(Q107075962)

1

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Cátia Bárria

2

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Vanessa Costa

3

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Caio S. Souza

4

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Sandra C. Viegas

5

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Susana Domingues

6

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Diana Lousa

7

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Cláudio M Soares

8

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Cecília M Arraiano

9

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Rute G. Matos

Characteristics of SARS-CoV-2 and COVID-19

10

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publication date

7 January 2021

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cites work

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Human Coronavirus: Host-Pathogen Interaction

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

The critical role of RNA processing and degradation in the control of gene expression.

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Ribonucleases, antisense RNAs and the control of bacterial plasmids

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

The role of RNases in the regulation of small RNAs

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

The Implication of mRNA Degradation Disorders on Human DISease: Focus on DIS3 and DIS3-Like Enzymes

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

The Curious Case of the Nidovirus Exoribonuclease: Its Role in RNA Synthesis and Replication Fidelity

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Exoribonuclease superfamilies: structural analysis and phylogenetic distribution

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Structural basis for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

A general two-metal-ion mechanism for catalytic RNA

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Unique and conserved features of genome and proteome of SARS-coronavirus, an early split-off from the coronavirus group 2 lineage

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

A pneumonia outbreak associated with a new coronavirus of probable bat origin

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

The enzymatic activity of the nsp14 exoribonuclease is critical for replication of MERS-CoV and SARS-CoV-2

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

RNA 3'-end mismatch excision by the severe acute respiratory syndrome coronavirus nonstructural protein nsp10/nsp14 exoribonuclease complex

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Structural basis and functional analysis of the SARS coronavirus nsp14-nsp10 complex

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Characterization of the guanine-N7 methyltransferase activity of coronavirus nsp14 on nucleotide GTP.

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Biochemical and Structural Insights into the Mechanisms of SARS Coronavirus RNA Ribose 2′-O-Methylation by nsp16/nsp10 Protein Complex

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA templates

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Comparative protein modelling by satisfaction of spatial restraints

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Statistical potential for assessment and prediction of protein structures

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Coronavirus Nsp10, a critical co-factor for activation of multiple replicative enzymes

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Dodecamer structure of severe acute respiratory syndrome coronavirus nonstructural protein nsp10.

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Discovery of an RNA virus 3'->5' exoribonuclease that is critically involved in coronavirus RNA synthesis

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Characterisation of the SARS-CoV-2 ExoN (nsp14ExoN-nsp10) complex: implications for its role in viral genome stability and inhibitor identification

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Biochemical characterization of exoribonuclease encoded by SARS coronavirus

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Sinorhizobium meliloti YbeY is an endoribonuclease with unprecedented catalytic features, acting as silencing enzyme in riboregulation

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

RNase III: Catalytic Features and Impact on Symbiosis

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Genetic and crystallographic studies of the 3',5'-exonucleolytic site of DNA polymerase I.

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Crystal Structure of Non-Structural Protein 10 from Severe Acute Respiratory Syndrome Coronavirus-2

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Murine hepatitis virus replicase protein nsp10 is a critical regulator of viral RNA synthesis

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Molecular mapping of the RNA Cap 2'-O-methyltransferase activation interface between severe acute respiratory syndrome coronavirus nsp10 and nsp16.

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Structure-function analysis of severe acute respiratory syndrome coronavirus RNA cap guanine-N7-methyltransferase.

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

In vitro reconstitution of SARS-coronavirus mRNA cap methylation

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Infidelity of SARS-CoV Nsp14-exonuclease mutant virus replication is revealed by complete genome sequencing

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

High fidelity of murine hepatitis virus replication is decreased in nsp14 exoribonuclease mutants.

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA.

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Crystal structure of SARS-CoV-2 nsp10/nsp16 2'-O-methylase and its implication on antiviral drug design

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Coronavirus nsp10/nsp16 Methyltransferase Can Be Targeted by nsp10-Derived Peptide In Vitro and In Vivo To Reduce Replication and Pathogenesis

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Proofreading-Deficient Coronaviruses Adapt for Increased Fitness over Long-Term Passage without Reversion of Exoribonuclease-Inactivating Mutations.

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Coronaviruses lacking exoribonuclease activity are susceptible to lethal mutagenesis: evidence for proofreading and potential therapeutics

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease.

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Remdesivir and SARS-CoV-2: Structural requirements at both nsp12 RdRp and nsp14 Exonuclease active-sites

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

In silico structure modelling of SARS-CoV-2 Nsp13 helicase and Nsp14 and repurposing of FDA approved antiviral drugs as dual inhibitors

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Innate immune restriction and antagonism of viral RNA lacking 2׳-O methylation

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

2'-O methylation of the viral mRNA cap evades host restriction by IFIT family members

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

mRNA capping: biological functions and applications

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

RIG-I-like receptors: their regulation and roles in RNA sensing

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

SARS-CoV-2 nsp13, nsp14, nsp15 and orf6 function as potent interferon antagonists

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Severe acute respiratory syndrome coronavirus E protein transports calcium ions and activates the NLRP3 inflammasome

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745

Interaction of viral proteins with metal ions: role in maintaining the structure and functions of viruses

2 June 2021

1 reference

https://api.crossref.org/works/10.1101/2021.01.07.425745