(Q24321723)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1902110

regulation of mitochondrial membrane permeability involved in apoptotic process

2 references

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1902108

negative regulation of mitochondrial membrane permeability involved in apoptotic process

GOA release 2020-03-11

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1902109

Thioesterase superfamily member 4

1 reference

GOA release 2020-03-11

1 reference

7

Brian A Hemmings

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author name string

Arnaud Parcellier

1

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Lionel A Tintignac

2

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Elena Zhuravleva

3

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Peter Cron

4

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Susanne Schenk

5

0 references

Lana Bozulic

Mechanism of activation of protein kinase B by insulin and IGF-1

6

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language of work or name

English

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publication date

April 2009

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published in

Cellular Signalling

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volume

21

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page(s)

639-50

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issue

4

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cites work

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Caspase-dependent chemotherapy-induced death of glioma cells requires mitochondrial cytochrome c release

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Predicting subcellular localization of proteins based on their N-terminal amino acid sequence

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The Akt-mTOR tango and its relevance to cancer

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Mitochondria, oxidants, and aging

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Apoptotic pathways: ten minutes to dead

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Connecting mitochondria and innate immunity

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Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling

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7 January 2021

OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion

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7 January 2021

OPA1 and PARL keep a lid on apoptosis

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7 January 2021

AKT/PKB signaling: navigating downstream

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A mitochondrial protein compendium elucidates complex I disease biology

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PKB and the mitochondria: AKTing on apoptosis

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Mitochondrial medicine: a metabolic perspective on the pathology of oxidative phosphorylation disorders

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Mitochondria: more than just a powerhouse

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AKT-1 regulates DNA-damage-induced germline apoptosis in C. elegans

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7 January 2021

Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability

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7 January 2021

Centrosome-associated NDR kinase regulates centrosome duplication

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7 January 2021

PKBalpha/Akt1 acts downstream of DNA-PK in the DNA double-strand break response and promotes survival

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7 January 2021

Chopped, trapped or tacked--protein translocation into the IMS of mitochondria

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7 January 2021

LETM1, a gene deleted in Wolf-Hirschhorn syndrome, encodes an evolutionarily conserved mitochondrial protein

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7 January 2021

Alterations in the expression of cytochrome c oxidase subunits in doxorubicin-resistant leukemia K562 cells.

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7 January 2021

PI3K: downstream AKTion blocks apoptosis

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7 January 2021

Mitochondrial processing peptidases

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7 January 2021

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

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7 January 2021

PSORT: a program for detecting sorting signals in proteins and predicting their subcellular localization

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7 January 2021

Crystal structures of mitochondrial processing peptidase reveal the mode for specific cleavage of import signal sequences

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7 January 2021

The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis

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7 January 2021

Human mammary epithelial cell transformation through the activation of phosphatidylinositol 3-kinase

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7 January 2021

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

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7 January 2021

Injected cytochrome c induces apoptosis

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7 January 2021

Colorectal cancer: mutations in a signalling pathway

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7 January 2021

Viral pro-survival proteins block separate stages in Bax activation but changes in mitochondrial ultrastructure still occur

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7 January 2021

DRP-1-mediated mitochondrial fragmentation during EGL-1-induced cell death in C. elegans

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7 January 2021

Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein

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7 January 2021

The BCL-2 protein family: opposing activities that mediate cell death

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7 January 2021

The protein import motor of mitochondria

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7 January 2021

A cut short to death: Parl and Opa1 in the regulation of mitochondrial morphology and apoptosis

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7 January 2021

Cell death modalities: classification and pathophysiological implications

1 reference

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7 January 2021

DNA-PKcs, but not TLR9, is required for activation of Akt by CpG-DNA.

1 reference

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7 January 2021

Export of mitochondrial AIF in response to proapoptotic stimuli depends on processing at the intermembrane space

1 reference

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7 January 2021

Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector

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7 January 2021

Lentivirus-mediated carboxyl-terminal modulator protein gene transfection via aerosol in lungs of K-ras null mice.

