(Q24313179)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18356043%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

title

Identification of the human cytochrome P450 enzymes involved in the in vitro biotransformation of lynestrenol and norethindrone (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18356043%20AND%20SRC:MED&resulttype=core&format=json

cytochrome P450 family 3 subfamily A member 4

4 January 2020

main subject

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cytochrome P450 family 2 subfamily A member 6

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cytochrome P450 family 2 subfamily E member 1

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cytochrome P450 family 1 subfamily A member 2

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cytochrome P450 family 2 subfamily C member 9

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cytochrome P450 family 2 subfamily D member 6

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cytochrome P450 family 2 subfamily B member 6

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cytochrome P450 family 2 subfamily C member 19

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steroid hydroxylase activity

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author

Miia Turpeinen

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18356043%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

5

Olavi Pelkonen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18356043%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

author name string

Tuomas Korhonen

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18356043%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Ari Tolonen

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18356043%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

Kari Laine

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18356043%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

language of work or name

English

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publication date

15 February 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18356043%20AND%20SRC:MED&resulttype=core&format=json

The Journal of Steroid Biochemistry and Molecular Biology

4 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18356043%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

volume

110

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18356043%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

page(s)

56-66

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18356043%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

issue

1-2

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Kinetics of norethindrone in women; I. Radioimmunoassay and concentrations during multiple dosing

4 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

Kinetics of norethindrone in women. II. Single-dose kinetics

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

Determination of estrogens and progestogens by mass spectrometric techniques (GC/MS, LC/MS and LC/MS/MS)

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

Screening for anabolic steroids and related compounds in illegal cocktails by liquid chromatography/time-of-flight mass spectrometry and liquid chromatography/quadrupole time-of-flight tandem mass spectrometry with accurate mass measurement

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

Validation of methods for CYP2C9 genotyping: frequencies of mutant alleles in a Swedish population.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

Hydroxylation polymorphisms of debrisoquine and mephenytoin in European populations

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

The effect of rifampicin on norethisterone pharmacokinetics

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

Pharmacokinetics of norethindrone acetate in women

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

Intraindividual comparison of pharmacokinetic parameters of d-norgestrel, lynestrenol and cyproterone acetate in 6 women

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

Serum levels and pharmacokinetics of norethisterone after ingestion of lynestrenol: its relation to dose and stage of the menstrual cycle

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

Pharmacokinetics, pharmacodynamic and endometrial effects of a single dose of 200 mg norethisterone enanthate

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

Metabolism of levonorgestrel, norethindrone, and structurally related contraceptive steroids

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

The interaction between St John's wort and an oral contraceptive

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

Multiple P450 substrates in a single run: rapid and comprehensive in vitro interaction assay

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

Cytochrome P450 (CYP) inhibition screening: comparison of three tests.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

Classification and pharmacology of progestins

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

Cytochrome P-450-linked monooxygenase system and drug-induced spectral interactions in human liver microsomes

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

The effects of rifampin and rifabutin on the pharmacokinetics and pharmacodynamics of a combination oral contraceptive

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

Substrate SARs in human P450s

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

Gastrointestinal and systemic uptake of bismuth in mice after oral exposure

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

Interethnic differences in genetic polymorphism of debrisoquin and mephenytoin hydroxylation between Japanese and Caucasian populations

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

Validation of the tolbutamide metabolic ratio for population screening with use of sulfaphenazole to produce model phenotypic poor metabolizers

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylations of debrisoquin and S-mephenytoin

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

Simulation and prediction of in vivo drug metabolism in human populations from in vitro data

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

Effect of topiramate or carbamazepine on the pharmacokinetics of an oral contraceptive containing norethindrone and ethinyl estradiol in healthy obese and nonobese female subjects

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

Inhibition and induction of human cytochrome P450 (CYP) enzymes

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

In vitro inhibition studies of tolbutamide hydroxylase activity of human liver microsomes by azoles, sulphonamides and quinolines

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

Prediction of drug metabolism and interactions on the basis of in vitro investigations.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

Selective inhibition of CYP2B6-catalyzed bupropion hydroxylation in human liver microsomes in vitro

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

Human extrahepatic cytochromes P450: function in xenobiotic metabolism and tissue-selective chemical toxicity in the respiratory and gastrointestinal tracts

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

Effect of antifungal drugs on cytochrome P450 (CYP) 1A2, CYP2D6, and CYP2E1 activities in human liver microsomes

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

Metabolism of [4-14C]lynestrenol in man

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

Metabolism of lynestrenol to norethisterone by liver homogenate

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

Effects of the antifungal agents on oxidative drug metabolism: clinical relevance

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

Pharmacokinetic interaction between bosentan and the oral contraceptives norethisterone and ethinyl estradiol.

1 reference

https://api.crossref.org/works/10.1016%2FJ.JSBMB.2007.09.025

7 January 2021

10.1016/J.JSBMB.2007.09.025

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18356043%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1 reference