(Q91610063)

English

An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice

scientific article published on 06 April 2020

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32253226%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32253226%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

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Timothy P Sheahan

1

1 reference

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Rachel L. Graham

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Andrea J. Pruijssers

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Alexandra Schäfer

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Kenneth H Dinnon Iii

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Laura J. Stevens

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Amelia S. George

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Stephanie A Montgomery

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Gregory R Bluemling

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Jennifer L Harcourt

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Ronald Swanstrom

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Mark R. Denison

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Maria Luisa Agostini

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James David Chappell

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Natalie J Thornburg

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Ariane J. Brown

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Manohar Saindane

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2 references

Europe PubMed Central

PubMed publication ID

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Michael G. Natchus

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27 May 2020

publication date

6 April 2020

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32253226%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

Science Translational Medicine

2 references

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32253226%20AND%20SRC:MED&resulttype=core&format=json

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27 May 2020

A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19

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23 February 2021

Comparative pathogenesis of COVID-19, MERS, and SARS in a nonhuman primate model

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23 February 2021

Virological assessment of hospitalized patients with COVID-2019

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23 February 2021

Clinical and virological data of the first cases of COVID-19 in Europe: a case series

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23 February 2021

A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19

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Severe Acute Respiratory Syndrome Coronavirus 2 from Patient with 2019 Novel Coronavirus Disease, United States

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23 February 2021

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China

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Receptor Recognition by the Novel Coronavirus from Wuhan: an Analysis Based on Decade-Long Structural Studies of SARS Coronavirus

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Coronavirus Infections—More Than Just the Common Cold

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Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV

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Characterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia

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Small-Molecule Antiviral β-d--Hydroxycytidine Inhibits a Proofreading-Intact Coronavirus with a High Genetic Barrier to Resistance

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Broad spectrum antiviral remdesivir inhibits human endemic and zoonotic deltacoronaviruses with a highly divergent RNA dependent RNA polymerase

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Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors

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Mechanism of Inhibition of Ebola Virus RNA-Dependent RNA Polymerase by Remdesivir

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23 February 2021

Orally Efficacious Broad-Spectrum Ribonucleoside Analog Inhibitor of Influenza and Respiratory Syncytial Viruses

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Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease.

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Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses.

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Further Evidence for Bats as the Evolutionary Source of Middle East Respiratory Syndrome Coronavirus

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GS-5734 and its parent nucleoside analog inhibit Filo-, Pneumo-, and Paramyxoviruses

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Characterization of β-d-N4-Hydroxycytidine as a Novel Inhibitor of Chikungunya Virus

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A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7164393

23 February 2021

Systematic assembly of a full-length infectious cDNA of mouse hepatitis virus strain A59.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7164393

23 February 2021

Identifiers

10.1126/SCITRANSLMED.ABB5883

2 references

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32253226%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

10.1126/SCITRANSLMED.ABB5883

https://api.crossref.org/v1/works/http://dx.doi.org/10.1126/scitranslmed.abb5883

27 May 2020

0 references

PMC publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32253226%20AND%20SRC:MED&resulttype=core&format=json

23 April 2020

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