(Q24309608)

English

Proline-rich tyrosine kinase 2 (Pyk2) promotes proliferation and invasiveness of hepatocellular carcinoma cells through c-Src/ERK activation

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scholarly article

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Proline-rich tyrosine kinase 2 (Pyk2) promotes proliferation and invasiveness of hepatocellular carcinoma cells through c-Src/ERK activation (English)

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protein tyrosine kinase 2 beta

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GOA release 2020-03-11

hepatocellular carcinoma

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based on heuristic

inferred from title

neoplastic invasiveness

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based on heuristic

inferred from title

author name string

Chris K Sun

1

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Kwan Man

2

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Kevin T Ng

3

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Joanna W Ho

4

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Zophia X Lim

5

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Qiao Cheng

6

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Chung-Mau Lo

7

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Ronnie T Poon

8

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Sheung-Tat Fan

9

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language of work or name

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publication date

November 2008

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29

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2096-105

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11

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Hepatocellular carcinoma pathogenesis: from genes to environment

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

21 January 2018

Review article: Overview of medical treatments in unresectable hepatocellular carcinoma--an impossible meta-analysis?

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

21 January 2018

The significance of proline-rich tyrosine kinase2 (Pyk2) on hepatocellular carcinoma progression and recurrence.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

21 January 2018

Focal adhesion kinase: in command and control of cell motility

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

21 January 2018

Mammary tumors expressing the neu proto-oncogene possess elevated c-Src tyrosine kinase activity

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

21 January 2018

Altered regulation of Src upon cell detachment protects human lung adenocarcinoma cells from anoikis

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

21 January 2018

Adhesion-linked kinases in cancer; emphasis on src, focal adhesion kinase and PI 3-kinase

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

21 January 2018

Crystal structures of c-Src reveal features of its autoinhibitory mechanism

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

21 January 2018

The MAPK signalling pathways and colorectal cancer

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

21 January 2018

MEK/ERK signaling is a critical mediator for integrin-induced cell scattering in highly metastatic hepatocellular carcinoma cells

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

21 January 2018

Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

21 January 2018

Graft injury in relation to graft size in right lobe live donor liver transplantation: a study of hepatic sinusoidal injury in correlation with portal hemodynamics and intragraft gene expression

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

21 January 2018

In vivo monitoring of tumor relapse and metastasis using bioluminescent PC-3M-luc-C6 cells in murine models of human prostate cancer

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

21 January 2018

Bioluminescent imaging (BLI) to improve and refine traditional murine models of tumor growth and metastasis

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

21 January 2018

Advancing animal models of neoplasia through in vivo bioluminescence imaging

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

21 January 2018

FTY720: a promising agent for treatment of metastatic hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

21 January 2018

Effects of a novel immunomodulating agent, FTY720, on tumor growth and angiogenesis in hepatocellular carcinoma.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

21 January 2018

FTY720 attenuates hepatic ischemia-reperfusion injury in normal and cirrhotic livers.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

21 January 2018

Paxillin: a focal adhesion-associated adaptor protein

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

21 January 2018

Focal adhesion targeting: the critical determinant of FAK regulation and substrate phosphorylation

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

21 January 2018

The focal adhesion targeting (FAT) region of focal adhesion kinase is a four-helix bundle that binds paxillin

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

21 January 2018

The role of focal-adhesion kinase in cancer - a new therapeutic opportunity

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

21 January 2018

New insights into the metastasis-associated 67 kD laminin receptor

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

21 January 2018

Laminin-5 (laminin-332): Unique biological activity and role in tumor growth and invasion

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

21 January 2018

Integrin signalling during tumour progression

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

21 January 2018

Integrin-regulated FAK-Src signaling in normal and cancer cells

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

21 January 2018

FAK integrates growth-factor and integrin signals to promote cell migration

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

21 January 2018

Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

21 January 2018

Recent progress in targeting the Raf/MEK/ERK pathway with inhibitors in cancer drug discovery

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

21 January 2018

Site-specific differences in pp60c-src activity in human colorectal metastases

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

7 January 2021

based on heuristic

inferred from DOI database lookup

Clinical trials in primary hepatocellular carcinoma: current status and future directions

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell signaling by receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

7 January 2021

based on heuristic

inferred from DOI database lookup

Hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

7 January 2021

based on heuristic

inferred from DOI database lookup

Three-dimensional structure of the tyrosine kinase c-Src

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

7 January 2021

based on heuristic

inferred from DOI database lookup

Co-regulation and Physical Association of the 67-kDa Monomeric Laminin Receptor and the α6β4 Integrin

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

7 January 2021

based on heuristic

inferred from DOI database lookup

Down-regulation by antisense oligonucleotides establishes a role for the proline-rich tyrosine kinase PYK2 in angiotensin ii-induced signaling in vascular smooth muscle

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

7 January 2021

based on heuristic

inferred from DOI database lookup

The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular regulation of cellular invasion--role of gelatinase A and TIMP-2.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

7 January 2021

based on heuristic

inferred from DOI database lookup

Proepithelin Promotes Migration and Invasion of 5637 Bladder Cancer Cells through the Activation of ERK1/2 and the Formation of a Paxillin/FAK/ERK Complex

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

7 January 2021

based on heuristic

inferred from DOI database lookup

Increase in activity and level of pp60c-src in progressive stages of human colorectal cancer

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN203

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1093/CARCIN/BGN203

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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