Selective In Vitro Propagation of Nephron Progenitors Derived from Embryos and Pluripotent Stem Cells.

1 reference

12 December 2020

Cap mesenchyme cell swarming during kidney development is influenced by attraction, repulsion, and adhesion to the ureteric tip.

1 reference

12 December 2020

Generation of kidney organoids from human pluripotent stem cells

1 reference

12 December 2020

3D Culture Supports Long-Term Expansion of Mouse and Human Nephrogenic Progenitors

1 reference

12 December 2020

Understanding kidney morphogenesis to guide renal tissue regeneration.

1 reference

12 December 2020

Notch signaling promotes nephrogenesis by downregulating Six2.

1 reference

12 December 2020

Differentiation of human embryonic stem cells to HOXA+ hemogenic vasculature that resembles the aorta-gonad-mesonephros.

1 reference

12 December 2020

Wnt/β-catenin promotes gastric fundus specification in mice and humans

1 reference

12 December 2020

Self-organisation after embryonic kidney dissociation is driven via selective adhesion of ureteric epithelial cells.

1 reference

12 December 2020

Cycles of vascular plexus formation within the nephrogenic zone of the developing mouse kidney

1 reference

12 December 2020

Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling.

1 reference

12 December 2020

Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development.

1 reference

12 December 2020

Neural Crest Cell Implantation Restores Enteric Nervous System Function and Alters the Gastrointestinal Transcriptome in Human Tissue-Engineered Small Intestine

1 reference

12 December 2020

Psychrophilic proteases dramatically reduce single-cell RNA-seq artifacts: a molecular atlas of kidney development

1 reference

12 December 2020

Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development

1 reference

12 December 2020

Organoid cystogenesis reveals a critical role of microenvironment in human polycystic kidney disease.

1 reference

12 December 2020

Mature induced-pluripotent-stem-cell-derived human podocytes reconstitute kidney glomerular-capillary-wall function on a chip

1 reference

12 December 2020

Notch is required for the formation of all nephron segments and primes nephron progenitors for differentiation

1 reference

12 December 2020

Higher-Order Kidney Organogenesis from Pluripotent Stem Cells.

1 reference

12 December 2020

Generation of branching ureteric bud tissues from human pluripotent stem cells.

1 reference

12 December 2020

Cross-platform single cell analysis of kidney development shows stromal cells express Gdnf.

1 reference

12 December 2020

In Vitro Induction and In Vivo Engraftment of Lung Bud Tip Progenitor Cells Derived from Human Pluripotent Stem Cells

1 reference

12 December 2020

Generation of Functioning Nephrons by Implanting Human Pluripotent Stem Cell-Derived Kidney Progenitors.

1 reference

12 December 2020

Conserved and Divergent Features of Mesenchymal Progenitor Cell Types within the Cortical Nephrogenic Niche of the Human and Mouse Kidney.

1 reference

12 December 2020

Conserved and Divergent Molecular and Anatomic Features of Human and Mouse Nephron Patterning.

1 reference

12 December 2020

Conserved and Divergent Features of Human and Mouse Kidney Organogenesis.

1 reference

12 December 2020

Renal Subcapsular Transplantation of PSC-Derived Kidney Organoids Induces Neo-vasculogenesis and Significant Glomerular and Tubular Maturation In Vivo.

1 reference

12 December 2020

Single-cell transcriptomics of the mouse kidney reveals potential cellular targets of kidney disease.

1 reference

12 December 2020

Simultaneous reprogramming and gene editing of human fibroblasts.

1 reference

12 December 2020

Spatiotemporal heterogeneity and patterning of developing renal blood vessels.

