(Q104492546)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33333068%20AND%20SRC:MED&resulttype=core&format=json

25 December 2020

title

Returning to kidney development to deliver synthetic kidneys (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33333068%20AND%20SRC:MED&resulttype=core&format=json

25 December 2020

M. H. Little

1

Melissa H. Little

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33333068%20AND%20SRC:MED&resulttype=core&format=json

25 December 2020

publication date

14 December 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33333068%20AND%20SRC:MED&resulttype=core&format=json

full work available at URL

25 December 2020

https://www.sciencedirect.com/science/article/pii/S0012160620303183

archive URL

https://web.archive.org/web/20230312064238/https://www.sciencedirect.com/science/article/pii/S0012160620303183

12 March 2023

0 references

Developmental Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:33333068%20AND%20SRC:MED&resulttype=core&format=json

Generation of Functioning Nephrons by Implanting Human Pluripotent Stem Cell-Derived Kidney Progenitors.

25 December 2020

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Metabolic Regulation of Human Pluripotent Stem Cell-Derived Cardiomyocyte Maturation

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7 January 2021

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Postembryonic Nephrogenesis and Persistence of Six2-Expressing Nephron Progenitor Cells in the Reptilian Kidney

7 January 2021

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Intrinsic Age-Dependent Changes and Cell-Cell Contacts Regulate Nephron Progenitor Lifespan

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7 January 2021

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Notch is required for the formation of all nephron segments and primes nephron progenitors for differentiation

7 January 2021

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7 January 2021

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Single-cell analysis reveals congruence between kidney organoids and human fetal kidney

7 January 2021

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Patterning a complex organ: branching morphogenesis and nephron segmentation in kidney development

7 January 2021

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Organoid cystogenesis reveals a critical role of microenvironment in human polycystic kidney disease.

7 January 2021

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High-Throughput Screening Enhances Kidney Organoid Differentiation from Human Pluripotent Stem Cells and Enables Automated Multidimensional Phenotyping

7 January 2021

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Spatiotemporal heterogeneity and patterning of developing renal blood vessels.

7 January 2021

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Stromal-epithelial crosstalk regulates kidney progenitor cell differentiation

7 January 2021

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Using synthetic biology to explore principles of development

7 January 2021

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Nephron Patterning: Lessons from Xenopus, Zebrafish, and Mouse Studies

7 January 2021

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Identification of adult nephron progenitors capable of kidney regeneration in zebrafish

7 January 2021

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Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy

7 January 2021

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Self-organizing optic-cup morphogenesis in three-dimensional culture

7 January 2021

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Identification and characterization of cellular heterogeneity within the developing renal interstitium

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Establishment in culture of pluripotential cells from mouse embryos

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Patient-iPSC-Derived Kidney Organoids Show Functional Validation of a Ciliopathic Renal Phenotype and Reveal Underlying Pathogenetic Mechanisms

7 January 2021

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Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids

7 January 2021

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Fibroblast growth factor signaling mediates progenitor cell aggregation and nephron regeneration in the adult zebrafish kidney

7 January 2021

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Fine tuning the extracellular environment accelerates the derivation of kidney organoids from human pluripotent stem cells

7 January 2021

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Programmed assembly of 3-dimensional microtissues with defined cellular connectivity

7 January 2021

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Analysis of early nephron patterning reveals a role for distal RV proliferation in fusion to the ureteric tip via a cap mesenchyme-derived connecting segment.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Expression of metanephric nephron-patterning genes in differentiating mesonephric tubules.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

3D organoid-derived human glomeruli for personalised podocyte disease modelling and drug screening

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Cessation of renal morphogenesis in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Direct transcriptional reprogramming of adult cells to embryonic nephron progenitors

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Induction of human pluripotent stem cells into kidney tissues by synthetic mRNAs encoding transcription factors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Single-cell transcriptomics reveals gene expression dynamics of human fetal kidney development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Bioprinting of 3D Convoluted Renal Proximal Tubules on Perfusable Chips

