(Q24299645)

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Redistribution of DAT/α-synuclein complexes visualized by "in situ" proximity ligation assay in transgenic mice modelling early Parkinson's disease

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scholarly article

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Redistribution of DAT/α-synuclein complexes visualized by "in situ" proximity ligation assay in transgenic mice modelling early Parkinson's disease (English)

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Parkinson's disease

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based on heuristic

inferred from title

Solute carrier family 6 (neurotransmitter transporter, dopamine), member 3

1 reference

GOA release 2020-03-11

Synuclein, alpha

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GOA release 2020-03-11

1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

Maria Grazia Spillantini

7

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Arianna Bellucci

object named as

Arianna Bellucci

1

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PierFranco Spano

object named as

Pierfranco Spano

10

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author name string

Laura Navarria

2

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Elisa Falarti

3

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Michela Zaltieri

4

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Federica Bono

5

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Ginetta Collo

6

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Maria Grazia

8

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Cristina Missale

9

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language of work or name

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publication date

2011

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6

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e27959

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12

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copyright license

Creative Commons Attribution 4.0 International

7 December 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

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Characterizing proteins and their interactions in cells and tissues using the in situ proximity ligation assay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

19 March 2017

Deletion of the alpha-synuclein locus in a subpopulation of C57BL/6J inbred mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

19 March 2017

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

19 March 2017

Alpha-synuclein in Lewy bodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

19 March 2017

Syntaxin 1A interaction with the dopamine transporter promotes amphetamine-induced dopamine efflux

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

19 March 2017

α-Synuclein stimulates a dopamine transporter-dependent chloride current and modulates the activity of the transporter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

Synuclein modulation of monoamine transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

Induction of the unfolded protein response by α-synuclein in experimental models of Parkinson's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

Profiling protein expression and interactions: proximity ligation as a tool for personalized medicine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

Postendocytic sorting of constitutively internalized dopamine transporter in cell lines and dopaminergic neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

Dopamine transporter trafficking: rapid response on demand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

Regulation of dopamine transporter function by protein-protein interactions: new discoveries and methodological challenges.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

Molecular interaction of α-synuclein with tubulin influences on the polymerization of microtubule in vitro and structure of microtubule in cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

Rab 11 regulates constitutive dopamine transporter trafficking and function in N2A neuroblastoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

{alpha}-synuclein and its A30P mutant affect actin cytoskeletal structure and dynamics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

Dopamine spillover after quantal release: rethinking dopamine transmission in the nigrostriatal pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

Regulation of dopamine transporter function and cell surface expression by D3 dopamine receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

Neuropathology, biochemistry, and biophysics of alpha-synuclein aggregation

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

29 November 2018

Physiological and pathological properties of alpha-synuclein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

Cell systems and the toxic mechanism(s) of alpha-synuclein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

D2 receptors regulate dopamine transporter function via an extracellular signal-regulated kinases 1 and 2-dependent and phosphoinositide 3 kinase-independent mechanism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

RNA interference-mediated knockdown of alpha-synuclein protects human dopaminergic neuroblastoma cells from MPP(+) toxicity and reduces dopamine transport.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

Disruption of the interaction of alpha-synuclein with microtubules enhances cell surface recruitment of the dopamine transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

The biochemistry of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

A precipitating role for truncated alpha-synuclein and the proteasome in alpha-synuclein aggregation: implications for pathogenesis of Parkinson disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

Aggregation promoting C-terminal truncation of alpha-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

Induction of inflammatory mediators and microglial activation in mice transgenic for mutant human P301S tau protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

Terminally differentiated SH-SY5Y cells provide a model system for studying neuroprotective effects of dopamine agonists.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

DAncing past the DAT at a DA synapse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

Comparative analyses of alpha-synuclein expression levels in rat brain tissues and transfected cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

Mutations in the lipid-binding domain of α-synuclein confer overlapping, yet distinct, functional properties in the regulation of dopamine transporter activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

Attenuation of dopamine transporter activity by alpha-synuclein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

Cocaine increases dopamine uptake and cell surface expression of dopamine transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

The solubility of alpha-synuclein in multiple system atrophy differs from that of dementia with Lewy bodies and Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

Immunocytochemical localization of the dopamine transporter in human brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

Subcellular localization and molecular topology of the dopamine transporter in the striatum and substantia nigra

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

The dopamine transporter is localized to dendritic and axonal plasma membranes of nigrostriatal dopaminergic neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

The regulation of synaptic function by alpha-synuclein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

27 September 2017

Decreased reuptake of dopamine in the dorsal striatum in the absence of α-synuclein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

30 May 2018

Cholinergic dysfunction, neuronal damage and axonal loss in TgCRND8 mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

30 May 2018

Synthetic filaments assembled from C-terminally truncated alpha-synuclein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233557

30 May 2018

Nigral burden of alpha-synuclein correlates with striatal dopamine deficit

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0027959

21 January 2018

Alpha-synuclein aggregation and cell death triggered by energy deprivation and dopamine overload are counteracted by D2/D3 receptor activation

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0027959

21 January 2018

Cocaine induction of dopamine transporter trafficking to the plasma membrane

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0027959

21 January 2018

Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human alpha-synuclein(1-120): implications for Lewy body disorders.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0027959

21 January 2018

Epitope mapping and specificity of the anti-alpha-synuclein monoclonal antibody Syn-1 in mouse brain and cultured cell lines.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0027959

21 January 2018

Ubiquitination of alpha-synuclein in Lewy bodies is a pathological event not associated with impairment of proteasome function

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0027959

21 January 2018

Role of alpha-synuclein carboxy-terminus on fibril formation in vitro.

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21 January 2018

Co-expression of C-terminal truncated alpha-synuclein enhances full-length alpha-synuclein-induced pathology.

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0027959

21 January 2018

Defining the dopamine transporter proteome by convergent biochemical and in silico analyses.

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0027959

21 January 2018

Rapid and intermittent cotransport of slow component-b proteins.

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21 January 2018

Alpha-synuclein pathology in Parkinson's and Alzheimer's disease brain: incidence and topographic distribution--a pilot study.

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21 January 2018

Alpha-synuclein lesions in normal aging, Parkinson disease, and Alzheimer disease: evidence from the Baltimore Longitudinal Study of Aging (BLSA).

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0027959

21 January 2018

Cerebral alterations in a MPTP-mouse model of Parkinson?s disease ? an immunocytochemical study

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0027959

21 January 2018

Syntaxin 1A and receptor for activated C kinase interact with the N-terminal region of human dopamine transporter

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0027959

21 January 2018

The dopamine transporter is differentially regulated after dopaminergic lesion

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0027959

21 January 2018

alpha-Synuclein pathology in the neostriatum in Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22163275

12 December 2020

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10.1371/JOURNAL.PONE.0027959

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2011PLoSO...627959B

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