(Q26749321)

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31 March 2020

2 references

13 November 2020

19 July 2021

The ubiquitin proteasomal system: a potential target for the management of Alzheimer's disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27028664%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

0 references

7 references

25 April 2019

25 June 2019

28 September 2019

16 November 2019

22 December 2019

13 November 2020

1 reference

28 September 2019

macromolecular substance

1 reference

16 November 2019

1 reference

22 December 2019

1 reference

13 November 2020

proteasome endopeptidase complex

1 reference

19 July 2021

1

1 reference

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31 March 2020

Sahabuddin Ahmed

8

1 reference

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31 March 2020

author name string

Nityanand Bolshette

2

1 reference

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31 March 2020

Ashutosh Ahire

3

1 reference

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31 March 2020

Rohit Pardeshi

4

1 reference

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31 March 2020

Krishan Thakur

5

1 reference

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31 March 2020

Cristiana Trandafir

6

1 reference

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31 March 2020

Alexandru Istrate

7

1 reference

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31 March 2020

Mangala Lahkar

9

1 reference

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31 March 2020

Dafin F Muresanu

10

1 reference

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31 March 2020

Maria Balea

11

1 reference

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31 March 2020

language of work or name

English

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publication date

29 March 2016

1 reference

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Journal of Cellular and Molecular Medicine

31 March 2020

1 July 2016

2 references

13 November 2020

19 July 2021

8 references

25 April 2019

25 June 2019

28 September 2019

16 November 2019

22 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27028664%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

13 November 2020

19 July 2021

20

1 reference

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31 March 2020

issue

7

1 reference

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31 March 2020

page(s)

1392-1407

1 reference

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Creative Commons Attribution

31 March 2020

copyright license

7 references

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on focus list of Wikimedia project

ScienceSource

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Protein aggregation and neurodegenerative disease

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An arsenite-inducible 19S regulatory particle-associated protein adapts proteasomes to proteotoxicity

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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The ubiquitin-proteasome system in neurodegenerative diseases: precipitating factor, yet part of the solution

28 September 2017

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Targeting Hsp90 and its co-chaperones to treat Alzheimer's disease

28 September 2017

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Acetylation: a new key to unlock tau's role in neurodegeneration

28 September 2017

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Alzheimer's disease: is a vaccine possible?

28 September 2017

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Relationship between amyloid-beta and the ubiquitin-proteasome system in Alzheimer's disease

28 September 2017

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New treatment strategies for Alzheimer's disease: is there a hope?

28 September 2017

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Peptides that activate the 20S proteasome by gate opening increased oxidized protein removal and reduced protein aggregation

28 September 2017

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Current and emerging therapies for Alzheimer's disease

28 September 2017

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The proteasome and the degradation of oxidized proteins: Part I-structure of proteasomes.

28 September 2017

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Brain site-specific proteome changes in aging-related dementia

28 September 2017

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Rapamycin, Autophagy, and Alzheimer's Disease

28 September 2017

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Treatment with bexarotene, a compound that increases apolipoprotein-E, provides no cognitive benefit in mutant APP/PS1 mice

28 September 2017

1 reference

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Targeting ubiquilin-1 in Alzheimer's disease

28 September 2017

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The ART-Rsp5 ubiquitin ligase network comprises a plasma membrane quality control system that protects yeast cells from proteotoxic stress

28 September 2017

1 reference

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The ubiquitin proteasome system as a potential target for the treatment of neurodegenerative diseases

28 September 2017

1 reference

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Crosstalk between the ubiquitin-proteasome system and autophagy in a human cellular model of Alzheimer's disease

28 September 2017

1 reference

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The synaptic accumulation of hyperphosphorylated tau oligomers in Alzheimer disease is associated with dysfunction of the ubiquitin-proteasome system

28 September 2017

1 reference

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Beyond amyloid: the future of therapeutics for Alzheimer's disease

28 September 2017

1 reference

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Degradation of tau protein by autophagy and proteasomal pathways

28 September 2017

1 reference

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Protein homeostasis, aging and Alzheimer's disease

28 September 2017

1 reference

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Stable incorporation of ATPase subunits into 19 S regulatory particle of human proteasome requires nucleotide binding and C-terminal tails

28 September 2017

1 reference

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Control of BACE1 degradation and APP processing by ubiquitin carboxyl-terminal hydrolase L1.

28 September 2017

1 reference

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Aβ-degrading enzymes: potential for treatment of Alzheimer disease.

28 September 2017

1 reference

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Proteasomal AAA-ATPases: structure and function.

28 September 2017

1 reference

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Disease-modifying treatments for Alzheimer's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Stem cell therapy for Alzheimer's disease

28 September 2017

1 reference

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The Hsp90 kinase co-chaperone Cdc37 regulates tau stability and phosphorylation dynamics.

28 September 2017

1 reference

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28 September 2017

Proteasome activators

1 reference

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Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits

28 September 2017

1 reference

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Hsp90 regulates tau pathology through co-chaperone complexes in Alzheimer's disease

28 September 2017

1 reference

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Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden

28 September 2017

1 reference

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Structure, assembly and homeostatic regulation of the 26S proteasome

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Role of ubiquitin-proteasome-mediated proteolysis in nervous system disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Controlling amyloid-beta peptide(1-42) oligomerization and toxicity by fluorinated nanoparticles

28 September 2017

1 reference

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Alzheimer's disease: clinical trials and drug development

28 September 2017

1 reference

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The ubiquitin-proteasome pathway and synaptic plasticity

28 September 2017

1 reference

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Hsp70 ATPase Modulators as Therapeutics for Alzheimer's and other Neurodegenerative Diseases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Assembly, structure, and function of the 26S proteasome.