7 January 2021

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Flow-enhanced vascularization and maturation of kidney organoids in vitro

7 January 2021

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Reporter-based fate mapping in human kidney organoids confirms nephron lineage relationships and reveals synchronous nephron formation

7 January 2021

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Glomerular number and size in autopsy kidneys: the relationship to birth weight

7 January 2021

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Human haematopoietic stem cell development: from the embryo to the dish

7 January 2021

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Wnt signaling mediates new nephron formation during zebrafish kidney regeneration

7 January 2021

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Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors.

7 January 2021

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Invasion of distal nephron precursors associates with tubular interconnection during nephrogenesis.

7 January 2021

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Wnt9b signaling regulates planar cell polarity and kidney tubule morphogenesis

7 January 2021

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Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development

7 January 2021

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Identification of a multipotent self-renewing stromal progenitor population during mammalian kidney organogenesis

7 January 2021

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Kidney micro-organoids in suspension culture as a scalable source of human pluripotent stem cell-derived kidney cells

7 January 2021

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PKD1-Dependent Renal Cystogenesis in Human Induced Pluripotent Stem Cell-Derived Ureteric Bud/Collecting Duct Organoids

7 January 2021

1 reference

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Cerebral organoids model human brain development and microcephaly

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Nephron progenitor commitment is a stochastic process influenced by cell migration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Cellular extrusion bioprinting improves kidney organoid reproducibility and conformation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Self-organisation after embryonic kidney dissociation is driven via selective adhesion of ureteric epithelial cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

3D Culture Supports Long-Term Expansion of Mouse and Human Nephrogenic Progenitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Renal reabsorption in 3D vascularized proximal tubule models

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Progressive Recruitment of Mesenchymal Progenitors Reveals a Time-Dependent Process of Cell Fate Acquisition in Mouse and Human Nephrogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Conserved and Divergent Features of Mesenchymal Progenitor Cell Types within the Cortical Nephrogenic Niche of the Human and Mouse Kidney.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Conserved and Divergent Features of Human and Mouse Kidney Organogenesis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Kidney organoids: accurate models or fortunate accidents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Regulation of Nephron Progenitor Cell Self-Renewal by Intermediary Metabolism.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Generation of Human PSC-Derived Kidney Organoids with Patterned Nephron Segments and a De Novo Vascular Network

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Generation of branching ureteric bud tissues from human pluripotent stem cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Expansion of Human iPSC-Derived Ureteric Bud Organoids with Repeated Branching Potential

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Direct lineage conversion of terminally differentiated hepatocytes to functional neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Single-cell analysis of progenitor cell dynamics and lineage specification in the human fetal kidney

7 January 2021

1 reference

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Synthetic embryology: controlling geometry to model early mammalian development

7 January 2021

1 reference

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Development of the renal vasculature

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Nephron organoids derived from human pluripotent stem cells model kidney development and injury

7 January 2021

1 reference

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Differentiation of human embryonic stem cells and induced pluripotent stem cells to cardiomyocytes: a methods overview

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Mature induced-pluripotent-stem-cell-derived human podocytes reconstitute kidney glomerular-capillary-wall function on a chip

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Correction to: Graft immaturity and safety concerns in transplanted human kidney organoids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Inactivation of FGF8 in early mesoderm reveals an essential role in kidney development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Evaluation of variability in human kidney organoids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

A Simple Bioreactor-Based Method to Generate Kidney Organoids from Pluripotent Stem Cells

7 January 2021

1 reference

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A predictive computational framework for direct reprogramming between human cell types

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Characterisation and trophic functions of murine embryonic macrophages based upon the use of a Csf1r-EGFP transgene reporter.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Single-Cell Profiling Reveals Sex, Lineage, and Regional Diversity in the Mouse Kidney