1 reference

12 December 2020

Patient-iPSC-Derived Kidney Organoids Show Functional Validation of a Ciliopathic Renal Phenotype and Reveal Underlying Pathogenetic Mechanisms

1 reference

12 December 2020

High-Throughput Screening Enhances Kidney Organoid Differentiation from Human Pluripotent Stem Cells and Enables Automated Multidimensional Phenotyping

1 reference

12 December 2020

Progressive Recruitment of Mesenchymal Progenitors Reveals a Time-Dependent Process of Cell Fate Acquisition in Mouse and Human Nephrogenesis

1 reference

12 December 2020

A Simple Bioreactor-Based Method to Generate Kidney Organoids from Pluripotent Stem Cells

1 reference

12 December 2020

A CRISP(e)R view on kidney organoids allows generation of an induced pluripotent stem cell-derived kidney model for drug discovery

1 reference

12 December 2020

Transplantation of human intestinal organoids into the mouse mesentery: A more physiologic and anatomic engraftment site

1 reference

12 December 2020

Ultrahigh thermal conductivity confirmed in boron arsenide

1 reference

12 December 2020

Single-cell analysis of progenitor cell dynamics and lineage specification in the human fetal kidney

1 reference

12 December 2020

Organoids from Nephrotic Disease-Derived iPSCs Identify Impaired NEPHRIN Localization and Slit Diaphragm Formation in Kidney Podocytes

1 reference

12 December 2020

Esophageal Organoids from Human Pluripotent Stem Cells Delineate Sox2 Functions during Esophageal Specification

1 reference

12 December 2020

Dissecting the Global Dynamic Molecular Profiles of Human Fetal Kidney Development by Single-Cell RNA Sequencing

1 reference

12 December 2020

Parallel generation of easily selectable multiple nephronal cell types from human pluripotent stem cells

1 reference

12 December 2020

Comparative Analysis and Refinement of Human PSC-Derived Kidney Organoid Differentiation with Single-Cell Transcriptomics

1 reference

12 December 2020

Vascularization and Engraftment of Transplanted Human Cerebral Organoids in Mouse Cortex

1 reference

12 December 2020

Vascular bioengineering of scaffolds derived from human discarded transplant kidneys using human pluripotent stem cell–derived endothelium

1 reference

12 December 2020

3D organoid-derived human glomeruli for personalised podocyte disease modelling and drug screening

1 reference

12 December 2020

Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment

1 reference

12 December 2020

Evaluation of variability in human kidney organoids

1 reference

12 December 2020

Organoid single cell profiling identifies a transcriptional signature of glomerular disease

1 reference

12 December 2020

Manipulation of Nephron-Patterning Signals Enables Selective Induction of Podocytes from Human Pluripotent Stem Cells

1 reference

12 December 2020

Single-cell analysis reveals congruence between kidney organoids and human fetal kidney

1 reference

12 December 2020

Nephron progenitor commitment is a stochastic process influenced by cell migration

1 reference

12 December 2020

Flow-enhanced vascularization and maturation of kidney organoids in vitro

1 reference

12 December 2020

Macrophages restrict the nephrogenic field and promote endothelial connections during kidney development

1 reference

12 December 2020

Fine tuning the extracellular environment accelerates the derivation of kidney organoids from human pluripotent stem cells

1 reference

12 December 2020

Single-cell transcriptomics reveals gene expression dynamics of human fetal kidney development

1 reference

12 December 2020

Scaffolding kidney organoids on silk

1 reference

12 December 2020

Kidney micro-organoids in suspension culture as a scalable source of human pluripotent stem cell-derived kidney cells

1 reference

12 December 2020

Reporter-based fate mapping in human kidney organoids confirms nephron lineage relationships and reveals synchronous nephron formation

1 reference

12 December 2020

Fibroblast growth factor signaling mediates progenitor cell aggregation and nephron regeneration in the adult zebrafish kidney

1 reference

12 December 2020

Correction: Single cell analysis of the developing mouse kidney provides deeper insight into marker gene expression and ligand-receptor crosstalk (doi:10.1242/dev.178673)

1 reference

12 December 2020

A Toolbox to Characterize Human Induced Pluripotent Stem Cell-Derived Kidney Cell Types and Organoids

1 reference

12 December 2020

Identifiers

DOI

10.1101/GAD.329573.119

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31575677%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31575677%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

1 reference