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Resistance to Anti-angiogenic Therapies: A Mechanism Depending on the Time of Exposure to the Drugs
scientific article published on 07 July 2020
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Europe PubMed Central
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7381352
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32775327%20AND%20SRC:MED&resulttype=core&format=json
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12 August 2020
title
Resistance to Anti-angiogenic Therapies: A Mechanism Depending on the Time of Exposure to the Drugs
(English)
1 reference
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Europe PubMed Central
PMCID
7381352
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32775327%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 August 2020
main subject
angiogenesis inhibitor
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Christopher Montemagno
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1
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Europe PubMed Central
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7381352
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32775327%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 August 2020
Gilles Pagès
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2
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Europe PubMed Central
PMCID
7381352
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32775327%20AND%20SRC:MED&resulttype=core&format=json
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12 August 2020
publication date
7 July 2020
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Europe PubMed Central
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12 August 2020
published in
Frontiers in Cell and Developmental Biology
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7381352
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12 August 2020
volume
8
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Europe PubMed Central
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7381352
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12 August 2020
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584
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Europe PubMed Central
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12 August 2020
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7 July 2020
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10 February 2021
Cabozantinib Versus Sunitinib As Initial Targeted Therapy for Patients With Metastatic Renal Cell Carcinoma of Poor or Intermediate Risk: The Alliance A031203 CABOSUN Trial.
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10 February 2021
MET: roles in epithelial-mesenchymal transition and cancer stemness
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10 February 2021
The Role of PDGFs and PDGFRs in Colorectal Cancer.
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10 February 2021
Sunitinib Stimulates Expression of VEGFC by Tumor Cells and Promotes Lymphangiogenesis in Clear Cell Renal Cell Carcinomas.
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10 February 2021
Induced cancer stem cells generated by radiochemotherapy and their therapeutic implications
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10 February 2021
Radiation induces the generation of cancer stem cells: A novel mechanism for cancer radioresistance
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10 February 2021
Vessel co-option mediates resistance to anti-angiogenic therapy in liver metastases
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10 February 2021
Adjuvant Sunitinib in High-Risk Renal-Cell Carcinoma after Nephrectomy
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10 February 2021
Pericyte-fibroblast transition promotes tumor growth and metastasis.
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10 February 2021
Escaping Antiangiogenic Therapy: Strategies Employed by Cancer Cells
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10 February 2021
Targeting renal cell carcinoma with a HIF-2 antagonist.
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10 February 2021
Everolimus affects vasculogenic mimicry in renal carcinoma resistant to sunitinib.
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10 February 2021
EphrinB2 repression through ZEB2 mediates tumour invasion and anti-angiogenic resistance
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10 February 2021
Periostin (POSTN) Regulates Tumor Resistance to Antiangiogenic Therapy in Glioma Models
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10 February 2021
Antagonist antibodies to vascular endothelial growth factor receptor 2 (VEGFR-2) as anti-angiogenic agents
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10 February 2021
Cabozantinib versus everolimus in advanced renal cell carcinoma (METEOR): final results from a randomised, open-label, phase 3 trial.
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10 February 2021
(125)I-labeled anti-bFGF monoclonal antibody inhibits growth of hepatocellular carcinoma
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10 February 2021
Targeting myeloid-derived suppressor cells with colony stimulating factor-1 receptor blockade can reverse immune resistance to immunotherapy in indoleamine 2,3-dioxygenase-expressing tumors
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10 February 2021
Targeting Metabolic Symbiosis to Overcome Resistance to Anti-angiogenic Therapy
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10 February 2021
Co-option of Liver Vessels and Not Sprouting Angiogenesis Drives Acquired Sorafenib Resistance in Hepatocellular Carcinoma
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10 February 2021
Adjuvant sunitinib or sorafenib for high-risk, non-metastatic renal-cell carcinoma (ECOG-ACRIN E2805): a double-blind, placebo-controlled, randomised, phase 3 trial
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10 February 2021
Functional and Biological Role of Endothelial Precursor Cells in Tumour Progression: A New Potential Therapeutic Target in Haematological Malignancies
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10 February 2021
Everolimus Versus Temsirolimus in Metastatic Renal Cell Carcinoma After Progression With Previous Systemic Therapies.
