(Q99557062)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32938769%20AND%20SRC:MED&resulttype=core&format=json

24 September 2020

title

The enzymatic activity of the nsp14 exoribonuclease is critical for replication of MERS-CoV and SARS-CoV-2 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32938769%20AND%20SRC:MED&resulttype=core&format=json

24 September 2020

1 reference

Non-structural protein 14 [SARS-CoV-2]

1 reference

based on heuristic

inferred from abstract

Middle East respiratory syndrome coronavirus

0 references

3

Yvonne van der Meer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32938769%20AND%20SRC:MED&resulttype=core&format=json

24 September 2020

author name string

Natacha S Ogando

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32938769%20AND%20SRC:MED&resulttype=core&format=json

24 September 2020

Jessika C Zevenhoven-Dobbe

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32938769%20AND%20SRC:MED&resulttype=core&format=json

24 September 2020

Peter J Bredenbeek

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32938769%20AND%20SRC:MED&resulttype=core&format=json

24 September 2020

Clara C Posthuma

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32938769%20AND%20SRC:MED&resulttype=core&format=json

24 September 2020

Eric J Snijder

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32938769%20AND%20SRC:MED&resulttype=core&format=json

24 September 2020

publication date

16 September 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32938769%20AND%20SRC:MED&resulttype=core&format=json

24 September 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32938769%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

24 September 2020

ImageQuant

object named as

ImageQuant TL

1 reference

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

cites work

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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Unique and conserved features of genome and proteome of SARS-coronavirus, an early split-off from the coronavirus group 2 lineage

27 December 2020

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Exoribonuclease superfamilies: structural analysis and phylogenetic distribution

27 December 2020

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27 December 2020

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Discovery of an RNA virus 3'->5' exoribonuclease that is critically involved in coronavirus RNA synthesis

27 December 2020

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Structural basis and functional analysis of the SARS coronavirus nsp14-nsp10 complex

27 December 2020

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Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA.

27 December 2020

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High fidelity of murine hepatitis virus replication is decreased in nsp14 exoribonuclease mutants.

27 December 2020

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Infidelity of SARS-CoV Nsp14-exonuclease mutant virus replication is revealed by complete genome sequencing

27 December 2020

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A live, impaired-fidelity coronavirus vaccine protects in an aged, immunocompromised mouse model of lethal disease

27 December 2020

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In vitro reconstitution of SARS-coronavirus mRNA cap methylation

27 December 2020

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RNA 3'-end mismatch excision by the severe acute respiratory syndrome coronavirus nonstructural protein nsp10/nsp14 exoribonuclease complex

27 December 2020

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One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities

27 December 2020

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Coronaviruses lacking exoribonuclease activity are susceptible to lethal mutagenesis: evidence for proofreading and potential therapeutics

27 December 2020

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Proofreading-Deficient Coronaviruses Adapt for Increased Fitness over Long-Term Passage without Reversion of Exoribonuclease-Inactivating Mutations.

27 December 2020

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The coronavirus proofreading exoribonuclease mediates extensive viral recombination

27 December 2020

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Arenaviridae exoribonuclease presents genomic RNA edition capacity

27 December 2020

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Structure of the Lassa virus nucleoprotein reveals a dsRNA-specific 3' to 5' exonuclease activity essential for immune suppression

27 December 2020

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The exonuclease domain of Lassa virus nucleoprotein is involved in antigen-presenting-cell-mediated NK cell responses

27 December 2020

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Mutagenesis of Coronavirus nsp14 Reveals Its Potential Role in Modulation of the Innate Immune Response.

27 December 2020

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Murine hepatitis virus nsp14 exoribonuclease activity is required for resistance to innate immunity

27 December 2020

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Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase

27 December 2020

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Characterization of the guanine-N7 methyltransferase activity of coronavirus nsp14 on nucleotide GTP.

27 December 2020

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Structure-function analysis of severe acute respiratory syndrome coronavirus RNA cap guanine-N7-methyltransferase.

27 December 2020

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Mutagenesis of S-Adenosyl-l-Methionine-Binding Residues in Coronavirus nsp14 N7-Methyltransferase Demonstrates Differing Requirements for Genome Translation and Resistance to Innate Immunity.

27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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Bioinformatics and functional analyses of coronavirus nonstructural proteins involved in the formation of replicative organelles

27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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Alisporivir inhibits MERS- and SARS-coronavirus replication in cell culture, but not SARS-coronavirus infection in a mouse model

27 December 2020

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MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-α treatment

27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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Coronavirus nsp10/nsp16 Methyltransferase Can Be Targeted by nsp10-Derived Peptide In Vitro and In Vivo To Reduce Replication and Pathogenesis

27 December 2020

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The 3'-5' exonuclease of DNA polymerase I of Escherichia coli: contribution of each amino acid at the active site to the reaction

27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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A molecular pore spans the double membrane of the coronavirus replication organelle

27 December 2020

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Characterization of Bafinivirus main protease autoprocessing activities

27 December 2020

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The Nonstructural Proteins Directing Coronavirus RNA Synthesis and Processing.

27 December 2020

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Arterivirus Nsp1 modulates the accumulation of minus-strand templates to control the relative abundance of viral mRNAs

27 December 2020

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En passant mutagenesis: a two step markerless red recombination system.

27 December 2020

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Reverse genetic characterization of the natural genomic deletion in SARS-Coronavirus strain Frankfurt-1 open reading frame 7b reveals an attenuating function of the 7b protein in-vitro and in-vivo

27 December 2020

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27 December 2020

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Establishment of the eukaryotic cell lines for inducible control of SARS-CoV nucleocapsid gene expression

27 December 2020

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Double-stranded RNA is produced by positive-strand RNA viruses and DNA viruses but not in detectable amounts by negative-strand RNA viruses

27 December 2020

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27 December 2020

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27 December 2020

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27 December 2020

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Biochemical and Structural Insights into the Mechanisms of SARS Coronavirus RNA Ribose 2′-O-Methylation by nsp16/nsp10 Protein Complex

27 December 2020

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Toward the identification of viral cap-methyltransferase inhibitors by fluorescence screening assay

27 December 2020

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27 December 2020

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27 December 2020

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Structural basis for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism

27 December 2020

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Characterisation of the SARS-CoV-2 ExoN (nsp14ExoN-nsp10) complex: implications for its role in viral genome stability and inhibitor identification

0 references

Identifiers

DOI

10.1128/JVI.01246-20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32938769%20AND%20SRC:MED&resulttype=core&format=json

24 September 2020

1 reference