28 September 2017

1 reference

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Glutamate receptors, neurotoxicity and neurodegeneration

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Ubiquitin/proteasome pathway impairment in neurodegeneration: therapeutic implications

28 September 2017

1 reference

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Therapeutic strategies within the ubiquitin proteasome system.

28 September 2017

1 reference

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Neurofibrillary and neurodegenerative pathology in APP-transgenic mice injected with AAV2-mutant TAU: neuroprotective effects of Cerebrolysin

28 September 2017

1 reference

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The proteasome: overview of structure and functions

28 September 2017

1 reference

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Ubiquitin, the proteasome and protein degradation in neuronal function and dysfunction

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Targeted intracellular protein degradation induced by a small molecule: En route to chemical proteomics

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Autophagy: a lysosomal degradation pathway with a central role in health and disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Quality control of the proteins associated with neurodegenerative diseases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Role of the ubiquitin proteasome system in Alzheimer's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Autophagy, amyloidogenesis and Alzheimer disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

BAG-1 associates with Hsc70.Tau complex and regulates the proteasomal degradation of Tau protein.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Heat shock proteins and amateur chaperones in amyloid-Beta accumulation and clearance in Alzheimer's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Activation and inhibition of the proteasome by betulinic acid and its derivatives

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Novel therapeutic strategies for the treatment of protein-misfolding diseases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Abeta inhibits the proteasome and enhances amyloid and tau accumulation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Roles of heat-shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Intermediates: ubiquitous species on folding energy landscapes?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

ATP binding and ATP hydrolysis play distinct roles in the function of 26S proteasome

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Potential compensatory responses through autophagic/lysosomal pathways in neurodegenerative diseases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Drug discovery in the ubiquitin-proteasome system.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Deletion of the ubiquitin ligase CHIP leads to the accumulation, but not the aggregation, of both endogenous phospho- and caspase-3-cleaved tau species.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Ubiquitin-proteasome pathway components as therapeutic targets for CNS maladies

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

The amyloid stretch hypothesis: recruiting proteins toward the dark side

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

The proteasome in Alzheimer's disease and Parkinson's disease: lessons from ubiquitin B+1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Amyloid peptide attenuates the proteasome activity in neuronal cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

In vivo evidence of CHIP up-regulation attenuating tau aggregation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Intracellular protein degradation: from a vague idea thru the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Degradation of BACE by the ubiquitin-proteasome pathway

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Role of tau protein in both physiological and pathological conditions.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Intracellular localization of proteasomes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Impairment of proteasome structure and function in aging.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Role and function of the 26S proteasome in proliferation and apoptosis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

The substrate translocation channel of the proteasome

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Degradation of oxidized proteins by the 20S proteasome.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Chaperone-dependent Neurodegeneration: A Molecular Perspective on Therapeutic Intervention

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Polyubiquitin chain assembly and organization determine the dynamics of protein activation and degradation

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Increased vesicular glutamate transporter expression causes excitotoxic neurodegeneration.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Structure of the human 26S proteasome: subunit radial displacements open the gate into the proteolytic core

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

The benzoquinone ansamycin 17-allylamino-17-demethoxygeldanamycin binds to HSP90 and shares important biologic activities with geldanamycin

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Immunoproteasome and LMP2 polymorphism in aged and Alzheimer's disease brains

31 May 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCMM.12817

Reactive glia show increased immunoproteasome activity in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCMM.12817

ATP hydrolysis by the proteasome regulatory complex PAN serves multiple functions in protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCMM.12817

Binding of human proteins to amyloid-β protofibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCMM.12817

Does metabolic failure at the synapse cause Alzheimer's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCMM.12817

Cerebrolysin decreases amyloid-beta production by regulating amyloid protein precursor maturation in a transgenic model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCMM.12817

Ubistatins inhibit proteasome-dependent degradation by binding the ubiquitin chain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCMM.12817

Heat shock protein 90 in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCMM.12817

BAG-1M is up-regulated in hippocampus of Alzheimer's disease patients and associates with tau and APP proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCMM.12817

Relationship between beta-amyloid degradation and the 26S proteasome in neural cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCMM.12817

Essential role of E2-25K/Hip-2 in mediating amyloid-beta neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCMM.12817

Mutant ubiquitin expressed in Alzheimer's disease causes neuronal death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCMM.12817

Amyloid-beta (Aβ₁₋₄₂)-induced paralysis in Caenorhabditis elegans is inhibited by the polyphenol quercetin through activation of protein degradation pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCMM.12817

Genetics of Alzheimer’s Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJCMM.12817

Therapeutic effect of exogenous hsp70 in mouse models of Alzheimer's disease

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

[Possibilities of preventive treatment of Alzheimer's disease: results of the 3-year open prospective comparative study on efficacy and safety of the course therapy with cerebrolysin and cavinton in elderly patients with the syndrome of mild cogniti

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4929298

Impaired proteasome function in Alzheimer's disease

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27028664

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Binding of amyloid beta protein to the 20 S proteasome

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27028664

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The neuronal endosomal-lysosomal system in Alzheimer's disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27028664

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/JCMM.12817

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27028664%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27028664%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

PubMed publication ID

27028664

2 references