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10 February 2021
Independent assessment of lenvatinib plus everolimus in patients with metastatic renal cell carcinoma.
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10 February 2021
Fibrocyte-like cells mediate acquired resistance to anti-angiogenic therapy with bevacizumab.
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10 February 2021
Immunogenic, cellular, and angiogenic drivers of tumor dormancy--a melanoma view.
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10 February 2021
Lenvatinib, everolimus, and the combination in patients with metastatic renal cell carcinoma: a randomised, phase 2, open-label, multicentre trial
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10 February 2021
Inhibition of autophagy potentiates pemetrexed and simvastatin-induced apoptotic cell death in malignant mesothelioma and non-small cell lung cancer cells
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10 February 2021
Cancer-associated fibroblasts promote angiogenesis in gastric cancer through galectin-1 expression
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10 February 2021
Resistance to sunitinib in renal clear cell carcinoma results from sequestration in lysosomes and inhibition of the autophagic flux
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10 February 2021
Induction of epithelial-mesenchymal transition via activation of epidermal growth factor receptor contributes to sunitinib resistance in human renal cell carcinoma cell lines
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10 February 2021
VEGF Splicing and the Role of VEGF Splice Variants: From Physiological-Pathological Conditions to Specific Pre-mRNA Splicing
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10 February 2021
Histone Deacetylase Inhibitor Entinostat Inhibits Tumor-Initiating Cells in Triple-Negative Breast Cancer Cells
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10 February 2021
Macrophages and therapeutic resistance in cancer
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10 February 2021
The Fibroblast Growth Factor signaling pathway
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10 February 2021
The great escape; the hallmarks of resistance to antiangiogenic therapy.
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10 February 2021
Metabolic and hypoxic adaptation to anti-angiogenic therapy: a target for induced essentiality
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10 February 2021
VEGF-A modulates expression of inhibitory checkpoints on CD8+ T cells in tumors
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10 February 2021
Phase II trial of triple tyrosine kinase receptor inhibitor nintedanib in recurrent high-grade gliomas.
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10 February 2021
The autophagic response to radiation: relevance for radiation sensitization in cancer therapy
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10 February 2021
A phase II trial of brivanib in recurrent or persistent endometrial cancer: an NRG Oncology/Gynecologic Oncology Group Study.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Blocking lipid synthesis overcomes tumor regrowth and metastasis after antiangiogenic therapy withdrawal
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Anti-Bv8 antibody and metronomic gemcitabine improve pancreatic adenocarcinoma treatment outcome following weekly gemcitabine therapy
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10 February 2021
Targeting tumor-associated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapy
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10 February 2021
The role of the microenvironment-dormant prostate disseminated tumor cells in the bone marrow
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10 February 2021
Inhibition of Akt Reverses the Acquired Resistance to Sorafenib by Switching Protective Autophagy to Autophagic Cell Death in Hepatocellular Carcinoma
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Randomized, controlled, double-blind, cross-over trial assessing treatment preference for pazopanib versus sunitinib in patients with metastatic renal cell carcinoma: PISCES Study
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10 February 2021
Glycosylation-dependent lectin-receptor interactions preserve angiogenesis in anti-VEGF refractory tumors
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Galectin-1 Pulls the Strings on VEGFR2
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Hypoxia induces VEGF-C expression in metastatic tumor cells via a HIF-1α-independent translation-mediated mechanism
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10 February 2021
Dormancy in breast cancer
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10 February 2021
The CXCL7/CXCR1/2 axis is a key driver in the growth of clear cell renal cell carcinoma
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10 February 2021
β1 integrin: Critical path to antiangiogenic therapy resistance and beyond
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Epithelial-mesenchymal transition - activating transcription factors - multifunctional regulators in cancer
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Ang-2-VEGF-A CrossMab, a novel bispecific human IgG1 antibody blocking VEGF-A and Ang-2 functions simultaneously, mediates potent antitumor, antiangiogenic, and antimetastatic efficacy
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
A proangiogenic signature is revealed in FGF-mediated bevacizumab-resistant head and neck squamous cell carcinoma
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Lysyl oxidase secreted by tumour endothelial cells promotes angiogenesis and metastasis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Oxygen sensing, hypoxia-inducible factors, and disease pathophysiology