1 reference

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7 January 2021

The protein kinase PKB/Akt regulates cell survival and apoptosis by inhibiting Bax conformational change

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7 January 2021

AKT and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor cell growth

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https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

The many shapes of mitochondrial death

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7 January 2021

Mitochondrial mutations in cancer

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7 January 2021

Gaining access to the cytosol: the technique and some applications of electropermeabilization

1 reference

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7 January 2021

Physiological roles of PKB/Akt isoforms in development and disease

1 reference

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7 January 2021

Rapid accumulation of Akt in mitochondria following phosphatidylinositol 3-kinase activation

1 reference

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7 January 2021

p53 stabilization in response to DNA damage requires Akt/PKB and DNA-PK.

1 reference

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7 January 2021

EPAC and PKA allow cAMP dual control over DNA-PK nuclear translocation.

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7 January 2021

Role of translocation in the activation and function of protein kinase B

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7 January 2021

Evidence That 3-Phosphoinositide-dependent Protein Kinase-1 Mediates Phosphorylation of p70 S6 Kinasein Vivoat Thr-412 as well as Thr-252

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

Regulation of protein kinase B/Akt-serine 473 phosphorylation by integrin-linked kinase: critical roles for kinase activity and amino acids arginine 211 and serine 343

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

Fluorescent indicators for Akt/protein kinase B and dynamics of Akt activity visualized in living cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

Phosphorylation of Bax Ser184 by Akt regulates its activity and apoptosis in neutrophils

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

Identification of a PKB/Akt hydrophobic motif Ser-473 kinase as DNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

Protein kinase C betaII regulates Akt phosphorylation on Ser-473 in a cell type- and stimulus-specific fashion.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

Full activation of PKB/Akt in response to insulin or ionizing radiation is mediated through ATM.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

Spatio-temporal dynamics of protein kinase B/Akt signaling revealed by a genetically encoded fluorescent reporter

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

Quantitative analysis of anti-apoptotic function of Akt in Akt1 and Akt2 double knock-out mouse embryonic fibroblast cells under normal and stressed conditions

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

RETRACTED: Akt attenuation of the serine protease activity of HtrA2/Omi through phosphorylation of serine 212

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

In vivo analysis of protein kinase B (PKB)/Akt regulation in DNA-PKcs-null mice reveals a role for PKB/Akt in DNA damage response and tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

Conformation of the Bax C-terminus regulates subcellular location and cell death

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

LETM1, deleted in Wolf-Hirschhorn syndrome is required for normal mitochondrial morphology and cellular viability

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

Hypermethylation and transcriptional downregulation of the carboxyl-terminal modulator protein gene in glioblastomas

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

Cellular survival: a play in three Akts

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

Carboxyl-terminal modulator protein (CTMP), a negative regulator of PKB/Akt and v-Akt at the plasma membrane

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

The pathophysiology of mitochondrial cell death

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

Akt signaling: linking membrane events to life and death decisions

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

Mitochondria and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

Roles of the Ras-MEK-mitogen-activated protein kinase and phosphatidylinositol 3-kinase-Akt-mTOR pathways in Jaagsiekte sheep retrovirus-induced transformation of rodent fibroblast and epithelial cell lines

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

Activation of Akt (protein kinase B) in mammary epithelium provides a critical cell survival signal required for tumor progression

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

Akt inhibits apoptosis downstream of BID cleavage via a glucose-dependent mechanism involving mitochondrial hexokinases

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

Mutant MyoD lacking Cdc2 phosphorylation sites delays M-phase entry

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

Carboxy-terminal modulator protein induces Akt phosphorylation and activation, thereby enhancing antiapoptotic, glycogen synthetic, and glucose uptake pathways

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

Cardiac protection by mitoKATP channels is dependent on Akt translocation from cytosol to mitochondria during late preconditioning

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

Akt activation is necessary for growth factor-induced trafficking of functional K(Ca) channels in developing parasympathetic neurons

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

Mitochondrial membrane permeabilization in cell death

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

Bcl-2-family proteins and hematologic malignancies: history and future prospects

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

Protein kinase B/Akt at a glance

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

The mitochondrial targeting sequence tilts the balance between mitochondrial and cytosolic dual localization.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

Metabolic catastrophe as a means to cancer cell death

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

Intramolecular and intermolecular interactions of protein kinase B define its activation in vivo

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELLSIG.2009.01.016

7 January 2021

10.1016/J.CELLSIG.2009.01.016

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

576283

576283

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference