(Q24312074)

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Identification and characterization of proteins interacting with SIRT1 and SIRT3: implications in the anti-aging and metabolic effects of sirtuins

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Identification and characterization of proteins interacting with SIRT1 and SIRT3: implications in the anti-aging and metabolic effects of sirtuins (English)

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Paul Michel Georges Remi Vanhoutte

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Paul M Vanhoutte

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author name string

Ivy K M Law

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Ling Liu

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Aimin Xu

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Karen S L Lam

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Chi-Ming Che

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Priscilla T Y Leung

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Yu Wang

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publication date

May 2009

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2444-56

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Expression of heat shock protein 70 is altered by age and diet at the level of transcription

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Acetyl-coenzyme A carboxylases: versatile targets for drug discovery

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Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity

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Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins

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Hsp70 and aging

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Effects of Aging and Anti-Aging Caloric Restrictions on Carbonyl and Heat Shock Protein Levels and Expression

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A new role for a yeast transcriptional silencer gene, SIR2, in regulation of recombination in ribosomal DNA.

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SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells

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Increased dosage of mammalian Sir2 in pancreatic beta cells enhances glucose-stimulated insulin secretion in mice

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Conserved metabolic regulatory functions of sirtuins

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Sirtuin-mediated deacetylation pathway stabilizes Werner syndrome protein

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Silent information regulator 2 (SIRT1) attenuates oxidative stress-induced mesangial cell apoptosis via p53 deacetylation

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C. elegans 14-3-3 proteins regulate life span and interact with SIR-2.1 and DAF-16/FOXO.

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Expression and localization of Werner syndrome protein is modulated by SIRT1 and PML.

1 reference

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Substrate and functional diversity of lysine acetylation revealed by a proteomics survey

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A novel VNTR enhancer within the SIRT3 gene, a human homologue of SIR2, is associated with survival at oldest ages.

1 reference

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An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing

1 reference

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hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

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Chaperones and aging: role in neurodegeneration and in other civilizational diseases

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Characterization of a human gene with sequence homology to Saccharomyces cerevisiae SIR2

1 reference

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Variability of the SIRT3 gene, human silent information regulator Sir2 homologue, and survivorship in the elderly

1 reference

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Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation

1 reference

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Human Sir2 and the 'silencing' of p53 activity

1 reference

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Hsp70 attenuates hypoxia/reoxygenation-induced activation of poly(ADP-ribose) synthetase in the nucleus of adult rat cardiomyocytes

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Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.200800738

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based on heuristic

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Surfing the p53 network

1 reference

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based on heuristic

inferred from DOI database lookup

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

1 reference

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Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma

1 reference

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Sirtuin activators mimic caloric restriction and delay ageing in metazoans

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.200800738

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Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

1 reference

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Sirtuins as potential targets for metabolic syndrome

1 reference

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Sirtuins: critical regulators at the crossroads between cancer and aging

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Sirtuins in mammals: insights into their biological function

1 reference

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based on heuristic

inferred from DOI database lookup

The human SIRT3 protein deacetylase is exclusively mitochondrial

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Sir2 mediates longevity in the fly through a pathway related to calorie restriction

1 reference

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based on heuristic

inferred from DOI database lookup

Distinct pathways of insulin-regulated versus diabetes-regulated gene expression: an in vivo analysis in MIRKO mice

1 reference

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based on heuristic

inferred from DOI database lookup

Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.200800738

7 January 2021

based on heuristic

inferred from DOI database lookup

Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Fasting-dependent glucose and lipid metabolic response through hepatic sirtuin 1

1 reference

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A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

1 reference

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based on heuristic

inferred from DOI database lookup

The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.200800738

7 January 2021

based on heuristic

inferred from DOI database lookup

SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.200800738

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based on heuristic

inferred from DOI database lookup

Silent information regulator 2 family of NAD- dependent histone/protein deacetylases generates a unique product, 1-O-acetyl-ADP-ribose

1 reference

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based on heuristic

inferred from DOI database lookup

A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family.

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.200800738

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based on heuristic

inferred from DOI database lookup

DNA damage-induced translocation of the Werner helicase is regulated by acetylation

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.200800738

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of WRN protein cellular localization and enzymatic activities by SIRT1-mediated deacetylation

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.200800738

7 January 2021

based on heuristic

inferred from DOI database lookup

SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.200800738

7 January 2021

based on heuristic

inferred from DOI database lookup

Sirtuins: the 'magnificent seven', function, metabolism and longevity

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.200800738

7 January 2021

based on heuristic

inferred from DOI database lookup

The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.200800738

7 January 2021

based on heuristic

inferred from DOI database lookup

Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.200800738

7 January 2021

based on heuristic

inferred from DOI database lookup

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.200800738

7 January 2021

based on heuristic

inferred from DOI database lookup

SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.200800738

7 January 2021

based on heuristic

inferred from DOI database lookup

Mammalian sirtuins--emerging roles in physiology, aging, and calorie restriction

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.200800738

7 January 2021

based on heuristic

inferred from DOI database lookup

The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.200800738

7 January 2021

based on heuristic

inferred from DOI database lookup

SIRT1 transgenic mice show phenotypes resembling calorie restriction

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.200800738

7 January 2021

based on heuristic

inferred from DOI database lookup

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.200800738

7 January 2021

based on heuristic

inferred from DOI database lookup

Increase in activity during calorie restriction requires Sirt1

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.200800738

7 January 2021

based on heuristic

inferred from DOI database lookup

WRN controls formation of extrachromosomal telomeric circles and is required for TRF2DeltaB-mediated telomere shortening

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.200800738

7 January 2021

based on heuristic

inferred from DOI database lookup

Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.200800738

7 January 2021

based on heuristic

inferred from DOI database lookup

Sirt1 regulates aging and resistance to oxidative stress in the heart

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.200800738

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of Hsp70 in age-related diseases and the prevention of cancer

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.200800738

7 January 2021

based on heuristic

inferred from DOI database lookup

Proteome alterations in rat mitochondria caused by aging

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.200800738

7 January 2021

based on heuristic

inferred from DOI database lookup

Sirtuin functions in health and disease

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.200800738

7 January 2021

based on heuristic

inferred from DOI database lookup

Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.200800738

7 January 2021

based on heuristic

inferred from DOI database lookup

SirT1 regulates energy metabolism and response to caloric restriction in mice

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.200800738

7 January 2021

based on heuristic

inferred from DOI database lookup

The nuclear matrix is a thermolabile cellular structure

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.200800738

7 January 2021

based on heuristic

inferred from DOI database lookup

Adiponectin-induced endothelial nitric oxide synthase activation and nitric oxide production are mediated by APPL1 in endothelial cells.

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.200800738

7 January 2021

based on heuristic

inferred from DOI database lookup

Werner syndrome: molecular insights into the relationships between defective DNA metabolism, genomic instability, cancer and aging

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.200800738

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/PMIC.200800738

1 reference

Consolidated OpenCitations Corpus – April 2017

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OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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