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Tumor cell-mediated neovascularization and lymphangiogenesis contrive tumor progression and cancer metastasis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Cell trafficking of endothelial progenitor cells in tumor progression
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
β1 integrin targeting potentiates antiangiogenic therapy and inhibits the growth of bevacizumab-resistant glioblastoma
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Axitinib versus sorafenib as second-line treatment for advanced renal cell carcinoma: overall survival analysis and updated results from a randomised phase 3 trial
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Glioblastoma stem cells generate vascular pericytes to support vessel function and tumor growth.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Effects of dual targeting of tumor cells and stroma in human glioblastoma xenografts with a tyrosine kinase inhibitor against c-MET and VEGFR2
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Hypoxia promotes tumor cell survival in acidic conditions by preserving ATP levels
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10 February 2021
A novel angiopoietin-2 selective fully human antibody with potent anti-tumoral and anti-angiogenic efficacy and superior side effect profile compared to Pan-Angiopoietin-1/-2 inhibitors
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10 February 2021
Galectin-1 promotes lung cancer tumor metastasis by potentiating integrin α6β4 and Notch1/Jagged2 signaling pathway
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Dichloroacetate reverses the hypoxic adaptation to bevacizumab and enhances its antitumor effects in mouse xenografts.
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10 February 2021
Gene expression profile identifies tyrosine kinase c-Met as a targetable mediator of antiangiogenic therapy resistance
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10 February 2021
Hyaluronan, fluid pressure, and stromal resistance in pancreas cancer.
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10 February 2021
Targeting activated Akt with GDC-0068, a novel selective Akt inhibitor that is efficacious in multiple tumor models
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10 February 2021
Cancer stem cells
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10 February 2021
Glioblastoma resistance to anti-VEGF therapy is associated with myeloid cell infiltration, stem cell accumulation, and a mesenchymal phenotype
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
The complex role of angiopoietin-2 in the angiopoietin-tie signaling pathway
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10 February 2021
Angiopoietins in angiogenesis
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10 February 2021
Lymphangiogenesis and cancer
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10 February 2021
Contrasting effects of sunitinib within in vivo models of metastasis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
VEGF inhibits tumor cell invasion and mesenchymal transition through a MET/VEGFR2 complex
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Anti-VEGF antibody therapy does not promote metastasis in genetically engineered mouse tumour models
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Differential drug class-specific metastatic effects following treatment with a panel of angiogenesis inhibitors
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PubMed Central
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10 February 2021
Suppression of tumor invasion and metastasis by concurrent inhibition of c-Met and VEGF signaling in pancreatic neuroendocrine tumors
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PubMed Central
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10 February 2021
Semaphorin 3A overcomes cancer hypoxia and metastatic dissemination induced by antiangiogenic treatment in mice
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PubMed Central
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10 February 2021
Molecular pathways: fibroblast growth factor signaling: a new therapeutic opportunity in cancer
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10 February 2021
Biglycan is a specific marker and an autocrine angiogenic factor of tumour endothelial cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Short-term anti-vascular endothelial growth factor treatment elicits vasculogenic mimicry formation of tumors to accelerate metastasis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
A novel monoclonal antibody to fibroblast growth factor 2 effectively inhibits growth of hepatocellular carcinoma xenografts
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Metabolism: Keeping fit with autophagy
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Pericyte depletion results in hypoxia-associated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Metabolic symbiosis in cancer: refocusing the Warburg lens
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10 February 2021
Integrins in tumor angiogenesis and lymphangiogenesis
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10 February 2021
Acceleration of clear cell renal cell carcinoma growth in mice following bevacizumab/Avastin treatment: the role of CXCL cytokines
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Platelet-derived growth factor signaling in human malignancies
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PubMed Central
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10 February 2021
Gene expression and hypoxia in breast cancer
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Normalization of the vasculature for treatment of cancer and other diseases
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
TGF-β receptor signaling pathways in angiogenesis; emerging targets for anti-angiogenesis therapy.
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10 February 2021
Targeting hypoxia in cancer therapy
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Angiopoietin-1 is essential in mouse vasculature during development and in response to injury
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Autophagy as a target for anticancer therapy
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10 February 2021
Angiopoietin-2 TIEs up macrophages in tumor angiogenesis.
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PubMed Central
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10 February 2021
Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Upregulated stromal EGFR and vascular remodeling in mouse xenograft models of angiogenesis inhibitor-resistant human lung adenocarcinoma
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Hallmarks of Cancer: The Next Generation
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10 February 2021
Antiangiogenic therapy: impact on invasion, disease progression, and metastasis.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
MDSC as a mechanism of tumor escape from sunitinib mediated anti-angiogenic therapy
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Hypoxia and energetic tumour metabolism
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
The bevacizumab experience in advanced renal cell carcinoma
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Identification of serum angiopoietin-2 as a biomarker for clinical outcome of colorectal cancer patients treated with bevacizumab-containing therapy
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Endothelial progenitor cells: hope beyond controversy
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Signaling by members of the TGF-beta family in vascular morphogenesis and disease
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Phase II study of cediranib, an oral pan-vascular endothelial growth factor receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Phase III trial of bevacizumab plus interferon alfa-2a in patients with metastatic renal cell carcinoma (AVOREN): final analysis of overall survival
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Stromal cell-derived factor-1/CXCL12 contributes to MMTV-Wnt1 tumor growth involving Gr1+CD11b+ cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
A human monoclonal anti-ANG2 antibody leads to broad antitumor activity in combination with VEGF inhibitors and chemotherapy agents in preclinical models
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Phase II trial of infusional fluorouracil, irinotecan, and bevacizumab for metastatic colorectal cancer: efficacy and circulating angiogenic biomarkers associated with therapeutic resistance
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Cytoprotective effect of imatinib mesylate in non-BCR-ABL-expressing cells along with autophagosome formation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Tumor and stromal pathways mediating refractoriness/resistance to anti-angiogenic therapies
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Antiangiogenic therapies for high-grade glioma
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Pleiotropic roles of matrix metalloproteinases in tumor angiogenesis: contrasting, overlapping and compensatory functions
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Human hepatocellular carcinoma tumor-derived endothelial cells manifest increased angiogenesis capability and drug resistance compared with normal endothelial cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Angiogenesis drives psoriasis pathogenesis
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Biomarkers for epithelial-mesenchymal transitions
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Role of the hypoxic tumor microenvironment in the resistance to anti-angiogenic therapies
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
G-CSF-initiated myeloid cell mobilization and angiogenesis mediate tumor refractoriness to anti-VEGF therapy in mouse models
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Sunitinib mediates reversal of myeloid-derived suppressor cell accumulation in renal cell carcinoma patients
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
The FGF family: biology, pathophysiology and therapy
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Angiopoietin-2 levels are associated with disease progression in metastatic malignant melanoma.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Diabetic retinopathy and angiogenesis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Imaging glioma cell invasion in vivo reveals mechanisms of dissemination and peritumoral angiogenesis
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Transforming growth factor-beta 1 (TGF-beta1) induces angiogenesis through vascular endothelial growth factor (VEGF)-mediated apoptosis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Targeting transforming growth factor (TGF)-betaRI inhibits activation of beta1 integrin and blocks vascular invasion in hepatocellular carcinoma
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Sunitinib reverses type-1 immune suppression and decreases T-regulatory cells in renal cell carcinoma patients
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Modes of resistance to anti-angiogenic therapy
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Sorafenib in advanced hepatocellular carcinoma
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Refractoriness to antivascular endothelial growth factor treatment: role of myeloid cells
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
The role of CXC chemokines and their receptors in cancer.
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10 February 2021
Vascular endothelial growth factor receptor 2 mediates macrophage infiltration into orthotopic pancreatic tumors in mice.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Tumor angiogenesis
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10 February 2021
Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Tumor-induced tolerance and immune suppression by myeloid derived suppressor cells.