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Effect of Luminal Flow on Doming of mpkCCD Cells in a 3D Perfusable Kidney Cortical Collecting Duct Model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Nephron formation adopts a novel spatial topology at cessation of nephrogenesis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Development of the Human Fetal Kidney from Mid to Late Gestation in Male and Female Infants.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Differentiation of a Contractile, Ureter-Like Tissue, from Embryonic Stem Cell-Derived Ureteric Bud and Ex Fetu Mesenchyme

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

A pluripotent stem cell-based model for post-implantation human amniotic sac development.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Human Induced Pluripotent Stem Cell-Derived Podocytes Mature into Vascularized Glomeruli upon Experimental Transplantation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Global quantification of tissue dynamics in the developing mouse kidney

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Branching morphogenesis in the developing kidney is not impacted by nephron formation or integration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Generation and assembly of human brain region-specific three-dimensional cultures.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

The directed differentiation of human iPS cells into kidney podocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Advances in predictive in vitro models of drug-induced nephrotoxicity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Self-Organization of Mouse Stem Cells into an Extended Potential Blastoid

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Does differential adhesion govern self-assembly processes in histogenesis? Equilibrium configurations and the emergence of a hierarchy among populations of embryonic cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Single cell census of human kidney organoids shows reproducibility and diminished off-target cells after transplantation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Self-formation of functional adenohypophysis in three-dimensional culture.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Higher-Order Kidney Organogenesis from Pluripotent Stem Cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Redefining the in vivo origin of metanephric nephron progenitors enables generation of complex kidney structures from pluripotent stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidney

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Wnt4 induces nephronic tubules in metanephric mesenchyme by a non-canonical mechanism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Selective In Vitro Propagation of Nephron Progenitors Derived from Embryos and Pluripotent Stem Cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Organoids from Nephrotic Disease-Derived iPSCs Identify Impaired NEPHRIN Localization and Slit Diaphragm Formation in Kidney Podocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Lumen Formation Is an Intrinsic Property of Isolated Human Pluripotent Stem Cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Embryonic stem cell lines derived from human blastocysts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Programmed synthesis of three-dimensional tissues.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

DIFFERENTIATION IN CULTURE OF MIXED AGGREGATES OF DISSOCIATED TISSUE CELLS.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

In Vivo Assessment of Size-Selective Glomerular Sieving in Transplanted Human Induced Pluripotent Stem Cell-Derived Kidney Organoids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Renal Subcapsular Transplantation of PSC-Derived Kidney Organoids Induces Neo-vasculogenesis and Significant Glomerular and Tubular Maturation In Vivo.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Direct reprogramming to human nephron progenitor-like cells using inducible piggyBac transposon expression of SNAI2-EYA1-SIX1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

A Toolbox to Characterize Human Induced Pluripotent Stem Cell-Derived Kidney Cell Types and Organoids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Direct conversion of fibroblasts to functional neurons by defined factors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Guiding Cell Network Assembly using Shape-Morphing Hydrogels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

A method to recapitulate early embryonic spatial patterning in human embryonic stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

RECONSTITUTION OF COMPLETE ORGANS FROM SINGLE-CELL SUSPENSIONS OF CHICK EMBRYOS IN ADVANCED STAGES OF DIFFERENTIATION.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

The zebrafish pronephros: a model to study nephron segmentation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Conversion of human and mouse fibroblasts into lung-like epithelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Comparative Analysis and Refinement of Human PSC-Derived Kidney Organoid Differentiation with Single-Cell Transcriptomics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

Manipulation of Nephron-Patterning Signals Enables Selective Induction of Podocytes from Human Pluripotent Stem Cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

A Wnt7b-dependent pathway regulates the orientation of epithelial cell division and establishes the cortico-medullary axis of the mammalian kidney

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009

In Vitro Propagation and Branching Morphogenesis from Single Ureteric Bud Cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2020.12.009