(Q24313575)

Gene Ontology release 2020-05-02

1 reference

Gene Ontology release 2020-05-02

1 reference

Gene Ontology release 2020-05-02

1 reference

GOA release 2020-03-11

Proprotein convertase subtilisin/kexin type 9

1 reference

Journal of Biological Chemistry

GOA release 2020-03-11

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Nabil G Seidah

3

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author name string

Gaétan Mayer

series ordinal

1

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Steve Poirier

series ordinal

2

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language of work or name

English

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publication date

14 November 2008

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published in

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volume

283

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issue

46

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page(s)

31791-801

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cites work

The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

The activation and physiological functions of the proprotein convertases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

NARC-1/PCSK9 and its natural mutants: zymogen cleavage and effects on the low density lipoprotein (LDL) receptor and LDL cholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

Adenoviral-mediated expression of Pcsk9 in mice results in a low-density lipoprotein receptor knockout phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

Sequence variations in PCSK9, low LDL, and protection against coronary heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

Translating molecular discoveries into new therapies for atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

Mutations in PCSK9 cause autosomal dominant hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

Mapping the genetic architecture of gene expression in human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

The proprotein convertases are potential targets in the treatment of dyslipidemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

Proprotein convertase subtilisin/kexin type 9 (PCSK9): hepatocyte-specific low-density lipoprotein receptor degradation and critical role in mouse liver regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

The cellular trafficking of the secretory proprotein convertase PCSK9 and its dependence on the LDLR

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

Effect of mutations in the PCSK9 gene on the cell surface LDL receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

Post-transcriptional regulation of low density lipoprotein receptor protein by proprotein convertase subtilisin/kexin type 9a in mouse liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

Overexpression of PCSK9 accelerates the degradation of the LDLR in a post-endoplasmic reticulum compartment

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

Catalytic activity is not required for secreted PCSK9 to reduce low density lipoprotein receptors in HepG2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

The proprotein convertase PCSK9 induces the degradation of low density lipoprotein receptor (LDLR) and its closest family members VLDLR and ApoER2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

Binding of proprotein convertase subtilisin/kexin type 9 to epidermal growth factor-like repeat A of low density lipoprotein receptor decreases receptor recycling and increases degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

Molecular basis for LDL receptor recognition by PCSK9

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

The self-inhibited structure of full-length PCSK9 at 1.9 A reveals structural homology with resistin within the C-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

A spectrum of PCSK9 alleles contributes to plasma levels of low-density lipoprotein cholesterol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

The proprotein convertase (PC) PCSK9 is inactivated by furin and/or PC5/6A: functional consequences of natural mutations and post-translational modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

Structure-function analysis of the prosegment of the proprotein convertase PC5A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

The regulated cell surface zymogen activation of the proprotein convertase PC5A directs the processing of its secretory substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

The p11 subunit of the annexin II tetramer plays a key role in the stimulation of t-PA-dependent plasminogen activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

Extracellular annexin II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

Cell surface complex of cathepsin B/annexin II tetramer in malignant progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

Molecular biology of PCSK9: its role in LDL metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

The N-terminal domain of annexin 2 serves as a secondary binding site during membrane bridging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

The Low-Density Lipoprotein Pathway and its Relation to Atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

Biomedicine. Lowering LDL--not only how low, but how long?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

PCSK9 function and physiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

Functional characterization of Narc 1, a novel proteinase related to proteinase K

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

Annexins--unique membrane binding proteins with diverse functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

Caveolae: uniform structures with multiple functions in signaling, cell growth, and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

An annexin 2 phosphorylation switch mediates p11-dependent translocation of annexin 2 to the cell surface

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

Cell surface annexin II is a high affinity receptor for the alternatively spliced segment of tenascin-C

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

Annexin II regulates fibrin homeostasis and neoangiogenesis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

Plasma PCSK9 preferentially reduces liver LDL receptors in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

Gene expression patterns in isolated keloid fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

Expression of annexins on the surfaces of non-metastatic and metastatic human and rodent tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

inferred from DOI database lookup

7 January 2021

based on heuristic

Translocation of cytosolic annexin 2 to a Triton-insoluble membrane subdomain upon nicotine stimulation of chromaffin cultured cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M805971200

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1074/JBC.M805971200

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

18799458

1 reference

Consolidated OpenCitations Corpus – April 2017