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10 February 2021
Treatment of advanced renal cell carcinoma with the combination bevacizumab/erlotinib/imatinib: a phase I/II trial
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
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10 February 2021
Bv8 regulates myeloid-cell-dependent tumour angiogenesis
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10 February 2021
beta1 integrin as a molecular therapeutic target.
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10 February 2021
Autophagy: process and function
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10 February 2021
Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels
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10 February 2021
Role of autophagy in cancer
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10 February 2021
Multiple circulating proangiogenic factors induced by sunitinib malate are tumor-independent and correlate with antitumor efficacy
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10 February 2021
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10 February 2021
Tumor refractoriness to anti-VEGF treatment is mediated by CD11b+Gr1+ myeloid cells.
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10 February 2021
What tangled webs they weave: Rho-GTPase control of angiogenesis.
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10 February 2021
Expression of Tie-2 by human monocytes and their responses to angiopoietin-2
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PubMed Central
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10 February 2021
Absence of lymphangiogenesis in ductal breast cancer at the primary tumor site
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10 February 2021
Prognostic significance of vascular endothelial cell growth factors -A, -C and -D in breast cancer and their relationship with angio- and lymphangiogenesis
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10 February 2021
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10 February 2021
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10 February 2021
AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients.
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10 February 2021
Bevacizumab: an angiogenesis inhibitor for the treatment of solid malignancies
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10 February 2021
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10 February 2021
Inhibition of carcinoma cell-derived VEGF reduces inflammatory characteristics in xenograft carcinoma
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10 February 2021
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10 February 2021
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10 February 2021
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10 February 2021
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10 February 2021
Surrogate markers for antiangiogenic therapy and dose-limiting toxicities for bevacizumab with radiation and chemotherapy: continued experience of a phase I trial in rectal cancer patients
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10 February 2021
Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors
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10 February 2021
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10 February 2021
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10 February 2021
Epidermal growth factor receptor and angiogenesis: Opportunities for combined anticancer strategies
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10 February 2021
Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
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10 February 2021
PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumorigenesis of breast cancer cells.
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10 February 2021
Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy
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10 February 2021
A multitargeted, metronomic, and maximum-tolerated dose "chemo-switch" regimen is antiangiogenic, producing objective responses and survival benefit in a mouse model of cancer.
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10 February 2021
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10 February 2021
MT1-MMP-dependent neovessel formation within the confines of the three-dimensional extracellular matrix.
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10 February 2021
Ras-induced interleukin-8 expression plays a critical role in tumor growth and angiogenesis
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10 February 2021
Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis
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10 February 2021
Effects of Angiogenesis Inhibitors on Vascular Network Formation by Human Endothelial and Melanoma Cells
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10 February 2021
Antiangiogenic therapy of cerebral melanoma metastases results in sustained tumor progression via vessel co-option
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10 February 2021
Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1
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10 February 2021
VEGF-null cells require PDGFR alpha signaling-mediated stromal fibroblast recruitment for tumorigenesis
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10 February 2021
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10 February 2021
Hepatic expression of ANG2 RNA in metastatic colorectal cancer
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10 February 2021
Endothelial and nonendothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors
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10 February 2021
Identification of a cancer stem cell in human brain tumors
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10 February 2021
A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer
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10 February 2021
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10 February 2021
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10 February 2021
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10 February 2021
Angiopoietin-2 expression in breast cancer correlates with lymph node invasion and short survival.
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10 February 2021
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10 February 2021
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10 February 2021
Hemodynamics in vasculogenic mimicry and angiogenesis of inflammatory breast cancer xenograft
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10 February 2021
TGF-beta signaling in tumor suppression and cancer progression
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10 February 2021
Patterns of angiogenesis in nonsmall-cell lung carcinoma
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10 February 2021
Molecular determinants of ovarian cancer plasticity
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10 February 2021
How cells read TGF-beta signals
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10 February 2021
Involvement of chemokine receptors in breast cancer metastasis
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10 February 2021
Hepatocyte growth factor enhances vascular endothelial growth factor-induced angiogenesis in vitro and in vivo
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10 February 2021
Angiogenesis in wound healing
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10 February 2021
Angiogenesis in ovarian follicular and luteal development
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10 February 2021
Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis
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10 February 2021
Phenotypic and functional characteristics of tumour-derived microvascular endothelial cells
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10 February 2021
Transformation and Stat activation by derivatives of FGFR1, FGFR3, and FGFR4
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10 February 2021
Opposing effects of hypoxia on expression of the angiogenic inhibitor thrombospondin 1 and the angiogenic inducer vascular endothelial growth factor.
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10 February 2021
The effect of an individual's cytochrome CYP3A4 activity on docetaxel clearance
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10 February 2021
The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation
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10 February 2021
Vascular channel formation by human melanoma cells in vivo and in vitro: vasculogenic mimicry
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10 February 2021
The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis
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10 February 2021
Cell type-specific expression of angiopoietin-1 and angiopoietin-2 suggests a role in glioblastoma angiogenesis
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10 February 2021
Tie2 receptor ligands, angiopoietin-1 and angiopoietin-2, modulate VEGF-induced postnatal neovascularization
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10 February 2021
Activation of the MAP kinase pathway by FGF-1 correlates with cell proliferation induction while activation of the Src pathway correlates with migration
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
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10 February 2021
Neutralizing anti-vascular endothelial growth factor antibody completely inhibits angiogenesis and growth of human prostate carcinoma micro tumors in vivo
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10 February 2021
Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders
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10 February 2021
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10 February 2021
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10 February 2021
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10 February 2021
Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis
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10 February 2021
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10 February 2021
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10 February 2021
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10 February 2021
Angiostatin induces and sustains dormancy of human primary tumors in mice
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10 February 2021
A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases
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10 February 2021
Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities
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10 February 2021
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
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10 February 2021
Pathomorphologic characteristics of small hepatocellular carcinoma: a special reference to small hepatocellular carcinoma with indistinct margins
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10 February 2021
Inhibition of tumor growth and metastasis by an immunoneutralizing monoclonal antibody to human vascular endothelial growth factor/vascular permeability factor121
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10 February 2021
Dormancy of micrometastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppression
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10 February 2021
Regulation by vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastasis
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10 February 2021
Oxygen tension regulates the expression of angiogenesis factor by macrophages
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10 February 2021
Platelet-derived growth factor. II. Specific binding to cultured cells
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10 February 2021
Choriocarcinoma. Transfilter stimulation of vasoproliferation in the hamster cheek pouch. Studied by light and electron microscopy
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reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
retrieved
10 February 2021
Tumor angiogenesis: transfilter diffusion studies in the hamster by the transparent chamber technique
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
retrieved
10 February 2021
Serum factor requirements of normal and simian virus 40-transformed 3T3 mouse fibroplasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
retrieved
10 February 2021
Anti-angiogenesis: new concept for therapy of solid tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
retrieved
10 February 2021
Tumor angiogenesis: therapeutic implications
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
retrieved
10 February 2021
Inhibition of capillary endothelial cell growth by pericytes and smooth muscle cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
retrieved
10 February 2021
Role of a Na+-dependent Cl-/HCO3- exchange in regulation of intracellular pH in fibroblasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
retrieved
10 February 2021
Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
retrieved
10 February 2021
Vascular permeability factor, an endothelial cell mitogen related to PDGF
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
retrieved
10 February 2021
Vascular endothelial growth factor is a secreted angiogenic mitogen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
retrieved
10 February 2021
Transforming growth factor-alpha: a more potent angiogenic mediator than epidermal growth factor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
retrieved
10 February 2021
Angiogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7381352
retrieved
10 February 2021
Identifiers
DOI
10.3389/FCELL.2020.00584
1 reference
stated in
Europe PubMed Central
PMCID
7381352
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32775327%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 August 2020
PMCID
7381352
1 reference
stated in
Europe PubMed Central
PMCID
7381352
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32775327%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 August 2020
PubMed ID
32775327
1 reference
stated in
Europe PubMed Central
PMCID
7381352
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32775327%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 August 2020
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